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Synthesis and Antioxidant Activity of Some Flavone Derivatives


Affiliations
1 School of Life Sciences, Swami Ramanand Teerth Marathawada University, Nanded-431606, India
2 Department of Microbiology, Dyanopasak Mahavidyalaya, Parbhani-431401, India
     

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Some novel flavones were synthesized by condensation reactions of substituted ketones with substituted aldehydes to form chalcones. The formed 2-hydroxyl substituted chalcone made to react with polyethylene glycol-400 (PEG-400) with catalytic amount of iodine, produces flavone derivatives. The synthesized derivatives were characterized by spectral analysis and revealed to be therapeutically active as antioxidant agents.

Keywords

Synthesis, Flavones, Antioxidant Activity.
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  • Synthesis and Antioxidant Activity of Some Flavone Derivatives

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Authors

Chandrahas N. Khobragade
School of Life Sciences, Swami Ramanand Teerth Marathawada University, Nanded-431606, India
Ragini G. Bodade
School of Life Sciences, Swami Ramanand Teerth Marathawada University, Nanded-431606, India
Anand V. Manwar
Department of Microbiology, Dyanopasak Mahavidyalaya, Parbhani-431401, India

Abstract


Some novel flavones were synthesized by condensation reactions of substituted ketones with substituted aldehydes to form chalcones. The formed 2-hydroxyl substituted chalcone made to react with polyethylene glycol-400 (PEG-400) with catalytic amount of iodine, produces flavone derivatives. The synthesized derivatives were characterized by spectral analysis and revealed to be therapeutically active as antioxidant agents.

Keywords


Synthesis, Flavones, Antioxidant Activity.