Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Evaluation of Antimotility Effect of Plumbago indica (L.) on Charcoal Induced Gastrointestinal Motility in Mice


Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh Chittagong, Bangladesh
     

   Subscribe/Renew Journal


Evaluation of antimotility activity was done in intestine of mice treated with methanolic extract of Plumbago indica L. (MEPI).Charcoal was used as a promotility agent. The antimotility activity with the mean defecation period 302.2 and 376.4min at the dose of 250 and 500mg/kg body weight.

Keywords

Plumbago indica L., Gastrointestinal Motility, Chacoal.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Massee B, McGahey C: A Framework for Action; Child Diarrhea Prevention. Global healthlink, a publication of the Global Health Council, www.globalhealth.org 2001., (111):
  • Harrison TR: Diarrhea and Constipation. In Principles of internal medicine. 16th edition. New York: Macgraw Hill; 2005:224-232.
  • Hardman JG, Limbird LE: Goodman's and Gilman's: Drugs affecting gastrointestinal function. In The pharmacological basis of therapeutics. 10th edition. New York: Macgraw Hill; 2001:1023-1024.
  • Chitme HR, Chandra R, Kaushik S: Studies on anti-diarrhoeal activity of Calotropis gigantea R.Br. in experimental animals. J Pharm Pharmaceut Sci 2004, 7:70-75.
  • Van Der Vijver Lm. Distribution of plumbagin in the Plumbaginaceae. Phytochemistry 1974, Vol 11, Pages 3247-3248.
  • Bala Rathinasabapathi, Walid M. Fouad, and Celia A. Sigua . β-Alanine Betaine Synthesis in the Plumbaginaceae. Purification and Characterization of a Trifunctional, S-Adenosyl-l-Methionine-Dependent N-Methyltransferase from Limonium latifolium Leaves. Plant Physiol. 2001, Vol 126(3), Pages 1241-1249.
  • Herida Regina Nunes Marona and Maria Beatriz Bastos LUCCHESI , (2004) , Protocol ofr Refine Intestinal Motility in mice and rats, 38: 257-260.

Abstract Views: 270

PDF Views: 4




  • Evaluation of Antimotility Effect of Plumbago indica (L.) on Charcoal Induced Gastrointestinal Motility in Mice

Abstract Views: 270  |  PDF Views: 4

Authors

Swati Paul
Department of Pharmacy, BGC Trust University Bangladesh Chittagong, Bangladesh
Dibyajyoti Saha
Department of Pharmacy, BGC Trust University Bangladesh Chittagong, Bangladesh

Abstract


Evaluation of antimotility activity was done in intestine of mice treated with methanolic extract of Plumbago indica L. (MEPI).Charcoal was used as a promotility agent. The antimotility activity with the mean defecation period 302.2 and 376.4min at the dose of 250 and 500mg/kg body weight.

Keywords


Plumbago indica L., Gastrointestinal Motility, Chacoal.

References