Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Synthon Approach in Designing Organic Synthesis


Affiliations
1 Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, Maharashtra, India
2 Dr. D.Y. Patil College of Pharmacy, Akurdi, Pune-411044, Maharashtra, India
     

   Subscribe/Renew Journal


Synthon approach is a very useful analytical tool. It is an analytical approach to Organic Synthesis in which the target molecule is broken into fragments through a series of logical disconnection to get the best plausible and likely starting materials (ie. synthons or building blocks) for the target molecule. Synthesis is the real test of the organic medicinal chemist to use and control organic reactions. In each case the starting material is converted to some desired compound, the target molecule through some key intermediate. Actually, a number of synthetic routes can be written for a given target molecule. But in actual synthesis, generally that route is selected which is economical, safe, and easy to carry out and produces maximum yield in a short reaction time.

Keywords

Synthon Approach, Synthon, Disconnection Rules.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 151

PDF Views: 0




  • Synthon Approach in Designing Organic Synthesis

Abstract Views: 151  |  PDF Views: 0

Authors

A. A. Kulkarni
Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, Maharashtra, India
S. R. Doshi
Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, Maharashtra, India
R. K. Nanda
Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, Maharashtra, India
N. R. Chatterjee
Dr. D.Y. Patil College of Pharmacy, Akurdi, Pune-411044, Maharashtra, India

Abstract


Synthon approach is a very useful analytical tool. It is an analytical approach to Organic Synthesis in which the target molecule is broken into fragments through a series of logical disconnection to get the best plausible and likely starting materials (ie. synthons or building blocks) for the target molecule. Synthesis is the real test of the organic medicinal chemist to use and control organic reactions. In each case the starting material is converted to some desired compound, the target molecule through some key intermediate. Actually, a number of synthetic routes can be written for a given target molecule. But in actual synthesis, generally that route is selected which is economical, safe, and easy to carry out and produces maximum yield in a short reaction time.

Keywords


Synthon Approach, Synthon, Disconnection Rules.