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Hussain, Hutham Abd Ali Abd Al
- Synthesis and Characterization New Heterocyclic Compounds Derivatives from Vanillin
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1 Department of Physiology and Pharmacology/College of Veterinary Medicine/University of Kerbala, IQ
2 Department of Chemistry, College of Sciences/University of Kerbala, IQ
1 Department of Physiology and Pharmacology/College of Veterinary Medicine/University of Kerbala, IQ
2 Department of Chemistry, College of Sciences/University of Kerbala, IQ
Source
Research Journal of Pharmacy and Technology, Vol 12, No 4 (2019), Pagination: 1943-1946Abstract
In this article, some new heterocyclic derivatives, for example pyrimidine and pyrazoles were synthesized by reaction vanillin with paracetamol utilizing KOH as a catalyst to synthase 3-(4-hydroxy-3-methoxyphenyl)-N-(4- hydroxyphenyl)acrylamide(1).The compound (1) on react with Sodium azide, hydrazine, urea, and thiourea in the existence of acetic acid or KOH and ethanol as a catalyst to give (2,3,4,5) compounds. The reaction monitors by TLC. All synthesized compounds have been distinguished by melting point, IR, 1H.NMR spectroscopy.Keywords
Vanillin, Paracetamol, Heterocyclic.References
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