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Akanksha, Choudhary
- A Case of Severe Methemoglobinemia with Shock and High Saturation Gap Following Suicidal Ingestion of Sodium Nitrite-Saved by Oral Methylene Blue
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1 Department of Medicine, Dr. SNMC, Jodhpur - 342003, Rajasthan, IN
1 Department of Medicine, Dr. SNMC, Jodhpur - 342003, Rajasthan, IN
Source
Toxicology International (Formerly Indian Journal of Toxicology), Vol 22, No 3 (2015), Pagination: 147-150Abstract
Here we report a case of sodium nitrite ingestion for suicidal attempt, presented in unconsciousness, shock and deeply cyanosed condition. He was pulseless and had no recordable BP with methemoglobin level of 77% and saturation gap of 20. He was put on ventilator in ICU and treated with ionotropes, oral methylene blue and parental ascorbic acid. He completely recovered after two days with normal methemoglobin level. Survival in a case of methemoglobinemia with extremely high level of methemoglobin, non recordable BP and deep cyanosis is rarely reported. We report this case for awareness about the severity of signs and symptoms depend on the methemoglobin concentration in blood, false results of pulse oximetry and high saturation gap in methemoglobinemia, and about the management of the lethal effect of poisoning.Keywords
Methemoglobinemia, Oral Methylene Blue, Saturation Gap, Shock, Sodium Nitrite.
References
- Hall AH, Kulig KW, Rumack BH. Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Med Toxicol. 1986; 1:253–60.
- Wright RO, Lewander WJ, Woolf AD. Methemoglobinemia: Etiology, pharmacology, and clinical management. Ann Emerg Med. 1999; 34:646–56.
- Mary Denshaw-Burke. Methemoglobinemia. Available from: emedicine.medscape.com/article/204178
- Feiner JR, Bickler PE, Mannheimer PD. Accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia. Anesth Analg. 2010; 111(1):143–8.
- Chongtham DS, Phurailatpam J, Singh MM, Singh TR. Methaemoglobinaemia in nitrobenzene poisoning. J Postgrad Med. 1997; 43:73–4.
- Gowans WJ. Fatal methaemoglobinaemia in a dental nurse. A case of sodium nitrite poisoning. Br J Gen Pract. 1990; 40:470–1.
- Nishiguchi M, Nushida H, Okudaira N, Nishio H. An autopsy case of fatal methemoglobinemia due to ingestion of sodium Nitrite. J Forensic Res. 2015; 6:1.
- Saigal R, Goyal LK, Agrawal A, Wadhwani D, Mittal P, Yadav RN, Meena PD. Methaemoglobinaemia as a result of nitrite poisoning. J Assoc Physicians Ind. 2014; 62:737–8.
- Sohn CH, Seo DW, Ryoo SM, Lee JH, Kim WY, Lim KS, Oh BJ. Life-threatening methemoglobinemia after unintentional ingestion of antifreeze admixtures containing sodium nitrite in the construction sites. Clin Toxicol (Phila). 2014; 52(1):44–7.
- Harvey M, Cave G, Chanwai G. Fatal methaemoglobinaemia induced by self-poisoning with sodium nitrite. Emerg Med Australas. 2010; 22:463–5.
- Centers for Disease Control and Prevention (CDC). Methemoglobinemia following unintentional ingestion of sodium nitrite- New York; 2002. MMWR Morb Mortal Wkly Rep 2002; 51:639–42.
- Kaplan A, Smith C, Promnitz DA, Joffe BI, Seftel HC. Methemoglobinaemia due to accidental sodium nitrite poisoning. Report of 10 cases. S Afr Med J. 1990; 77(6):300–1.
- Saito T, Takeichi S, Yukawa N, Osawa M. Fatal methemoglobinemia caused by liniment solutions containing sodium nitrite. J Forensic Sci. 1996; 41(1):169–71.
- El-Husseini A, Azarov N. Is threshold for treatment of methemoglobinemia the same for all? A case report and literature review. Am J Emerg Med. 2010; 28:748.e10.
- Matteucci O, Diletti G, Prencipe V, Giannatale ED, Marconi MM, Migliorati G. Two cases of methemoglobinaemia caused by suspected sodium nitrite poisoning. Vet Ital. 2008; 44(2):447–53.
- Maric P, Ali SS, Heron LG, Rosenfeld D, Greenwood M. Methaemoglobinaemia following ingestion of a commonly available food additive. Med J Aust. 2008; 188:156–8.
- Jain MD, Nikonova A. Methemoglobinemia from curing salt. CMAJ. 2013; 185(16):771.
- Walley T, Flanagan M. Nitrite-induced methaemoglobinaemia. Postgrad Med J. 1987; 63:643–4.
- Ellis M, Hiss Y, Shenkman L. Fetal methemoglobinemia caused by inadvertent contamination of a laxative solution with sodium nitrite. Isr J Med Sci. 1992; 28(5):289–91.
- Finan A, Keenan P, Donovan FO, Mayne P, Murphy J. Methaemoglobinaemia associated with sodium nitrite in three siblings. BMJ. 1998; 317:1138–9.
- Pahadiya HR, Lakhotia M, Gandhi R, Prajapati GR.The Mysterious Story of brown blood and high Saturation Gap.Indian J Hematol Blood Transfus. 2016;32:517-8.