International Journal of Medical and Dental Sciences

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Evaluation of Therapeutic Effect of Aloe Vera Juice and Gel in the Management of Symptomatic Oral Lichen Planus


Affiliations
1 Department of Oral Medicine and Radiology Oxford Dental College, Bangalore, India
 

Background:Oral lichen planus is a chronic inflammatory mucocutaneous disease. The anti-inflammatory, immunomodulatory and wound healing properties of aloe vera suggest its possible use in the management of oral lichen planus.

Objectives: To clinically determine the effect of aloe vera juice and gel in the management of symptomatic oral lichen planus.

Study Design: 30 subjects with symptomatic oral lichen planus and were randomly assigned into group A (n=15) and group B (n=15). Group A patients were instructed to drink 30ml of aloe vera juice twice daily before food and to apply aloe vera gel over the lesion twice daily for 8 weeks. Group B patients were instructed to apply aloe vera gel over the lesion twice daily for 8 weeks. The parameter assessed was burning sensation/pain and the size of the lesion. The follow up was done at intervals of 1 week, 2 weeks, 4 weeks and 8 weeks.

Results: The mean VAS scores of both the groups showed a statistically significant reduction (P<0.001). The reduction in the mean VAS scores of group A was more when compared with that of group B. No difference was observed with respect to the size of the lesion.

Conclusion: The study concluded that aloe vera is effective in the management of symptomatic oral lichen planus with minimal side effects.


Keywords

Aloe Vera, Lichen Planus, Erosive, Topical, Systemic.
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  • Evaluation of Therapeutic Effect of Aloe Vera Juice and Gel in the Management of Symptomatic Oral Lichen Planus

Abstract Views: 262  |  PDF Views: 169

Authors

J. S. Pol
Department of Oral Medicine and Radiology Oxford Dental College, Bangalore, India
B. A. Patil
Department of Oral Medicine and Radiology Oxford Dental College, Bangalore, India
A. Sodhi
Department of Oral Medicine and Radiology Oxford Dental College, Bangalore, India
J. Tadiparthi
Department of Oral Medicine and Radiology Oxford Dental College, Bangalore, India

Abstract


Background:Oral lichen planus is a chronic inflammatory mucocutaneous disease. The anti-inflammatory, immunomodulatory and wound healing properties of aloe vera suggest its possible use in the management of oral lichen planus.

Objectives: To clinically determine the effect of aloe vera juice and gel in the management of symptomatic oral lichen planus.

Study Design: 30 subjects with symptomatic oral lichen planus and were randomly assigned into group A (n=15) and group B (n=15). Group A patients were instructed to drink 30ml of aloe vera juice twice daily before food and to apply aloe vera gel over the lesion twice daily for 8 weeks. Group B patients were instructed to apply aloe vera gel over the lesion twice daily for 8 weeks. The parameter assessed was burning sensation/pain and the size of the lesion. The follow up was done at intervals of 1 week, 2 weeks, 4 weeks and 8 weeks.

Results: The mean VAS scores of both the groups showed a statistically significant reduction (P<0.001). The reduction in the mean VAS scores of group A was more when compared with that of group B. No difference was observed with respect to the size of the lesion.

Conclusion: The study concluded that aloe vera is effective in the management of symptomatic oral lichen planus with minimal side effects.


Keywords


Aloe Vera, Lichen Planus, Erosive, Topical, Systemic.

References





DOI: https://doi.org/10.18311/ijmds%2F2016%2F100595