Current Science

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Fermentative production of benzoic acid is seldom reported and the present report serendipitously expressed it, though in small quantity (~30 mg/l). Lipoxygenases (LOXs) catalyse the stereo-specific insertion of molecular oxygen into arachidonic acid, leading to hydroxy derivatives as end products. Ser-endipitously found LOX inhibitor was benzoic acid, produced in Ayurvedic-fermented medicated wine, pippalyasava. The present study reports the signifi-cance of the polyphenol derivatives in a traditional Ayurvedic therapeutic preparation where LOX inhibi-tion might have a role, besides its importance in fermented benzoic acid production.

Keywords

Ayurvedic-Fermented Wine, Benzoic Acid, Inflammation, Lox Inhibitors, Polyphenol Metabolites.
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