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Cytotoxic Activity of Ethanol Extract of Leea indica Leaf


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1 Department of Pharmacy, BGC Trust University, Chittagong, Bangladesh
     

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The cytotoxic activity of ethanol extract of Leea indica (Burm. f.) Merr., (Family: Leeaceae) leaf has been investigated in the present study. The cytotoxic activity of the L. indica ethanol extract was assessed by brine shrimp lethality bioassay method. In brine shrimp lethality bioassay LC50 value of L. indica ethanol extract was found 2.4771μg/ml with 95% confidence limit where the lower and upper limits were 2.2561 and 2.6981 μg/ml respectively, which indicates that the leaf extract has promising cytotoxic effect. The present study demonstrates that ethanol extract of L. indica leaf has significant cytotoxic effect.

Keywords

Leea indica, Cytotoxic, Brine Shrimp Lethality Bioassay, LC50.
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  • Cytotoxic Activity of Ethanol Extract of Leea indica Leaf

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Authors

Swati Paul
Department of Pharmacy, BGC Trust University, Chittagong, Bangladesh
Dibyajyoti Saha
Department of Pharmacy, BGC Trust University, Chittagong, Bangladesh

Abstract


The cytotoxic activity of ethanol extract of Leea indica (Burm. f.) Merr., (Family: Leeaceae) leaf has been investigated in the present study. The cytotoxic activity of the L. indica ethanol extract was assessed by brine shrimp lethality bioassay method. In brine shrimp lethality bioassay LC50 value of L. indica ethanol extract was found 2.4771μg/ml with 95% confidence limit where the lower and upper limits were 2.2561 and 2.6981 μg/ml respectively, which indicates that the leaf extract has promising cytotoxic effect. The present study demonstrates that ethanol extract of L. indica leaf has significant cytotoxic effect.

Keywords


Leea indica, Cytotoxic, Brine Shrimp Lethality Bioassay, LC50.