Open Access Open Access  Restricted Access Subscription Access

Thoracic Epidural Versus General Anaesthesia for MRM Surgeries


Affiliations
1 Department of Anaesthesia, MKCG Medical College and Hospital Brahmpur, Ganjam Odisha-760004, India
 

Background: General anaesthesia is still the preferred technique amongst many practitioners for oncologic breast surgeries. However the TEA technique has a lot of advantages over the conventional GA technique.

Objective: We attempted to evaluate the two techniques of anaesthesia for MRM surgeries.

Materials and Method: Sixty ASA I-II patients undergoing MRM were randomly assigned to two study groups of 30 patients each. In the TEA group (group T), an epidural catheter was inserted at T7-T8 level, and 8-10 ml of 0.5% bupivacaine was titrated and administered. GA (group G) was induced with 2mg/kg of propofol and was maintained with Isoflurane, intermittent inj. Vecuronium and 70% N2O in oxygen. The authors evaluated the adequacy of anesthesia, surgical condition, post anesthetic recovery, post anesthetic analgesia and patients' satisfaction.

Results: The intra operative haemodynamics was comparable in between the two groups. The incidence of nausea and vomiting was significantly lower in the TEA group (16.5% in group T and 39.6% in group G , P = 0.02). The mean immediate VAS score was also lower in TEA group ( group T =2.4 , group G =5.8,P = 0.001). Aldrete recovery score was 9/10 in 1st hr in a significant proportion in the TEA group (89.1% in group T v/s 59.4% in group G , P = 0.003). Patient satisfaction was significantly higher. The surgeons were however satisfied with both the methods.

Conclusion: Use of thoracic epidural technique as a sole anaesthetic technique for MRM surgeries provides adequate operating conditions, better side effect profile, better pain management and patient satisfaction.


Keywords

MRM, Thoracic Epidural, General Anesthesia, Breast Carcinoma.
User
Notifications
Font Size


  • Von Kanel R, Mills PJ, Ziegler MG, Dimsdale JE. Effect of beta2-adrenergic receptor functioning and increased norepinephrine on the hypercoagulable state with mental stress. Am Heart J 2002;144:68-72.
  • Sambola A, Osende J, Hathcock J, Degen M, Nemerson Y, Fuster V, et al. Role of risk factors in the modulation of tissue factor activity and blood thrombogenicity. Circulation 2003; 107(7):973-7.
  • Gidron Y, Gilutz H, Berger R, Huleihel M. Molecular and cellular interface between behavior and acute coronary syndromes. Cardiovasc Res 2002; 56(1):15-21.
  • Waurick R, Van Aken H. Update in thoracic epidural anaesthesia. Best Pract Res Clin Anaesthesiol 2005; 19:201-13.
  • Baron JF, Payen D, Coriat P, Edouard A, Viars P. Forearm vascular tone and reactivity during lumbar epidural anaesthesia. Anesth Analg 1988; 67:1065-70.
  • Andreas Meissner, Lars Eckardt, Paulus Kirchhof, Thomas Weber, Norbert Rolf, Gunter Breithardt, et al. Effects of Thoracic Epidural Anesthesia with and without Autonomic Nervous System Blockade on Cardiac Monophasic Action Potentials and Effective Refractoriness in Awake Dogs. Anesthesiology 2001; 95:132-8.
  • Blomber S, Emmanuel H, Kvist H, Lamm C, Ponten J, Waagstein F, et al. Effects of thoracic epidural anesthesia on coronary arteries and arterioles in patients with coronary artery disease. Anesthesiology 1990;73:840-7.
  • GA McLeod, C Cumming. Thoracic epidural anaesthesia and analgesia. Continuing Education in Anaesthesia, Critical Care & Pain 2004;4(1):16-9.
  • A Clemente, F Carli. The physiological effects of thoracic epidural anesthesia and analgesia on cardiovascular, respiratory and gastrointestinal systems. Minerva Anesthesiol 2008; 74:549-63.
  • Sakura S, Saito Y, Kosaka Y. The effect of epidural anesthesia on ventilatory response to hypercapnia in young and elderly patients. Anesth Analg 1996; 82:306-11.
  • Lynch EP, Welch KJ, Carabuena TM, Eberlein TJ. Thoracic epidural anesthesia improves outcome after breast surgery. Ann Surg 1995 Nov;222(5):663-9.
  • Yeh CC, Yu JC, Wu CT, Ho ST, Chang TM, Wong CS. Thoracic epidural anesthesia for pain relief and postoperation recovery with modified radical mastectomy. World J Surg 1999;23:256- 61.
  • Nabil W Doss, Joseph Ipe, Thomas Crimi, Sanjeev Rajpal, Steven Cohen, Richard J, et al. Continuous Thoracic Epidural Anesthesia with 0.2% Ropivacaine versus General Anesthesia for Perioperative Management of Modified Radical Mastectomy. Anesth Analg 2001;92:1552-7.
  • Borgeat A, Ekatodramis G, Schenker C. Postoperative nausea and vomiting in regional anesthesia: a review. Anesthesiology 2003;98:530-47.
  • Block BM, Liu SS, Rowlingson AJ, Cowan AR, Cowan JA Jr, Wu CL. Efficacy of postoperative epidural analgesia: A metaanalysis. JAMA 2003;290:2455-63.
  • Kroner K, Knudsen UB, Lundby L - Long-term phantom breast syndrome after mastectomy. Clin J Pain 1992; 8:346-50.
  • Liu S, Carpenter RL, Neal JM. Epidural anesthesia and analgesia. Anesthesiology 1995; 82:1474-506.

Abstract Views: 301

PDF Views: 147




  • Thoracic Epidural Versus General Anaesthesia for MRM Surgeries

Abstract Views: 301  |  PDF Views: 147

Authors

S. Lahiry
Department of Anaesthesia, MKCG Medical College and Hospital Brahmpur, Ganjam Odisha-760004, India
D. N. Sharma
Department of Anaesthesia, MKCG Medical College and Hospital Brahmpur, Ganjam Odisha-760004, India
M. Mund
Department of Anaesthesia, MKCG Medical College and Hospital Brahmpur, Ganjam Odisha-760004, India
R. Dhaarini
Department of Anaesthesia, MKCG Medical College and Hospital Brahmpur, Ganjam Odisha-760004, India
H. Deshmukh
Department of Anaesthesia, MKCG Medical College and Hospital Brahmpur, Ganjam Odisha-760004, India

Abstract


Background: General anaesthesia is still the preferred technique amongst many practitioners for oncologic breast surgeries. However the TEA technique has a lot of advantages over the conventional GA technique.

Objective: We attempted to evaluate the two techniques of anaesthesia for MRM surgeries.

Materials and Method: Sixty ASA I-II patients undergoing MRM were randomly assigned to two study groups of 30 patients each. In the TEA group (group T), an epidural catheter was inserted at T7-T8 level, and 8-10 ml of 0.5% bupivacaine was titrated and administered. GA (group G) was induced with 2mg/kg of propofol and was maintained with Isoflurane, intermittent inj. Vecuronium and 70% N2O in oxygen. The authors evaluated the adequacy of anesthesia, surgical condition, post anesthetic recovery, post anesthetic analgesia and patients' satisfaction.

Results: The intra operative haemodynamics was comparable in between the two groups. The incidence of nausea and vomiting was significantly lower in the TEA group (16.5% in group T and 39.6% in group G , P = 0.02). The mean immediate VAS score was also lower in TEA group ( group T =2.4 , group G =5.8,P = 0.001). Aldrete recovery score was 9/10 in 1st hr in a significant proportion in the TEA group (89.1% in group T v/s 59.4% in group G , P = 0.003). Patient satisfaction was significantly higher. The surgeons were however satisfied with both the methods.

Conclusion: Use of thoracic epidural technique as a sole anaesthetic technique for MRM surgeries provides adequate operating conditions, better side effect profile, better pain management and patient satisfaction.


Keywords


MRM, Thoracic Epidural, General Anesthesia, Breast Carcinoma.

References





DOI: https://doi.org/10.18311/ijmds%2F2016%2F100592