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Authors
Affiliations
1 School of Applied Sciences, Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
Source
Research Journal of Pharmacy and Technology, Vol 10, No 4 (2017), Pagination: 1155-1159
Abstract
The Chalcone is an aromatic compound that forms the central core for various necessities of biological compounds. The Chalcone is synthesized by Claisen - Schmidt condensation of benzaldehyde derivatives with acetophenone derivatives in dilute ethanolic sodium hydroxide solution at room temperature. The structures of synthesized compounds were investigated by IR Spectroscopy, NMR Spectroscopy and Mass Spectrometry. The antimicrobial activity of the synthesized was evaluated by Filter Paper Disc diffusion Method. The compound 1b showed excellent activity against S. aureus at both concentration i.e. 500μg/ml and1000 μg/ml.
Keywords
Chalcone Derivates, Antimicrobial Agents.
