Synthesis and Antioxidant Potential of Novel 2-Isoxazole Substituted Chromenones Synthesized by Microwave Irradiation

Deepti Dongarwar Inamdar; Afeez M. Dinakaran; Vadiraj D. Kurdekar; Hemant R. Jadhav

Vol 3, No 1 (2010)
Pages: 106-109
Published: 2010-03-01

Synthesis and Antioxidant Potential of Novel 2-Isoxazole Substituted Chromenones Synthesized by Microwave Irradiation

Deepti Dongarwar Inamdar , Afeez M. Dinakaran , Vadiraj D. Kurdekar , Hemant R. Jadhav

Affiliations
1 Pharmacy Group, Birla Institute of Technology and Science, Pilani-333031, Rajasthan, India

Novel series of substituted 2-[3-(2,6-halophenyl)-5-methyl-isoxazolyl]-chromen-4-ones were synthesized by microwave irradiation method. The antioxidant activity of the synthesized compounds 5a-j was evaluated using free radical scavenging method (DPPH method) and reducing power assay. The antioxidant activity of synthesized chromenones with respect to the standard used, ascorbic acid is reported here.