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Zns nanoparticles are prepared by chemical coprecipitation method and analysis of antibacterial, antifungal activity against pathogens is established. The artificial production of nanoparticles is investigated by using Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD). It was found that the synthesized ZnS nanoparticles are cubic of high-quality. Moreover, it was analyzed that ZnS optical properties which are related to the environment temperature.