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Musfiroh, Ida
- Differentiation Roselle (Hibiscus Sabdariffa L.) Extract from Various Plants with FTIR-chemometric Method
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1 Department of Pharmaceutical Biology, Faculty of Pharmacy, Padjadjaran University, Jalan Raya Bandung- Sumedang KM 21, Jatinangor, West Java,, ID
2 Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Padjadjaran University, Jalan Raya Bandung- Sumedang KM 21, Jatinangor, West Java,, ID
1 Department of Pharmaceutical Biology, Faculty of Pharmacy, Padjadjaran University, Jalan Raya Bandung- Sumedang KM 21, Jatinangor, West Java,, ID
2 Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Padjadjaran University, Jalan Raya Bandung- Sumedang KM 21, Jatinangor, West Java,, ID
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Research Journal of Pharmacy and Technology, Vol 15, No 2 (2022), Pagination: 878-884Abstract
Background: Roselle prospectively can be developed as herbal medicine raw materials. The high amount availability of roselle raw material sources leads to diverse roselle extract quality therefore a particular method is required to differentiate roselle extracts. FTIR-chemometric is a method that is used to evaluate plant quality by processing chemical data information through mathematically and statistically calculations. Aim: The purpose of this study is to obtain data differentiation from all of the roselle extract obtained from various regions, identify from which region roselle extract has similar group with roselle standard extract, and identify the relation between roselle extracts quality with soil examination parameter. Materials and Method: Roselle simplisia collections were obtained from 12 regions which were Parangtritis, Nganjuk, Kediri, Ponorogo, Blitar, Bogor, Tulungagung, Boyolali, Yogyakarta, Sukabumi, Cileunyi, dan Malang. The extraction method used was using maceration with 70% ethanol. FTIR-chemometric was utilized to analyze. Results: Based on the results showed that FTIR-chemometric method can be used to differentiate roselle extract from several locations, roselle extract obtained from Tulungagung, Boyolali, and Sukabumi were in similar group with roselle extract standard, and roselle extract obtained from Tulungagung, Boyolali, and Sukabumi had similar soil examination parameter which were Phosphorus and Magnesium.Keywords
Roselle, FTIR-chemometric, Soil parameter.References
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- Effect of Pelvic Floor Muscle Training with Biofeedback on Stress Urinary Incontinence in Females, Kelantan, Malaysia: A Pilot Study
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Authors
Affiliations
1 Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran., IN
2 Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, IN
3 Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran., IN
4 Faculty Of Pharmacy, Universitas Halu Oleo, Kendari, Southeast Sulawesi, ID
5 Departemen of Pharmacy, Faculty of Science and Technology, Mandala Waluya Kendari High School of Health Science, Southeast Sulawesi, ID
6 Departement of Medical Laboratory Technology, Mandala Waluya Kendari High School of Health Science, Southeast Sulawesi, ID
1 Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran., IN
2 Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, IN
3 Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran., IN
4 Faculty Of Pharmacy, Universitas Halu Oleo, Kendari, Southeast Sulawesi, ID
5 Departemen of Pharmacy, Faculty of Science and Technology, Mandala Waluya Kendari High School of Health Science, Southeast Sulawesi, ID
6 Departement of Medical Laboratory Technology, Mandala Waluya Kendari High School of Health Science, Southeast Sulawesi, ID
Source
Research Journal of Pharmacy and Technology, Vol 15, No 4 (2022), Pagination: 1837-1842Abstract
Introduction: Lawsonia inermis L is a medicinal herb from Lythraceae family. This plant is proven to be able to treat various diseases. Lawsonia inermis L is one of the flowering plant of a single species of the genus Lawsonia. This plant contains the main active compounds such as flavonoids, phenols, alkaloids, glycosides, saponins, tannins, and essential oils. Flavonoids and phenols are the active compounds which most commonly found. Objective : This study aims to determine the quality parameters of the extract which include specific and non-specific parameters, antioxidant activity and total flavonoid content in purified extracts of Lawsonia inermis L. Methodology: The extract was obtained by maceration method using 96% ethanol. Purified extract was obtained by separating the chlorophyll and tannins contained in the sample using ethanol and aqudes, then continued by partitioning using ethyl acetate and adding MgSO4 as a drying agent. The ethyl acetate phase was concentrated using a Rotary Vacuum Evaporator to obtain a purified extract with a reddish black color. Furthermore, the extract was analyzed using thin layer chromatography (TLC) using eluent n-hexane: ethyl acetate (1: 1). Result : Specific parameters include organoleptic observations, water-soluble compounds and ethanol-soluble compounds, while non-specific parameters include drying loss, moisture content, total ash content, acid soluble content, specific gravity, microbial contamination, mold/yeast contamination, Pb metal contamination, Cd and As. The antioxidant activity assay used the DPPH method and the IC50 value was 39.07 mg / L, while the total flavonoid test used quercetin as a comparison and the total flavonoid content was 3.29%. Conclusion : The purified extract of Lawsonia inermis L. leaves comply the quality standard of the extract, has very strong antioxidant activity and contains flavonoids.Keywords
Lawsonia inermis L, Standardization, Radical DPPH, Total Flavonoids.References
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