Immunomodulatory Activity of Balanite roxburghi

Besides having traditional use as an im munomodulatory action, it is not well scientifically establish. Hence present study was undertaken to screen the immunomodulatory activity of ethanolic extract of Balanite roxburghi leaves. Traditionally, leaves of Balanite roxburghi are claimed to possess immunomodulatory activity and hence the reason behind evaluating the immunomodulatory activity of ethanolic extract of Balanite roxburghi (EBR) leaves . The animals were distributed into three groups consisting of six animals each. The first group served as control, the second and third group received low dose and high dose of ethanolic extract of Balanite roxburghi (EBR) at 200 mg/kg, p.o. and 400 mg/kg, p.o. respectively. The immunomodulatory activity of EBR was evaluated in Carbon clearance test, Effect on serum immunoglobulin, Cyclophosphamide induced neutropenia. In all these paradigms 400mg/kg dose of EBR was more effective than its 200 mg/kg of dose. These results suggest that Balanite roxburghi can be use as immunomodulator.