Current Science

Muringayil Joseph Tomy ¹, Chelankara Suresh Sharanya ¹, Abdulhameed Sabu ¹, Madhathil Kovilakathu Haridas ¹

Affiliations
1 Inter University Centre for Bioscience and Department of Biotechnology and Microbiology, Kannur University, Thalassery Campus, Kannur 670 661, IN

Abstract

Fermentative production of benzoic acid is seldom reported and the present report serendipitously expressed it, though in small quantity (~30 mg/l). Lipoxygenases (LOXs) catalyse the stereo-specific insertion of molecular oxygen into arachidonic acid, leading to hydroxy derivatives as end products. Ser-endipitously found LOX inhibitor was benzoic acid, produced in Ayurvedic-fermented medicated wine, pippalyasava. The present study reports the signifi-cance of the polyphenol derivatives in a traditional Ayurvedic therapeutic preparation where LOX inhibi-tion might have a role, besides its importance in fermented benzoic acid production.

Keywords

Ayurvedic-Fermented Wine, Benzoic Acid, Inflammation, Lox Inhibitors, Polyphenol Metabolites.

Full Text