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Spectrophotometric Estimation of Ofloxacin in Pharmaceutical Dosage Form


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1 Department of Pharmaceutical Analysis, A.S.N Pharmacy College, Tenali, Andhra Pradesh
     

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Simple, accurate and rapid Spectrophotometric method was developed for the estimation of ofloxacin in tablet dosage form. The method is based on the absorption of electromagnetic radiation by cefixime at the maximum wavelength at 294 nm in 0.1M Hydrochloric acid as solvent. Beer's law was obeyed in the concentration range of 10-80 μg/ml. The percentage assay for commercial formulation was found to be 100.02± 0.82.Recovery value was found to be 99.95±0.54.

Keywords

Ofloxacin, Spectrophotometric Methods, Statistical Analysis, Recovery Studies
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  • Spectrophotometric Estimation of Ofloxacin in Pharmaceutical Dosage Form

Abstract Views: 316  |  PDF Views: 2

Authors

K. Navyatha
Department of Pharmaceutical Analysis, A.S.N Pharmacy College, Tenali, Andhra Pradesh
P. Jyothi Kanaka Durga
Department of Pharmaceutical Analysis, A.S.N Pharmacy College, Tenali, Andhra Pradesh
B. Lakshmi Madhuri
Department of Pharmaceutical Analysis, A.S.N Pharmacy College, Tenali, Andhra Pradesh
K. Madhavi
Department of Pharmaceutical Analysis, A.S.N Pharmacy College, Tenali, Andhra Pradesh
N. Delhiraj
Department of Pharmaceutical Analysis, A.S.N Pharmacy College, Tenali, Andhra Pradesh

Abstract


Simple, accurate and rapid Spectrophotometric method was developed for the estimation of ofloxacin in tablet dosage form. The method is based on the absorption of electromagnetic radiation by cefixime at the maximum wavelength at 294 nm in 0.1M Hydrochloric acid as solvent. Beer's law was obeyed in the concentration range of 10-80 μg/ml. The percentage assay for commercial formulation was found to be 100.02± 0.82.Recovery value was found to be 99.95±0.54.

Keywords


Ofloxacin, Spectrophotometric Methods, Statistical Analysis, Recovery Studies

References