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Synthesis and Characterization of Spirochromanoid Chalcone Derivatives


Affiliations
1 Research Lab. of Pure and Applied Chemistry, Maharashtra Mahavidhyalaya, Nilanga (MS), India
2 Department of Chemistry, Shivneri Mahavidhyalaya, Shirur Anantpal (MS), India
3 OCT Division, National Chemical Lab., Pune (MS), India
     

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The chalcone derivatives of spirochromanoid frame have been synthesized starting from resorcinol. It is converted in to the spirochomanone protected by N-Boc-4-piperidone. The chalcones of this spirochromanone are synthesized by Claisen Schmidt condensation reacting with 2-chloro benzaldehyde, 2-fluro benzaldehyde, 4-methoxy benzaldehyde, 2,4-dimethoxy benzaldehyde, Benzo-1,3-dioxole-5-carbaldehyde. They are further characterized by their IR, NMR, C13, Depth analysis.

Keywords

Spirochromanones, Chalcones, N-Boc-4-Piperidone.
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  • Synthesis and Characterization of Spirochromanoid Chalcone Derivatives

Abstract Views: 180  |  PDF Views: 0

Authors

J. K. Dawale
Research Lab. of Pure and Applied Chemistry, Maharashtra Mahavidhyalaya, Nilanga (MS), India
A. S. Bondge
Department of Chemistry, Shivneri Mahavidhyalaya, Shirur Anantpal (MS), India
P. K. Tripathi
OCT Division, National Chemical Lab., Pune (MS), India
M. M. Krishnan
OCT Division, National Chemical Lab., Pune (MS), India

Abstract


The chalcone derivatives of spirochromanoid frame have been synthesized starting from resorcinol. It is converted in to the spirochomanone protected by N-Boc-4-piperidone. The chalcones of this spirochromanone are synthesized by Claisen Schmidt condensation reacting with 2-chloro benzaldehyde, 2-fluro benzaldehyde, 4-methoxy benzaldehyde, 2,4-dimethoxy benzaldehyde, Benzo-1,3-dioxole-5-carbaldehyde. They are further characterized by their IR, NMR, C13, Depth analysis.

Keywords


Spirochromanones, Chalcones, N-Boc-4-Piperidone.