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Synthesis, Characterization, UTI and Antibacterial Activity of Schiff Base, (E)-2-(decan-2-ylidene) hydrazine-1-carboxamide Co2+, Mn2+ and Fe3+Metal Complexes


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1 Department of Chemistry, Banasthali Vidyapith, Tonk – Newai, Rajasthan – 304022, India
     

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Novel coordination complexes of Co, Mn and Fe with Azomethine (E)-2-(decan-2-ylidene) hydrazine-1- carboxamide have been synthesized and studied using elemental analysis (C, H, N), FT-IR, 1HNMR, 13 CNMR, XRD and Mass spectroscopy as well as thermal studies. The Schiff base has octahedral geometry and functions as a tridentate ONS donor ligand. The antimicrobial action of the Azomethine ligand and complexes was investigated towards Staphylococcus aureus, Escherichia coli and fungi C. albicans and A. fumigatus. Microbial pathogens invading the urinary tract produced urinary tract infections, they can cause a variety of clinical symptoms as well as potentially fatal sequelae. The current research focus on the growth of a novel antimicrobial agent towards E. coli, P. aeruginosa, K. pneumoniae bacteria.

Keywords

Schiff bases, IR spectra, NMR spectra, Mass spectra, Anti-microbial and UTI activity.
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  • Synthesis, Characterization, UTI and Antibacterial Activity of Schiff Base, (E)-2-(decan-2-ylidene) hydrazine-1-carboxamide Co2+, Mn2+ and Fe3+Metal Complexes

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Authors

Anita
Department of Chemistry, Banasthali Vidyapith, Tonk – Newai, Rajasthan – 304022, India
Priyanka Ghanghas
Department of Chemistry, Banasthali Vidyapith, Tonk – Newai, Rajasthan – 304022, India
Kavita Poonia
Department of Chemistry, Banasthali Vidyapith, Tonk – Newai, Rajasthan – 304022, India

Abstract


Novel coordination complexes of Co, Mn and Fe with Azomethine (E)-2-(decan-2-ylidene) hydrazine-1- carboxamide have been synthesized and studied using elemental analysis (C, H, N), FT-IR, 1HNMR, 13 CNMR, XRD and Mass spectroscopy as well as thermal studies. The Schiff base has octahedral geometry and functions as a tridentate ONS donor ligand. The antimicrobial action of the Azomethine ligand and complexes was investigated towards Staphylococcus aureus, Escherichia coli and fungi C. albicans and A. fumigatus. Microbial pathogens invading the urinary tract produced urinary tract infections, they can cause a variety of clinical symptoms as well as potentially fatal sequelae. The current research focus on the growth of a novel antimicrobial agent towards E. coli, P. aeruginosa, K. pneumoniae bacteria.

Keywords


Schiff bases, IR spectra, NMR spectra, Mass spectra, Anti-microbial and UTI activity.

References