Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Validated Spectroscopic Method for Estimation of Aceclofenac from Tablet Formulation


Affiliations
1 Government College of Pharmacy, Karad-415124, Dist Satara, M.S, India
     

   Subscribe/Renew Journal


Aceclofenac is a non steroidal anti-inflammatory drug with good analgesic and anti-rheumatic properties. Various methods for analysis of the same are available but are time consuming and expensive. Here we have developed a new, precise and simple UV spectrophotometric method for estimation of aceclofenac from tablet formulation. The drug obeyed the Beer’s law and showed good correlation. Absorption maxima of aceclofenac in methanol diluted with glass double distilled water was found to be at 273 nm. Beer’s law was obeyed in concentration range 2-20 mcg/ml. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be simple, accurate, precise, economical and robust.

Keywords

Aceclofenac, UV-Spectrophotometry, Recovery, Accuracy.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 161

PDF Views: 0




  • Validated Spectroscopic Method for Estimation of Aceclofenac from Tablet Formulation

Abstract Views: 161  |  PDF Views: 0

Authors

Deepali Gharge
Government College of Pharmacy, Karad-415124, Dist Satara, M.S, India
Pallavi Salve
Government College of Pharmacy, Karad-415124, Dist Satara, M.S, India
Chandrakant Raut
Government College of Pharmacy, Karad-415124, Dist Satara, M.S, India
Chottaram Seervi
Government College of Pharmacy, Karad-415124, Dist Satara, M.S, India
Kundan Pawar
Government College of Pharmacy, Karad-415124, Dist Satara, M.S, India
Pandurang Dhabale
Government College of Pharmacy, Karad-415124, Dist Satara, M.S, India

Abstract


Aceclofenac is a non steroidal anti-inflammatory drug with good analgesic and anti-rheumatic properties. Various methods for analysis of the same are available but are time consuming and expensive. Here we have developed a new, precise and simple UV spectrophotometric method for estimation of aceclofenac from tablet formulation. The drug obeyed the Beer’s law and showed good correlation. Absorption maxima of aceclofenac in methanol diluted with glass double distilled water was found to be at 273 nm. Beer’s law was obeyed in concentration range 2-20 mcg/ml. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be simple, accurate, precise, economical and robust.

Keywords


Aceclofenac, UV-Spectrophotometry, Recovery, Accuracy.