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Synthesis and Biological Activity of N-(1-Alkyl-4-Phenyl-6-Thioxo-1, 6-Dihydro-1, 3, 5-Triazine-2-Yl)-N-Arylidine Hydrazine


Affiliations
1 Saroj Institute of Tech. and Management, Lucknow-226002, India
2 Harish Chandra P.G. College, Varanasi, India
     

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Triazine, arylidinehydrazones were synthesized starting from benzoyl isothiocyanate were condensed with S-benzyl isothiourea which were further reacted with hydrazine to give s-triazynyl hydrazines. These were further reacted with different aromatic aldehydes to give the corresponding hydrazones. The structures of the compounds were confirmed by elemental analysis and spectral studies. In-vitro antibacterial testing was done by serial dilution method.

Keywords

1, 3, 5 Triazine, Hydrazines, Antibacterial.
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  • Synthesis and Biological Activity of N-(1-Alkyl-4-Phenyl-6-Thioxo-1, 6-Dihydro-1, 3, 5-Triazine-2-Yl)-N-Arylidine Hydrazine

Abstract Views: 152  |  PDF Views: 0

Authors

S. N. Pandeya
Saroj Institute of Tech. and Management, Lucknow-226002, India
Vaishali Mishra
Harish Chandra P.G. College, Varanasi, India
Alka Pandey
Harish Chandra P.G. College, Varanasi, India
Ritu Srivastava
Harish Chandra P.G. College, Varanasi, India

Abstract


Triazine, arylidinehydrazones were synthesized starting from benzoyl isothiocyanate were condensed with S-benzyl isothiourea which were further reacted with hydrazine to give s-triazynyl hydrazines. These were further reacted with different aromatic aldehydes to give the corresponding hydrazones. The structures of the compounds were confirmed by elemental analysis and spectral studies. In-vitro antibacterial testing was done by serial dilution method.

Keywords


1, 3, 5 Triazine, Hydrazines, Antibacterial.