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Prabhu, K.
- The GC MS Studies of One Ayurvedic Medicine, Amritarishtam
Abstract Views :140 |
PDF Views:0
Authors
Hassan Mohammad
1,
K. Prabhu
2,
Mudiganti Ram Krishna Rao
3,
R. Lakshmi Sundaram
4,
Sampad Shil
3,
N. Vijayalakshmi
3
Affiliations
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600 092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600 092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 1 (2019), Pagination: 351-356Abstract
The knowledge of the types of biomolecules present in Ayurvedic medicines can help in understanding the underlying mechanism of action of such medicines. This type of study is very pertinent and being sought after in the present day medical scenario, which needs newer and better approaches of treatment. The present study deals with the GC MS analysis of one such Ayurvedic medicine, Amritarishtam, which is used for the treatment of all types of fevers. The medicines was procured from standard Ayurvedic vendor at Chennai and subjected to GC MS analysis after following proper procedures. The GC MS profile indicated the presence of 12 biomolecules, such as, Phenylethyl Alcohol, Ethyl Hydrogen Succinate, 5-Hydroxymethylfurfural, Thymol, Ethanone,1-(2-hydroxy-4-methoxyphenyl)-, Hexadecanoic acid,2-hydroxy-1-(hydroxymethyl)ethyl ester and Ocatadecanoic acid,2,3-dihyroxypropyl ester which have medicinal values relating to that of Amritarishtam. Further work to isolate the molecules and understand their role is in process.Keywords
Ayurveda, Amritarishtam, GC MS, Phenylethyl Alcohol, 6-Hydroxymethylfurfural, Thymol.
References
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- The GC MS Study of one Ayurvedic Medicine, Khadirarishtam
Abstract Views :175 |
PDF Views:0
Authors
Hassan Mohammad
1,
K. Prabhu
2,
Mudiganti Ram Krishna Rao
3,
R. Lakshmi Sundaram
4,
Sampad Shil
3,
N. Vijayalakshmi
3
Affiliations
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 2 (2019), Pagination: 535-540Abstract
The present study of GC MS analysis of one Ayurvedic formulation, Khadirarishtam, was undertaken to know the types of biomolecules present in it. This medicine is used to treat chronic skin ailments. The GC MS profile of Khadirarishtam indicated the presence of some important biomolecules such as Eucalyptol, Phnylethyl alcohol, Ethyl hydrogen succinate, .alpha.-Terpineol, 5-Hydroxymethylfurfural, Acetic acid, chloro-,3-phenylpropyl ester, Eugenol, Benzeethanol,4-hydroxy-, Propanoic acid, anhydride, Benzoic acid, 4-hydroxy-, Disulphide, methyl (methylthio)phenylmethyl, Hexadecnoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester, Octadecanoic acid and 2,3-dihydropropyl ester etc. These biomolecules have been reported to have the medicinal properties which represent those of Khadirarishtam. Further study to establish the molecular mechanism of these compounds is warranted.Keywords
GC MS, Ayurvedic, Khadirarishtam, Eucalyptol, Phnylethyl Alcohol, Ethyl Hydrogen Succinate, Alpha.-Terpineol, 5-Hydroxymethylfurfural.References
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- The GC MS Study of one Ayurvedic Medicine, Vasakadyaristam
Abstract Views :187 |
PDF Views:0
Authors
Muttevi Hyagreva Kumar
1,
K. Prabhu
2,
Mudiganti Ram Krishna Rao
3,
R. Lakshmi Sundaram
4,
Sampad Shil
5,
S. Arun Kumar
5
Affiliations
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
5 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai- 600073, IN
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
5 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai- 600073, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 2 (2019), Pagination: 569-573Abstract
The present study deals with the GC MS analysis of one Ayurvedic prepaation, Vasakadyarishtam, which is a mucolytic medicine used for the treatment of cough, cold, chest congestion asthma and related diseases like bronchitis, inflammation and hemoptysis. The most important constituent of this medicine is Vasaka or Adhatoda vesika plant, which is known for its anti-cough and cold usage in Ayurveda. This study was to understand the main biomolecules present in this medicine by GC MS analysis. The results indicted the presence of some important molecules such as Eucalyptol, Phenylethyl alcohol, Camphor, Ethyl hydrogen succinate, Succinic acid, cyclobutyl ethyl ester, 3-Cyclohexen-1-ol,4-methyl-(1-methylethyl)-(R)-,. alpha.-Terineol, 5- Hydroxymethyl furfural, p-Anisic acid,4-nitrophenyl ester, 2-Propen-1-0l,3-phenyl, Benzeneethanol, 4-hydroxy- Propiophenone, 2‘-(trimethylsioxy)-, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester and Octadecanoic acid and 2,3 –dyhydroxypropyl ester. These molecules are known for their various medicinal properties which indicate their roles in this formulation.Keywords
Vasakadyarishtam, Adhatoda vesika, Eucalyptol, Phenylethyl Alcohol, Camphor, Ethyl Hydrogen Succinate, Alpha.-Terineol.References
- Md. Tofazzal Hossain, Md. Obydul Hoq. Therapeutic use of Adhatoda vasica. Asian J Med Biol Res, 2016; 2 (2): 156-163
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- Dubey D, Patnaik R, Ghosh G, Padhy RN. In Vitro Antibacterial Activity, Gas Chromatography–Mass Spectrometry Analysis of Woodfordia fruticosa Kurz. Leaf Extract and Host Toxicity Testing With In Vitro Cultured Lymphocytes from Human Umbilical Cord Blood. Osong Public Health and Research Perspectives, 2014; 5(5): 298-312.
- Grover N, Patni V. Phytochemical characterization using various solvent extracts and GC MS analysis of methanolic extract of Woodfordia fruticosa (L.) KURZ. Leaves. Int J Pharm Pharm Sci, 2013; 5(4): 291-295.
- Verma SK, Jain V, Katewa SS. Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum). Indian Journal of Biochemistry and Biophysics, 2009; 46(6): 503-506.
- Khan A, Khan QJ, Gilani A. Pharmacological basis for the medicinal use of cardamom in asthma. Bangladesh J Pharmacol, 2011; 6: 34-37.
- Ranasinghe P, Pigera S, Sirimal GA, Galappaththy PP, Constantine GR, Prasad K. Medicinal properties of ‗true‘cinnamon (Cinnamomum zeylanicum): a systematic review. BMC Complementary and Alternative Medicine, 2013; 13: 275.
- Jayaprakasha GK, Rao LJ. Chemistry, biogenesis, and biological activities of Cinnamomum zeylanicum. Crit Rev Food Sci Nutr, 2011; 51: 547–562.
- Lima ZP, Severi JA, Pellizzon CH, Brito AR, Solis PN. Gastroprotective activity of Cinnamomum tamala leaves on experimental gastric ulcers in rats, J. Ethnopharmacol. 2010; 128: 537-40.
- Hemayet H, Howlader MSI, Dey SK, Hira A. Evaluation of antiinflammatory activity of Cinnamomum tamala (Buch.-Ham.) Leaves growing in Bangladesh, Int. J Pharmachol., 2012; 1(2):114-21.
- Jamiuddin A, Sultana N, Dewan SMR, Amin MN, Uddin SMN. Determination of Chemical Groups and Investigation of Anthelmintic, Cytotoxic, and Antibacterial Activities of Leaves of Cinnamomum tamala (Family: Lauraceae), Int J Pharmamedix Ind., 2013; 1(2): 222-32
- Ankurdeep Preety, Sandeep Sharma. A Brief Review on Cinnamomum tamala (Buch.-Ham.) Nees & Eberm.: An Important Medicinal Tree. International Journal of Research in Biological Sciences, 2016; 6(2): 26-31
- Chahar K, Kumar SDS, Geetha L, Lokesh T, Manohara KP. Mesua ferrea L.: A review of the medical evidence for its phytochemistry and pharmacological actions. African Journal of Pharmacy and Pharmacology, 2013; 7(6): 211-219.
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- The GC MS Study of one Ayurvedic Medicine, Aragwadharishtam
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Authors
Hassan Mohammad
1,
K. Prabhu
2,
Mudiganti Ram Krishna Rao
3,
R. Lakshmi Sundaram
4,
Sampad Shil
3,
N. Vijayalakshmi
3,
Sruthi Dinakar
5
Affiliations
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600 092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
5 Ayurvedic Practitioner, Kottakkal Arya Vaidya Sala, Chennai, IN
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, IN
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600 092, IN
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, IN
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, IN
5 Ayurvedic Practitioner, Kottakkal Arya Vaidya Sala, Chennai, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 3 (2019), Pagination: 1111-1114Abstract
Aragwadharishtam is an Ayurvedic preparation used mainly to detoxify the body. Its main use is in the cure of skin diseases, ulcers and piles. The present study deals with the GC MS analysis of Aragwadharishtam to know the presence of phytochemicals present in this medicine. The GC MS profile indicated the presence of some very important molecules such as Phnylethyl alcohol, Ethyl hydrogen succinate, Butanedioic acid diethyl ester, 4-Ethyl-2-hydroxycyclopent-2-en-1-one, Eugenol, Ethyl gallate, 1,2,3- Benzenetriol, Benzeethanol,4-hydroxy-, Hexadecanoic acid, 2-hydroxy -1-(hydroxymethyl) ethyl ester and Octadecanoic acid, 2,3-hydroxypropyl ester etc. These molecules have a number of important medicinal roles which could substantiate their participation towards the medicinal activity of Aragwadharishtam as a detoxifying formula as claimed by Ayurveda. However, further work in this direction is warranted to prove the medicinal efficacy of the medicine.Keywords
Aragwdharishtam, Ayurvedic, GC MS, Phnylethyl Alcohol, Ethyl Hydrogen Succinate, Butanedioic Acid Diethyl Ester, 4-Ethyl-2-Hydroxycyclopent-2-en-1-One, Eugenol.References
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