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Martadila Putri, Hernalia
- Oral-genital Lichenoid Reaction: A Rare Hypersensitives to Drug, a Review
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Authors
Nanda Rachmad Putra Gofur
1,
Aisyah Rachmadani Putri Gofur
2,
Rizki Nur Rachman Putra Gofur
3,
Mega Kahdina
3,
Hernalia Martadila Putri
4,
Soesilaningtyas
5
Affiliations
1 Department of Health, Faculty of Vocational Studies, Universitas Airlangga,, ID
2 Narizma Healthcare, Surabaya, ID
3 HVA Hospital, Pare Kediri, East Java., ID
4 Narizma Healthcare, Surabaya,, ID
5 Deptartment of Dental Nursing, Politeknik Kesehatan Kementrian Kesehatan, ID
1 Department of Health, Faculty of Vocational Studies, Universitas Airlangga,, ID
2 Narizma Healthcare, Surabaya, ID
3 HVA Hospital, Pare Kediri, East Java., ID
4 Narizma Healthcare, Surabaya,, ID
5 Deptartment of Dental Nursing, Politeknik Kesehatan Kementrian Kesehatan, ID
Source
Research Journal of Pharmacy and Technology, Vol 15, No 2 (2022), Pagination: 903-907Abstract
Background: Lichenoid reaction as the result of hypersensitivity from drug might be had similir clinical appearance to idiopathic lichen planus. Lichenoid drug reaction is termed as a condition of the oral cavity having an identifiable etiology, which is clinically and histologically similar to oral lichen planus and also manifest on genital. A number of drugs have been described as a causative factor of those reactive lesions. Objectives : The aim of this study is to finding mechanism of oral-genital lichenoid reaction caused by drugs. Problem Statement: Potential Pathway of Oral-genital lichenoid reaction caused by drugs. Discussion: Oral lichenoid lesions could be impact from medication and contact antigenic reaction. Clinical condition these two look similar to oral lichen planus, also its pathology. Studies of LDR caused by angiotensin-converting enzyme (ACE) inhibitors, antimalaria, antituberculosis, antitumor and non-steroidal anti-inflammatory drugs (NSAIDs) have been found. Conclusion: OLR is a disease condition with definite identifiable aetiology. Cell-mediated immune dysregulation has been associated with pathogenesis, explaining oral and genital manifestation.Keywords
Lichenoid Reaction, Oral-genital, Drug, Hypersensitives.
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