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Gupta, Y. K.
- Synthesis and Physico Chemical Studies of Some Chalcone and Their Derivatives as Potential Antimicrobial Agents
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Authors
Affiliations
1 School of Applied Sciences, Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
1 School of Applied Sciences, Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 4 (2017), Pagination: 1155-1159Abstract
The Chalcone is an aromatic compound that forms the central core for various necessities of biological compounds. The Chalcone is synthesized by Claisen - Schmidt condensation of benzaldehyde derivatives with acetophenone derivatives in dilute ethanolic sodium hydroxide solution at room temperature. The structures of synthesized compounds were investigated by IR Spectroscopy, NMR Spectroscopy and Mass Spectrometry. The antimicrobial activity of the synthesized was evaluated by Filter Paper Disc diffusion Method. The compound 1b showed excellent activity against S. aureus at both concentration i.e. 500μg/ml and1000 μg/ml.Keywords
Chalcone Derivates, Antimicrobial Agents.
- Synthesis, Characterization and Antimicrobial Activities of Some New Amino-Pyrimidine Derivatives
Abstract Views :149 |
PDF Views:0
Authors
Affiliations
1 School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
1 School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 1 (2019), Pagination: 167-171Abstract
In the present work, an efficient synthesis of some new Amino-Pyrimidine Derivatives has been created through response of chalcones of cyclic imides and guanidine nitrate in presence of neutral alumina. The new synthesized amino-pyrimidines showed synergistic significant activities against Candida albicans and Aspergillus nigerfungal strains.Keywords
Amino-pyrimidines, Chalcones, Antimicrobial Activity.References
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