Asian Journal of Pharmacy and Technology

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Formulation and Evaluation of Controlled Release Tablets of Aspirin


Affiliations
1 Department of Pharmaceutics, Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad, Telangana-500014, India
2 Department of Pharmacognosy, Princeton College of Pharmacy, Korremula, Ghatkesar, R. R. District, Telangana-500088, India
3 Department of Pharmaceutical Technology, Netaji Institute of Pharmaceutical Sciences, Toopranpet, Yadadri Bhongir, Telangana-508252, India
4 Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, Newmallepally, Hyderabad, Telangana, India
     

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The present work was aimed to develop controlled release tablets of aspirin. Direct compression technique was adopted for the preparation of all these formulations. The developed tablets were evaluated for pre compression parameters; post compression parameters, in vitro dissolution study. Among all the developed batches ASF3 showed highest drug release 96.14% at the end of 10 h. The optimized formulation was found to be stable up to 3 months when tested for stability study at 40±2ºC/ 75±5% RH.

Keywords

Aspirin, Direct Compression, in vitro Drug Release, Stability Study.
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  • Sahoo CK,Rao SRM,Sudhakar M., Shashikala P,Formulation and Optimization of Controlled Porosity Osmotic Pump Tablets of Ritonavir, Journal of Chemical and Pharmaceutical Sciences, 2017; 10(3):1345-1352.


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  • Formulation and Evaluation of Controlled Release Tablets of Aspirin

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Authors

Chinmaya Keshari Sahoo
Department of Pharmaceutics, Malla Reddy College of Pharmacy, Maisammaguda, Secunderabad, Telangana-500014, India
K. Satyanarayana
Department of Pharmacognosy, Princeton College of Pharmacy, Korremula, Ghatkesar, R. R. District, Telangana-500088, India
D. Venkata Ramana
Department of Pharmaceutical Technology, Netaji Institute of Pharmaceutical Sciences, Toopranpet, Yadadri Bhongir, Telangana-508252, India
Kanhu Charan Panda
Department of Pharmaceutics, Anwarul Uloom College of Pharmacy, Newmallepally, Hyderabad, Telangana, India

Abstract


The present work was aimed to develop controlled release tablets of aspirin. Direct compression technique was adopted for the preparation of all these formulations. The developed tablets were evaluated for pre compression parameters; post compression parameters, in vitro dissolution study. Among all the developed batches ASF3 showed highest drug release 96.14% at the end of 10 h. The optimized formulation was found to be stable up to 3 months when tested for stability study at 40±2ºC/ 75±5% RH.

Keywords


Aspirin, Direct Compression, in vitro Drug Release, Stability Study.

References