Toxicology International (Formerly Indian Journal of Toxicology)

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Hematotoxic Effect of Petroleum Fumes on Petrol Filling Attendants and Garage Attendants in South Haryana, India


Affiliations
1 Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Haryana, India
2 Department of Pharmacy, Govt. Polytechnic, Mandi Adampur, Hisar, India
3 Department of Food Technology, Govt. Polytechnic, Mandi Adampur, Hisar, India
     

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The present study was conducted to investigate the impact of occupational exposure of petroleum fumes on hematological profile of petrol filling and garage attendants presently working in our locality i.e. South Haryana, India. A total of 125 adult males (18-40 years) were divided in five groups i.e. control group having grocery shop attendants, petrol filling station attendants with occupational exposure upto and more than 8 years and garage attendants with occupational exposure upto and more than 8 years. Complete blood profile (CBC) was assessed to evaluate the impact of petroleum fumes on hematological profile. A significant fall in red blood cells (RBC), hemoglobin and hematocrit count and significant abnormal rise in mid-sized (MID) cells was observed in all test groups having exposure to petroleum fumes in proportionate to their exposure period. In conclusion, occupational exposure to petroleum fumes may cause anemia and leukemia which worsen with prolonged exposure.

Keywords

Petroleum, Fumes, Attendants, Garage Lead, Benzene, Gasoline.
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  • Hematotoxic Effect of Petroleum Fumes on Petrol Filling Attendants and Garage Attendants in South Haryana, India

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Authors

Kapil Soni
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Haryana, India
Rakesh Kumar Sharma
Department of Pharmacy, Govt. Polytechnic, Mandi Adampur, Hisar, India
Arun Gupta
Pharmacology Division, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Haryana, India
Vedpal Yadav
Department of Food Technology, Govt. Polytechnic, Mandi Adampur, Hisar, India

Abstract


The present study was conducted to investigate the impact of occupational exposure of petroleum fumes on hematological profile of petrol filling and garage attendants presently working in our locality i.e. South Haryana, India. A total of 125 adult males (18-40 years) were divided in five groups i.e. control group having grocery shop attendants, petrol filling station attendants with occupational exposure upto and more than 8 years and garage attendants with occupational exposure upto and more than 8 years. Complete blood profile (CBC) was assessed to evaluate the impact of petroleum fumes on hematological profile. A significant fall in red blood cells (RBC), hemoglobin and hematocrit count and significant abnormal rise in mid-sized (MID) cells was observed in all test groups having exposure to petroleum fumes in proportionate to their exposure period. In conclusion, occupational exposure to petroleum fumes may cause anemia and leukemia which worsen with prolonged exposure.

Keywords


Petroleum, Fumes, Attendants, Garage Lead, Benzene, Gasoline.

References





DOI: https://doi.org/10.22506/ti%2F2017%2Fv24%2Fi1%2F146722