Asian Journal of Research in Chemistry

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Ethnomedicinal, Phytochemical and Pharmacological properties of Pistacia atlantica Desf. (Anacardiaceae): Review


Affiliations
1 Laboratory of Valorization and Promotion of Saharan Resources VPRS, Department of Chemistry, Faculty of Mathematics and Material Sciences, University of Kasdi Merbah, Ouargla, Algeria., India
     

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Pistacia atlantica belongs to the Anacardiaceae family, it has been widely used in the Middle Eastern and Mediterranean areas since ancient times. Pistacia atlantica has been used for different diseases like stomach, pain, peptic ulcer, wounds, renal disorders, and coughs. This study aims to review its ethnobotanical characterization, traditional uses, phytochemistry, and pharmacological activities found in this plant. The data in this review article was based on electronic databases such as Web of Science, Springer, Yahoo search, Science Direct, PubMed, and Google Scholar for papers published from 2016 until March 2021 are considered. The results showed that Pistacia atlantica has many medicinal properties such as antioxidant, antidiabetic, anticancer, anti-inflammatory, and others. Phytochemical has shown the presence of numerous valuable compounds, including volatile compounds, fatty acids, phenolic compounds, and flavonoids. In this regard, the ethnomedicinal, phytochemistry, biological, and pharmacological properties of Pistacia atlantica have been reviewed here.

Keywords

Pistacia atlantica, Anacardiaceae, traditional use, pharmacological, phytochemical, ethnomedicinal.
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  • A. Rauf, S. Patel, G. Uddin, B.S. Siddiqui, B. Ahmad, N. Muhammad, Y.N. Mabkhot, T.B. Hadda, Phytochemical, ethnomedicinal uses and pharmacological profile of genus Pistacia, Biomedicine & Pharmacotherapy, 86 (2017) 393-404.

  • F. Mahjoub, K.A. Rezayat, M. Yousefi, M. Mohebbi, R. Salari, Pistacia atlantica Desf. A review of its traditional uses, phytochemicals and pharmacology, Journal of medicine and life, 11 (2018) 180.

  • Z.B. Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, Y. Vander Heyden, Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica): A review of their botany, ethnobotany, phytochemistry and pharmacology, Journal of Ethnopharmacology, (2020) 113329.

  • E.Z.-B. Asma, Taxonomic and botanical retrospective review of Pistacia atlantica Desf.(Anacardiaceae), Arabian Journal of Medicinal and Aromatic Plants, 5 (2019) 47-77.

  • A. Labdelli, R. De La Herrán, R. Arafeh, F. Resentini, L. Trainotti, Y. Halis, A. Adda, O. Merah, Genetic Variation in Damaged Populations of Pistacia atlantica Desf, Plants, 9 (2020) 1541.

  • H. Rankou, S. M'SOU, R. Ait Babahmad, A. Ouhammou, M. Alifriqui, G. Martin, Pistacia atlantica, in, The IUCN Red List of Threatened Species, 2018.

  • M. Amara, M. Bouazza, K. Errouane, M. Kaid-Harche, D. Nafil, R. Pascalau, L. Smuleac, M.G. Al-Saghir, Systematic Position of Pistacia atlantica Desf. Subsp. atlantica in North-West Algeria: Anatomy and Biometry of Leaves, Advanced Research in Life Sciences, 4 (2020) 48-53.

  • A. El Zerey-Belaskri, H. Benhassaini, Morphological leaf variability in natural populations of Pistacia atlantica Desf. subsp. atlantica along climatic gradient: new features to update Pistacia atlantica subsp. atlantica key, International journal of biometeorology, 60 (2016) 577-589.

  • A. El Zerey-Belaskri, T. Ribeiro, M.L. Alcaraz, W.E. Zerey, S. Castro, J.Loureiro, H. Benhassaini, J.I. Hormaza, Molecular characterization of Pistacia atlantica Desf. subsp. atlantica (Anacardiaceae) in Algeria: Genome size determination, chromosome count and genetic diversity analysis using SSR markers, Scientia Horticulturae, 227 (2018) 278-287.

  • I. Achili, A. Amrani, C. Bensouici, F. Gül, M. Altun, I. Demirtas, D. Zama, F. Benayache, S. Benayache, Chemical constituents, antioxidant, anticholinesterase and antiproliferative effects of Algerian Pistacia atlantica Desf. extracts, Recent patents on food, nutrition & agriculture, 11 (2020) 249-256.

  • M.D. Miara, I. Teixidor-Toneu, T. Sahnoun, H. Bendif, M.A. Hammou, Herbal remedies and traditional knowledge of the Tuareg community in the region of Illizi (Algerian Sahara), Journal of Arid Environments, 167 (2019) 65-73.

  • M.B. Hmed, H. Alimi, F. Guesmi, F. Elatrech, N. Zouari, Y. Chtourou, R.B.Salem, G. Rigane, S. Cherif, Pistacia atlantica Desf. roots extract: LC-ESIMS Analysis, antioxidant activity and gastroprotective effect on experimentally-induced ultrastructural gastric ulcers in mice, Ultrastructural Pathology, (2021) 1-10.

  • H.S. Rahman, Phytochemical analysis and antioxidant and anticancer activities of mastic gum resin from Pistacia atlantica subspecies kurdica, OncoTargets and therapy, 11 (2018) 4559.

  • P. Gharazi, S. Momtaz, Z. Rezaei, M. Rahimifard, M. Baeeri, A. Abdollahi, M. Abdollahi, K. Zare, M.H. Farzaei, Protective effect of a formulation containing Pistacia atlantica oleo-gum-resin and honey on experimental model of acetic acid-induced colitis in rats, Research Journal of Pharmacognosy, 8 (2021) 37-49.

  • A. Labdelli, K. Zemour, V. Simon, M. Cerny, A. Adda, O. Merah, Pistacia atlantica Desf., a source of healthy vegetable oil, Applied Sciences, 9 (2019) 2552.

  • A. Labdelli, A. Rebiai, M. Tahirine, A. Adda, O. Merah, Nutritional content and antioxidant capacity of the seed and the epicarp in different ecotypes of Pistacia atlantica desf. subsp. atlantica, Plants, 9 (2020) 1065.

  • H.M. Ahmed, Traditional uses of Kurdish medicinal plant Pistacia atlantica subsp. kurdica Zohary in Ranya, Southern Kurdistan, Genetic Resources and Crop Evolution, 64 (2017) 1473-1484.

  • G. Hajjaj, A. Bahlouli, K. Sayah, M. Tajani, Y. Cherrah, A. Zellou, Phytochemical screening and in vivo antipyretic activity of the aqueous extracts of three Moroccan medicinal plants, Pharm. Biol. Eval., 4 (2017) 188-192.

  • M. Chelghoum, H. Guenane, M. Harrat, M. Yousfi, Total Tocopherols, Carotenoids, and Fatty Acids Content Variation of Pistacia atlantica from Different Organs’ Crude Oils and Their Antioxidant Activity during Development Stages, Chemistry & Biodiversity, 17 (2020) e2000117.

  • M. Gharsallaoui, H. Azouzi, A. Chelli-Chaabouni, M. Ghrab, J. Condoret, M. Ayadi, S. Gabsi, Extraction methods of seed oil and oil quality of Pistacia atlantica grown in dry land, in: Options Méditerranéennes. Series A: Mediterranean Seminars, ENA, École Nationale d'Agriculture de Meknès (Morocco); CIHEAM-IAMZ …, 2016.

  • T. Leila, M.E.A. Dib, B. Tabti, C. Jean, A. Muselli, Insecticidal Activity of Essential Oils of Pistacia atlantica Desf. and Pistacia lentiscus L. Against Tribolium confusum Dul, Journal of Applied Biotechnology Reports, 7 (2020) 111-115.

  • S.-M. Hasheminya, J. Dehghannya, Composition, phenolic content, antioxidant and antimicrobial activity of Pistacia atlantica subsp. kurdica hulls’ essential oil, Food Bioscience, 34 (2020) 100510.

  • I. Labed-Zouad, M. Ferhat, M. Öztürk, I. Abaza, S. Nadeem, A. Kabouche, Z. Kabouche, Essential Oils Composition, Anticholinesterase and Antioxidant Activities of Pistacia atlantica Desf, Rec Nat Prod, 11 (2017) 411-415.

  • S. Bagheri, M.M. Sarabi, P. Khosravi, R.M. Khorramabadi, S. Veiskarami, H. Ahmadvand, M. Keshvari, Effects of Pistacia atlantica on oxidative stress markers and antioxidant enzymes expression in diabetic rats, Journal of the American College of Nutrition, 38 (2019) 267-274.

  • A. Sadeghi, M. Pourya, G. Smagghe, Insecticidal activity and composition of essential oils from Pistacia atlantica subsp. kurdica against the model and stored product pest beetle Tribolium castaneum, Phytoparasitica, 44 (2016) 601-607.

  • S.M. Nachvak, S. Hosseini, A. Nili-Ahmadabadi, D. Dastan, M. Rezaei, Chemical composition and antioxidant activity of Pistacia atlantica subsp.Kurdica from Awraman, Journal of Reports in Pharmaceutical Sciences, 7 (2018) 222-230.

  • H. Mahmoudvand, F. Kheirandish, M. Ghasemi Kia, A. Tavakoli Kareshk, M. Yarahmadi, Chemical composition, protoscolicidal effects and acute toxicity of Pistacia atlantica Desf. fruit extract, Natural product research, 30 (2016) 1208-1211.

  • N. Yarahmadi, M. Hojjatoleslamy, L. Sedaghat Boroujeni, Different drying methods of Pistacia Atlantica seeds: Impact on drying kinetics and selected quality properties, Food Science & Nutrition, 8 (2020) 3225-3233.

  • A. El Zerey-Belaskri, C. Cavaleiro, A. Romane, H. Benhassaini, L.Salgueiro, Intraspecific chemical variability of Pistacia atlantica Desf. subsp. atlantica essential oil from Northwest Algeria, Journal of EssEntial oil rEsEarch, 29 (2017) 32-41.

  • S.H. Azeez, S.M. Gaphor, Evaluation of antibacterial effect against Porphyromonas gingivalis and biocompatibility of essential oil extracted from the gum of Pistacia atlantica kurdica, BioMed research international, 2019 (2019).

  • Z. Memariani, M. Sharifzadeh, M. Bozorgi, M. Hajimahmoodi, M.H. Farzaei, M. Gholami, F. Siavoshi, P. Saniee, Protective effect of essential oil of Pistacia atlantica Desf. On peptic ulcer: role of α-pinene, Journal of Traditional Chinese Medicine, 37 (2017) 57-63.

  • M. Rezaie, R. Farhoosh, N. Pham, R.J. Quinn, M. Iranshahi, Dereplication of antioxidant compounds in Bene (Pistacia atlantica subsp. mutica) hull using a multiplex approach of HPLC–DAD, LC–MS and 1H NMR techniques, Journal of pharmaceutical and biomedical analysis, 117 (2016) 352-362.

  • F. Khallouki, A. Breuer, E. Merieme, C.M. Ulrich, R.W. Owen, Characterization and quantitation of the polyphenolic compounds detected in methanol extracts of Pistacia atlantica Desf. fruits from the Guelmim region of Morocco, Journal of pharmaceutical and biomedical analysis, 134 (2017) 310-318.

  • F. Toul, N. Belyagoubi-Benhammou, A. Zitouni, F. Atik-Bekkara, Antioxidant activity and phenolic profile of different organs of Pistacia atlantica Desf. subsp. atlantica from Algeria, Natural product research, 31 (2017) 718-723.

  • H. Benamar, A. Marouf, M. Bennaceur, Phytochemical composition, antioxidant and acetylcholinesterase inhibitory activities of aqueous extract and fractions of Pistacia atlantica subsp. atlantica from Algeria, Journal of Herbs, Spices & Medicinal Plants, 24 (2018) 229-244.

  • O. Amri, A. Zekhnini, A. Bouhaimi, S. Tahrouch, A. Hatimi, Antiinflammatory activity of methanolic extract from Pistacia atlantica desf. leaves, Pharmacognosy Journal, 10 (2018).

  • Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden, Seasonal, gender and regional variations in total phenolic, flavonoid, and condensed tannins contents and in antioxidant properties from Pistacia atlantica ssp. leaves, Pharmaceutical biology, 55 (2017) 1185-1194.

  • N. Tahir, J. Ahmed, H. Azeez, W. Palani, D. Omer, Phytochemical, antibacterial, antioxidant and phytotoxicity screening of the extracts collected from the fruit and root of wild mt. Atlas mastic tree (Pistacia atlantica subsp. Kurdica), Applied ecology and environmental research, 17 (2019) 4417-4429.

  • H. Kordbacheh, F. Eftekhar, S. Ebrahimi, Anti-quorum sensing activity of Pistacia atlantica against Pseudomonas aeruginosa PAO1 and identification of its bioactive compounds, Microbial pathogenesis, 110 (2017) 390-398.

  • S.A.A. Hussein, A. El-Mesallamy, S.O. Othman, A.e.-M.M. Soliman, Identification of Novel Polyphenolic Secondary Metabolites from Pistacia Atlantica Desf. and Demonstration of their Cytotoxicity and CCl4 induced Hepatotoxicity in Rat, Egyptian Journal of Chemistry, 63 (2020) 117-127.

  • S. Othman, M. El-Hashash, S. Hussein, A. El-Mesallamy, S. Rizk, F.A.Elabbar, Phenolic Content as Antioxidant and Antimicrobial Activities of Pistacia atlantica Desf.(Anacardiaceae) Extract from Libya, Egyptian Journal of Chemistry, 62 (2019) 21-28.

  • Z.B. Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden, Antioxidant activities of Pistacia atlantica extracts modeled as a function of chromatographic fingerprints in order to identify antioxidant markers, Microchemical journal, 128 (2016) 208-217.

  • A.A. Hatamnia, A. Rostamzad, M. Hosseini, N. Abbaspour, R. Darvishzadeh, P. Malekzadeh, B.M. Aminzadeh, Antioxidant capacity and phenolic composition of leaves from 10 Bene (Pistacia atlantica subsp.kurdica) genotypes, Natural product research, 30 (2016) 600-604.

  • F. Toul, N. Belyagoubi-Benhammou, A. Zitouni, N. Ghembaza, F. AtikBekkara, T.A. Imama, IN-VITRO ANTIOXIDANT EFFECTS OF TANNIN EXTRACTS OF PISTACIA ATLANTICA, International Journal of Pharmaceutical Sciences and Research, 7 (2016) 121.

  • H. Barzegar, M. Hojjati, M. Panahi, Antioxidant and antimicrobial activity of different extracts of Pistacia atlantica leaf, (2017).

  • S. Alidadi, M.-T. Moradi, M. Asadi-Samani, Z. Lorigooini, Antioxidant potential and total phenolic compounds of extracts and fractions of Pistasia atlantica, Int J Pharm Clin Res, 9 (2017) 293-297.

  • A. Fatima, T. Mohamed, A. Abdelkader, T.A. Faiza, Phytochemical screening and evaluation of the antioxidant activity of essential oil of Pistacia atlantica harvested from the ouled Brahim region, Saida; Algeria, South Asian Journal of Experimental Biology, 8 (2018) 202-206.

  • J. Tavakoli, K.H. Soq, A. Yousefi, P. Estakhr, M. Dalvi, A.M. Khaneghah, Antioxidant activity of Pistacia atlantica var mutica kernel oil and it’s unsaponifiable matters, Journal of food science and technology, 56 (2019) 5336-5345.

  • M. Fathollahi, M. Aminzare, M. Mohseni, H. Hassanzadazar, Antioxidant capacity, antimicrobial activities and chemical composition of Pistacia atlantica subsp. kurdica essential oil, in: Veterinary Research Forum, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran, 2019, pp.299.

  • C. Bakka, M. Hadjadj, O. Smara, H. Dendougui, S. Mahdjar, In vitro antioxidant activities and total phenolic content of extracts from Pistacia atlantica desf, Journal of Pharmaceutical Sciences and Research, 11 (2019) 3634-3637.

  • Z. Khiya, Y. Oualcadi, A. Gamar, S. Amalich, F. Berrekhis, T. Zair, F.E.Hilali, In vitro Evaluation of Antioxidant Activity of the Methanol and Ethanol Extracts of Pistacia atlantica Desf from Morocco, Phytothérapie, 17 (2019) 321-333.

  • F. Hefied, Z. Ben Ahmed, M. Yousfi, In vitro antioxidant and α‐amylase inhibitory potential of methanolic and lipid fractions from Pistacia atlantica Desf. galls, Journal of Food Processing and Preservation, (2020) e14956.

  • A. Karimi, M.T. Moradi, A. Gafourian, In vitro anti-adenovirus activity and antioxidant potential of Pistacia atlantica Desf. leaves, Research Journal of Pharmacognosy (RJP), 7 (2020).

  • M.A. Roozegar, F.A. Jalilian, M.R. Havasian, J. Panahi, I. Pakzad, Antimicrobial effect of Pistacia atlantica leaf extract, Bioinformation, 12 (2016) 19.

  • G. Rigane, H. Ghazghazi, C. Aouadhi, R. Ben Salem, Z. Nasr, Phenolic content, antioxidant capacity and antimicrobial activity of leaf extracts from Pistacia atlantica, Natural product research, 31 (2017) 696-699.

  • B. Doosti, The comparison of antibacterial and antifungal effects of Pistacia atlantica gum with some inuse antibiotics, Journal of Cellular and Molecular Research (Iranian Journal of Biology), 32 (2019) 115-124.

  • M. Ranjbar, M.H. Azizi, A. Mirmajidi Hashtjin, Evaluation of physicomechanical and antimicrobial properties of gelatin-carboxymethyl cellulose film containing essential oil of bane (Pistacia atlantica), Nutrition and Food Sciences Research, 4 (2017) 11-17.

  • A.H. Barzinji, K. Dzaye, Antimicrobial Effect of Pistacia Atlantica Kurdica as an Intra Canal Medicament in Root Canal Treatment on Enterococcus Fecalis, Annals of the Romanian Society for Cell Biology, (2021) 84858492.

  • F. Benabdallah, M. El Bentchikou, A. Zellagui, N. Gherraf, Ethnobotanical and phytochemical studies and assessment of antimicrobial activity of the leaves of pistachio oleoresin of the atlas (Pistacia atlantica Desf.), Phytothé rapie, (2017).

  • F. AAla, S. Khodaveisi, E. Baghdadi, S. Rezaei, The antifungal effect of Pistacia Atlantica subsp. Kurdica on the growth of Aspergillus parasiticus, Journal of School of Public Health and Institute of Public Health Research, 13 (2016) 79-84.

  • M. Mohammadzadeh, F. Babaeifar, F. Babaei, Combination thrapy of hydroalcoholic extract of Pistacia atlantica kurdica and fluvoxamine on spatial memory of immobilization rat, Journal of Gorgan University of Medical Sciences, 19 (2017) 24-31.

  • A. Aleebrahim, I. Nabipour, Ethnopharmacology of Medicinal Plants in the Kangan-Asaluyeh Area, ISMJ, 21 (2018) 409-428.

  • Z.B. Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D.Mangelings, Y. Vander Heyden, Potentially antidiabetic and antihypertensive compounds identified from Pistacia atlantica leaf extracts by LC fingerprinting, Journal of pharmaceutical and biomedical analysis, 149 (2018) 547-556.

  • M.A. Behmanesh, S.M. Poormoosavi, Pistacia atlantica's effect on ovary damage and oxidative stress in streptozotocin-induced diabetic rats, JBRA assisted reproduction, 25 (2021) 28.

  • S. Hosseini, A. Nili-Ahmadabadi, S.M. Nachvak, D. Dastan, S. Moradi, H.Abdollahzad, R. Mostafai, Antihyperlipidemic and antioxidative properties of pistacia atlantica subsp. Kurdica in streptozotocin-induced diabetic mice, Diabetes, metabolic syndrome and obesity: targets and therapy, 13 (2020) 1231.

  • K. Solati, M. Karimi, M. Rafieian-Kopaei, N. Abbasi, S. Abbaszadeh, M.Bahmani, Phytotherapy for wound healing: The most important herbal plants in wound healing based on iranian ethnobotanical documents, Mini reviews in medicinal chemistry, 21 (2021) 500-519.

  • S.A. Hamidi, A.T. Naeini, A. Oryan, M.R. Tabandeh, N. Tanideh, S. Nazifi, Cutaneous wound healing after topical application of pistacia atlantica gel formulation in rats, Turkish Journal of Pharmaceutical Sciences, 14 (2017) 65.

  • S. Fakour, S. Heydari, L. Akradi, A. Rahimi, Effect of Pistacia atlantica mastic extract on experimental wound healing and various biochemical parameters of blood serum in rabbit models, , دارویی گیاهان پژوهشی علمی فصلنامه 16 (2017) 78-91.

  • M. Mehrabani, S.M. Seyyedkazemi, M.H. Nematollahi, E. Jafari, M. Mehrabani, M. Mehdipour, Z. Sheikhshoaee, A. Mandegary, Accelerated burn wound closure in mice with a new formula based on traditional medicine, Iranian Red Crescent Medical Journal, 18 (2016).

  • F.S. Bonab, M.R. Farahpour, Topical co-administration of Pistacia atlantica hull and Quercus infectoria gall hydroethanolic extract improves woundhealing process, Comparative Clinical Pathology, 26 (2017) 885-892.

  • N. Tanideh, M. Davarmanesh, A. Andisheh‐Tadbir, Z. Ranjbar, P. Mehriar, O. Koohi‐Hosseinabadi, Healing acceleration of oral mucositis induced by 5‐fluorouracil with Pistacia atlantica (bene) essential oil in hamsters, Journal of Oral Pathology & Medicine, 46 (2017) 725-730.

  • E. Heidarian, E. Jafari-Dehkordi, P. Valipour, K. Ghatreh-Samani, L.Ashrafi-Eshkaftaki, Nephroprotective and anti-inflammatory effects of Pistacia atlantica leaf hydroethanolic extract against gentamicin-induced nephrotoxicity in rats, Journal of dietary supplements, 14 (2017) 489-502.

  • C. Bakka, O. Smara, M. Hadjadj, H. Dendougui, S. Mahdjar, A. Benzid, In vitro Anti-inflammatory activity of Pistacia atlantica Desf. extracts, Asian Journal of Research in Chemistry, 12 (2019) 322-325.

  • Z. Shakarami, H.E.G. Ghaleh, B.M. Motlagh, A. Sheikhian, B.J. Kondori, Evaluation of the protective and therapeutic effects of Pistacia atlantica gum aqueous extract on cellular and pathological aspects of experimental asthma in Balb/c mice, Avicenna journal of phytomedicine, 9 (2019) 248.

  • N. Tanideh, A.A. Zareh, M.M. Fani, Evaluation of the Effect of a Topical Gel Form of Pistacia Atlantica and Trachyspermum Ammi on Induced Oral Mucositis in Male Golden Hamsters by Bio-Marker Indices and

  • Stereological Assessment, Journal of Dentistry, 20 (2019) 240.

  • M. Minaiyan, F. Karimi, A. Ghannadi, Anti-inflammatory effect of Pistacia atlantica subsp. kurdica volatile oil and gum on acetic acid-induced acute colitis in rat, Research Journal of Pharmacognosy, 2 (2015) 1-12.

  • G. Hajjaj, A. Bahlouli, M. Tajani, Y. Cherrah, A. Zellou, In vivo analgesic and anti-inflammatory properties of the aqueous extract of Pistacia atlantica Desf. from Morocco, Journal of Ayurvedic and Herbal Medicine, 3 (2017) 196-199.

  • D. Pranitha, M.R. Ch, Inflammation lowering property of pistacia atlantica in cotton pellet granuloma, International Journal of Review in Life Sciences, 9 (2019) 14-17.

  • L. Hashemi, M. Asadi-Samani, M.-T. Moradi, S. Alidadi, Anticancer activity and phenolic compounds of Pistacia atlantica extract, International Journal of Pharmaceutical and Phytopharmacological Research, 7 (2017) 26-31.

  • Y. Rahbar Saadat, A. Barzegari, S. Zununi Vahed, N. Saeedi, M. Eskandani, Y. Omidi, J. Barar, Cyto/genotoxic effects of Pistacia atlantica resin, a traditional gum, DNA and cell biology, 35 (2016) 261-266.

  • Z. Jaafari-Ashkvandi, S.Y. Shirazi, S. Rezaeifard, A. Hamedi, N. Erfani, Cytotoxic effects of Pistacia atlantica (Baneh) fruit extract on human KB cancer cell line, ACTA MEDICA, 62 (2019) 30-34.

  • H. Pasban-Aliabadi, Effects of Baneh (Pistacia atlantica) Gum on Human Breast Cancer Cell Line (MCF-7) and Its Interaction with Anticancer Drug Doxorubicin, Iranian journal of pharmaceutical research: IJPR, 18 (2019) 1959.

  • M. Zibaei, R. Rostamipour, H. Nayebzadeh, Effect of Pistacia atlantica fruit and leaf extracts on hydatid cyst protoscolices, Recent patents on antiinfective drug discovery, 11 (2016) 53-58.

  • S. Nadri, H. Mahmoudvand, H. Mahmoudvand, M. Rashnoo, M. Khaksarian, Chemical composition, antinociceptive and acute toxicity of Pistacia atlantica fruit extract, Entomol Appl Sci Letters, 5 (2018) 8-12.

  • H.O. Dyary, H.S. Rahman, H.H. Othman, S.M.A. Hassan, R. Abdullah, Acute toxicity of Pistacia atlantica green seeds on Sprague-Dawley rat model, J Zankoy Sulaimani, 19 (2017) 9-16.


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  • Ethnomedicinal, Phytochemical and Pharmacological properties of Pistacia atlantica Desf. (Anacardiaceae): Review

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Authors

Chahrazad Bakka
Laboratory of Valorization and Promotion of Saharan Resources VPRS, Department of Chemistry, Faculty of Mathematics and Material Sciences, University of Kasdi Merbah, Ouargla, Algeria., India
Ouanissa Smara
Laboratory of Valorization and Promotion of Saharan Resources VPRS, Department of Chemistry, Faculty of Mathematics and Material Sciences, University of Kasdi Merbah, Ouargla, Algeria., India
Hocine Dendougui
Laboratory of Valorization and Promotion of Saharan Resources VPRS, Department of Chemistry, Faculty of Mathematics and Material Sciences, University of Kasdi Merbah, Ouargla, Algeria., India
Mohamed Hadjadj
Laboratory of Valorization and Promotion of Saharan Resources VPRS, Department of Chemistry, Faculty of Mathematics and Material Sciences, University of Kasdi Merbah, Ouargla, Algeria., India

Abstract


Pistacia atlantica belongs to the Anacardiaceae family, it has been widely used in the Middle Eastern and Mediterranean areas since ancient times. Pistacia atlantica has been used for different diseases like stomach, pain, peptic ulcer, wounds, renal disorders, and coughs. This study aims to review its ethnobotanical characterization, traditional uses, phytochemistry, and pharmacological activities found in this plant. The data in this review article was based on electronic databases such as Web of Science, Springer, Yahoo search, Science Direct, PubMed, and Google Scholar for papers published from 2016 until March 2021 are considered. The results showed that Pistacia atlantica has many medicinal properties such as antioxidant, antidiabetic, anticancer, anti-inflammatory, and others. Phytochemical has shown the presence of numerous valuable compounds, including volatile compounds, fatty acids, phenolic compounds, and flavonoids. In this regard, the ethnomedicinal, phytochemistry, biological, and pharmacological properties of Pistacia atlantica have been reviewed here.

Keywords


Pistacia atlantica, Anacardiaceae, traditional use, pharmacological, phytochemical, ethnomedicinal.

References