Research Journal of Pharmacy and Technology

P. Ranadheer Chowdary ¹, D. Praveen ¹, M. Vijey Aanandhi ²

Affiliations
1 Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, IN
2 Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, IN

Abstract

Background: Diabetes Mellitus is a metabolic syndrome characterized by increased blood sugar levels in the body. Dyslipidemia in diabetes is one of the most important reasons for silent heart attacks. The main aim and Objectives of this study are to evaluate the incidence of dyslipidemia after the diagnosis of Diabetes mellitus

Methodology: A prospective non interventional single centred study was carried out in a tertiary care hospital. A specially designed proforma was used to collect the data from the case sheets such as patient demographics. Lipid profile values were obtained from the patient after obtaining written consent from each patient and correlated with American Dyslipidemic Associations standard values. The incidence rate was calculated.

Results: We have included 500 patients in this study. We also observed that there were isolated, combined and mixed patterns of dyslipidemia in Diabetes Mellitus. The incidence rate was found to be 45.60%. Although there was no significant difference between the incidence rate of men and women.

Conclusion: Dyslipidemia in Diabetes Mellitus possess a major threat of myocardial risk and heart attacks. As HbA₁C is monitored every 3 months we recommend the monitoring of lipid profile test also every 3 months. Regular monitoring of Lipid Profile is an important way to prevent silent heart attacks.

Keywords

Incidence, Dyslipidemia, Diabetes Mellitus.

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D. Pavithra ¹, D. Praveen ², M. Vijey Aanandhi ³

Affiliations
1 Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University, Chennai, IN
2 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University, Chennai, IN
3 Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, IN

Abstract

The misuse of drugs which are taken through intravenously have been a cause in youngsters which would lead to major health disorders that could increase the morbidity and mortality rate to an higher ratio following complications, infections and permanent health disorders. The introduction of mind-altering substances into body through intravenous needle reports to addiction which is a source for unending complications causing higher death rates. Certain drugs are injected into muscles, under skin or directly into the vein, where tack marks can be seen which would be a sign for chronic intravenous drug use. Collapsed vein is the common effect due to intravenous drug use. Cocaine, heroin, crystal methamphetamine, amphetamines, opiates and prescription drugs are used among IV users. Prescription drugs are taken via injection illegally including barbiturates to hydrocodone, consuming them for certain reason other than for what they are prescribed for and with altered dose along with altered route of administration. Due to rapid onset of action the addicts prefer intravenous method for induction of drugs into their body. Major complications could be faced by IV drug abusers which includes severe blood-borne diseases, infections, abscesses, collapsed veins, increased chance of over dose since intravenous administration has rapid onset of action which bypasses body's detoxifying system. patient Counselling remains as best treatment to addicts which would help them to get rid of the habit followed by the infectious disease that are due to misuse of drug could be treated with appropriate antibiotics along with antiviral drugs depending on the type of infection they have undergone. A comprehensive literature search has been carried out in PubMed, Google Scholar, and articles pertaining to complications of intravenous drug use were selected for review.

Keywords

Drug Abuse, Intravenous, Complications.

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