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Glycated Hemoglobin as a Marker of Dyslipidemia in Type II Diabetic Patients


Affiliations
1 Department of Physiology, Punjab Institute of Medical Sciences Jalandhar City, Punjab, India
2 Department of Biochemistry, Punjab Institute of Medical Sciences Jalandhar City, Punjab, India
 

Background:Diabetes is an important public health problem and leading cause of cardiovascular problems its early detection and good glycemic control can reduce the complications associated with the disease.

Objective: This was a prospective study planned to evaluate the relationship of glycated haemoglobin (HbA1c) and lipid profile in type II diabetic Punjabi male population.

Material and Methods: A total of 200 diabetes type II patient ranging from age group of 30 to 70 years were included in the study after taking a preinformed written consent. The glycated haemoglobin (HbA1c)&lipid profile were performed on fully automated analyzers. The statistical analysis was done by using SPSS statistics and correlation among HbA1c and lipid profile of type II Diabetic patients was established.

Results: The mean HbA1c was in the range of 7.54 ± 1.24%. There were 61% subjects with high total cholesterol (TC) levels and 96% were with raised LDL levels. The 68% of the subjects were having lower HDL level. HbA1c demonstrated significant positive relationship with total cholesterol, TC (r=0.995), triglyceride, TG (r=0.997), high density lipoprotein cholesterol, HDL-C (r=-0.940) and with low density lipoprotein cholesterol, LDL-C (r=0.993).

Conclusion: The study concluded that HbA1c apart from acting as important diagnostic marker for glycemic control can also be used as a positive predictor of dyslipidemia in type 2 diabetics.


Keywords

HbA1c, Diabetes Mellitus, Glycemic Control, Lipid Profile, Dyslipidemia.
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  • Glycated Hemoglobin as a Marker of Dyslipidemia in Type II Diabetic Patients

Abstract Views: 235  |  PDF Views: 148

Authors

R. Arora
Department of Physiology, Punjab Institute of Medical Sciences Jalandhar City, Punjab, India
B. Thakurdas
Department of Biochemistry, Punjab Institute of Medical Sciences Jalandhar City, Punjab, India

Abstract


Background:Diabetes is an important public health problem and leading cause of cardiovascular problems its early detection and good glycemic control can reduce the complications associated with the disease.

Objective: This was a prospective study planned to evaluate the relationship of glycated haemoglobin (HbA1c) and lipid profile in type II diabetic Punjabi male population.

Material and Methods: A total of 200 diabetes type II patient ranging from age group of 30 to 70 years were included in the study after taking a preinformed written consent. The glycated haemoglobin (HbA1c)&lipid profile were performed on fully automated analyzers. The statistical analysis was done by using SPSS statistics and correlation among HbA1c and lipid profile of type II Diabetic patients was established.

Results: The mean HbA1c was in the range of 7.54 ± 1.24%. There were 61% subjects with high total cholesterol (TC) levels and 96% were with raised LDL levels. The 68% of the subjects were having lower HDL level. HbA1c demonstrated significant positive relationship with total cholesterol, TC (r=0.995), triglyceride, TG (r=0.997), high density lipoprotein cholesterol, HDL-C (r=-0.940) and with low density lipoprotein cholesterol, LDL-C (r=0.993).

Conclusion: The study concluded that HbA1c apart from acting as important diagnostic marker for glycemic control can also be used as a positive predictor of dyslipidemia in type 2 diabetics.


Keywords


HbA1c, Diabetes Mellitus, Glycemic Control, Lipid Profile, Dyslipidemia.

References





DOI: https://doi.org/10.18311/ijmds%2F2016%2F100600