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Hepatomyoencephalopathy in Malkangiri District of Odisha, India


Affiliations
1 No. 439, Civil Supplies Godown Lane, Kamalakshipuram, Vellore 632 002, India
2 Manipal Centre for Virus Research, Manipal University, Manipal 576 104, India
3 National Vector Borne Disease Control Programme, Odisha, India
4 CSIR-Indian Institute of Toxicology Research, 31 Vish Vigyan Bhawan, M. G. Marg, Lucknow 226 001, India
 

During September through November 2016, some 100 children died due to acute brain disease in Malkangiri district, southern Odisha, India. Most deaths were at first attributed to Japanese encephalitis (JE) due to the following reasons: JE had been reported in Malkangiri district in previous years and diagnostic test for JE was positive in a few children in 2016; JE season is September through November; the vector mosquitoes and amplifying hosts, namely pigs, are prevalent in Malkangiri district. However, a number of cases turned out negative for JE test. Therefore, in the last week of October, the Department of Health, Government of Odisha, constituted a team to investigate the cases of non-JE acute brain disease with high mortality.
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Abstract Views: 285

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  • Hepatomyoencephalopathy in Malkangiri District of Odisha, India

Abstract Views: 285  |  PDF Views: 88

Authors

T. Jacob John
No. 439, Civil Supplies Godown Lane, Kamalakshipuram, Vellore 632 002, India
G. Arunkumar
Manipal Centre for Virus Research, Manipal University, Manipal 576 104, India
Madan M. Pradhan
National Vector Borne Disease Control Programme, Odisha, India
Mukul Das
CSIR-Indian Institute of Toxicology Research, 31 Vish Vigyan Bhawan, M. G. Marg, Lucknow 226 001, India

Abstract


During September through November 2016, some 100 children died due to acute brain disease in Malkangiri district, southern Odisha, India. Most deaths were at first attributed to Japanese encephalitis (JE) due to the following reasons: JE had been reported in Malkangiri district in previous years and diagnostic test for JE was positive in a few children in 2016; JE season is September through November; the vector mosquitoes and amplifying hosts, namely pigs, are prevalent in Malkangiri district. However, a number of cases turned out negative for JE test. Therefore, in the last week of October, the Department of Health, Government of Odisha, constituted a team to investigate the cases of non-JE acute brain disease with high mortality.

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DOI: https://doi.org/10.18520/cs%2Fv113%2Fi12%2F2245-2246