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A Review on Curcumin Nanoparticles and its Controlled Delivery to Treat Degenerative Diseases


Affiliations
1 Department of Biotechnology, Sri Venkateswara College of Engineering, Irungattukottai, Sriperumbudur-602117, India
2 Department of Biotechnology, Sri Venkateswara College of Engineering, Pennalur Irungattukottai, Sriperumbudur-602117, India
     

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Curcumin is the principle component found in turmeric. It is a well reputed anti-oxidant. It also exhibits anticancerous, anti-inflammatory and anti-tumor activities. However their introduction into the clinical setting is hindered largely due to their poor solubility and rapid metabolism, which ultimately results in poor bioavailability upon oral administration. Therefore green nanotechnology provides a solution towards increased bioavailability of curcumin. Drug delivery systems such as nanoparticles, micro emulsions, liposomes and blocking the degradable sites sustains the efficacy of curcumin. This article focuses on the different forms of nanoparticle drug delivery system carried out on curcumin and its potential uses in treating degenerative diseases.
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  • A Review on Curcumin Nanoparticles and its Controlled Delivery to Treat Degenerative Diseases

Abstract Views: 287  |  PDF Views: 0

Authors

G. Sweetha
Department of Biotechnology, Sri Venkateswara College of Engineering, Irungattukottai, Sriperumbudur-602117, India
B. Sangeetha
Department of Biotechnology, Sri Venkateswara College of Engineering, Irungattukottai, Sriperumbudur-602117, India
S. Prabhu
Department of Biotechnology, Sri Venkateswara College of Engineering, Pennalur Irungattukottai, Sriperumbudur-602117, India

Abstract


Curcumin is the principle component found in turmeric. It is a well reputed anti-oxidant. It also exhibits anticancerous, anti-inflammatory and anti-tumor activities. However their introduction into the clinical setting is hindered largely due to their poor solubility and rapid metabolism, which ultimately results in poor bioavailability upon oral administration. Therefore green nanotechnology provides a solution towards increased bioavailability of curcumin. Drug delivery systems such as nanoparticles, micro emulsions, liposomes and blocking the degradable sites sustains the efficacy of curcumin. This article focuses on the different forms of nanoparticle drug delivery system carried out on curcumin and its potential uses in treating degenerative diseases.