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Rageeb Md. Usman, Md.
- Gastroretentive Drug Delivery System: An Overview
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Authors
Affiliations
1 Ph.D Scholar, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
2 Professor, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
3 Associate Professor, Department of Pharmacognosy, Smt. S.S Patil College of Pharmacy, Chopda (M.S.), IN
1 Ph.D Scholar, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
2 Professor, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
3 Associate Professor, Department of Pharmacognosy, Smt. S.S Patil College of Pharmacy, Chopda (M.S.), IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 3 (2022), Pagination: 1343-1347Abstract
Oral route is considered as the most convenient, accepted and safest way for drug delivery, achieving better therapeutic effectiveness by delivery of drug at specific site in controlled manner is getting more attention now a days and GRDDS is one of the novel approaches which prolongs gastric residence time and releases a drug at specific targeted site of stomach for local or systemic effects. This approach is useful for drugs having narrow absorption window in upper part of GI tract. In this review we have discussed various aspects of GRDDS like merits, demerits, physiology of stomach, and potential drug candidate for GRDDS, factors affecting gastric retention, polymers and other materials used in GRDDS, Various approaches for gastric retention and evaluation of GRDDS concisely.Keywords
GRDDS, Gastro-retention, NDDS, Controlled release, Dosage form.
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- Transdermal Drug Delivery System: An Overview
Abstract Views :83 |
PDF Views:0
Authors
Affiliations
1 Ph.D Scholar, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
2 Professor, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
3 Associate Professor, Department of Pharmacognosy, Smt. S.S Patil College of Pharmacy, Chopda (M.S.)., IN
1 Ph.D Scholar, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
2 Professor, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P)., IN
3 Associate Professor, Department of Pharmacognosy, Smt. S.S Patil College of Pharmacy, Chopda (M.S.)., IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 3 (2022), Pagination: 1371-1377Abstract
From the past three decades there are huge changes and developments in formulation technology. Innovations in drug delivery systems are not only associated with the development of novel dosage forms but also with the development of new formulations using existing drugs for the treatment. These innovations in delivery of drug have many advantages like better patient compliance, maintenance of steady state concentration of drug for the prolong period, reducing dosing frequency, drug targeting to desired site of action and low side effects. TDDS are designed for delivery of drugs across the skin and it provides both controlled and continuous administration drug. It terminates the pulsed entry of drug in systemic circulation due to which side effects are observed. This transdermal route of drug delivery has more benefits and convenience than oral route and enhances the safety and efficacy of drug; it is patient friendly and painless device that provides regulated, uniform administration and the continuous supply of drug to targeted site for treatment of various diseases.Keywords
Transdermal, Drug delivery, Transdermal Patch, Safety, dosage form, Formulation.References
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