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Microfluidics Design by using Soft Lithographic Techniques and Their Applications


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1 Amity University Rajasthan, Jaipur-303002, India
 

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The current work described the background of various kinds of lithographic techniques, their properties, advantages, disadvantages, and applications. In this work, we have conducted experimental studies on various kinds of polymers. With the help of these polymers, we have designed micron level channel for the free flow of any kind of liquids, named as micron channel for microfluidics. It may be broadly called as microfluidics design. Also, we have worked for the optimization of the fabricated channel using various polymers. This kind of microfluidics design will be used for various aspects in biomedical engineering applications such as targeted drug delivery, ready to use medical handy kits etc. We are now in the way to design microfluidics channel for a fast and rapid sensor for detection of septic etc.

Keywords

Lithography, Microfluidics, Polymers.
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  • Ho, C. M. B., Ng, S. H., Li, K. H. H., & Yoon, Y. J., “3D printed microfluidics for biological applications,” Lab on a Chip, 15(18), 2015, pp 3627-3637.

  • Weaver, Peter., “ The Technique of Lithography,” London: B.T. Batsford, 1964, p. 49.

  • Rus, D., & Tolley, M. T., “Design, fabrication, and control of soft robots,” Nature, 521(7553),2015, p 467.

  • Meggs, Philip B., “ A History of Graphic Design,”John Wiley & Sons, Inc., 1998, p. 146.

  • Yazdi, A. A., Popma, A., Wong, W., Nguyen, T., Pan, Y., & Xu, J., “ 3D printing: an emerging tool for novel microfluidics and lab-on-a-chip applications,” Microfluidics and Nanofluidics, 20(3), 2016, p. 50.

  • Carter, Rob, Ben Day, Philip Meggs, Typographic Design: Form and Communication, Third Edition, John Wiley & Sons, Inc., 2002, p. 11.

  • Faustino, V., Catarino, S. O., Lima, R., & Minas, G., “Biomedical microfluidic devices by using low-cost fabrication techniques: A review,” Journal of Biomechanics, 49(11), 2016, pp. 2280-2292.

  • A. B. Hoen, Discussion of the Requisite Qualities of Lithographic Limestone, with Report on Tests of the Lithographic Stone of Mitchell County, Iowa,” Iowa Geological Survey Annual Report, 1902, Des Moines, 1903; pp. 339–352.

  • Au, A. K., Huynh, W., Horowitz, L. F., & Folch, A., “ 3D printed microfluidics,” Angewandte Chemie International Edition, 55(12), 2016, pp. 3862-3881.

  • Pennel ER, ed., “Lithography and Lithographers, ” London: T. Fisher Unwin, 1915.

  • Chan, H. N., Chen, Y., Shu, Y., Chen, Y., Tian, Q., & Wu, H., “ Direct, one-step molding of 3D-printed structures for convenient fabrication of truly 3D PDMS microfluidic chips,” Microfluidics and Nanofluidics, 19(1), 2015, pp. 9-18.

  • Hannavy, John., “ Encyclopedia of nineteenth-century photography: A-I, index,” Volume 1. Taylor & Francis, ISBN 9780415972352, 2008, p. 865.

  • Xia, Y., Si, J., & Li, Z., “Fabrication techniques for microfluidic paper-based analytical devices and their applications for biological testing: A review,” Biosensors and Bioelectronics, 77, 2016, pp. 774-789.

  • Mansuripur, Masud, “ Classical Optics and Its Applications,” Cambridge University Press, ISBN 9780521804998, 2002, p. 416.

  • Bhattacharjee, N., Urrios, A., Kang, S., & Folch, A., “ The upcoming 3D-printing revolution in microfluidics,” Lab on a Chip, 16(10), 2016, pp.1720-1742.

  • Faulkner, A. & Shu, W., "Biological cell printing technologies, " Nanotechnology Perceptions. 8,2012, pp. 35–57.

  • Warkiani, M. E., Khoo, B. L., Wu, L., Tay, A. K. P., Bhagat, A. A. S., Han, J., & Lim, C. T., “Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics,” Nature Protocols, 11(1), 2016, pp.134-148.

  • M. Singh et al., "Inkjet Printing - Process and Its Applications," Advanced Materials, 2009.

  • Kamei, Ken-ichiro et al. ,"3D printing of soft lithography mold for rapid production of polydimethylsiloxane-based microfluidic devices for cell stimulation with concentration gradients," Biomedical Microdevices 17.2, 2015, p. 36.

  • Karl S. Forester, "Lexmark International, Inc. v. Static Control Components, Inc.: Findings of Fact and Conclusions of Law", 2003.

  • Garrett White, "Nash Editions: Fine Art Printing on the Digital Frontier," Digitaljournalist.org. Retrieved 2011-10-20.

  • Luong, Q.-Tuan, “An overview of large format color digital printing,” at largeformatphotography.info

  • Advertising printing manufacturer, MFG Advertising, 4 May 2013.

  • Sudhanshu Singh, Yuvraj Vidyadhar, “PDMS based air pollution detection sensor using microfluidics technology,” ICBA Special Issue 5 (12), 2016, pp. 16-19.

  • Sudhanshu Singh, Sangeeta Shekhawat, “ Microfluidics-based air pollutants detection device by using solvent cast method,” ICBA Special Issue 5 (12), 2016, pp. 20-23.

  • Mark, J. E., Allcock, H. R., West, R. “Inorganic Polymers,” Prentice Hall, Englewood, NJ: 1992. ISBN 0-13-465881-7

  • Lotters, J. C., Olthuis, W., Veltink, P. H., Bergveld, P., "The mechanical properties of the rubber elastic polymer polydimethylsiloxane for sensor applications". J Micromech Microeng. 7 (3),1997, pp. 145–147.

  • McDonald, J. C., Duffy, D. C., Anderson, J. R., Chiu, D. T., Wu, H., Schueller, O. J. A., Whitesides, G. M., "Fabrication of microfluidic systems in poly(dimethylsiloxane)," Electrophoresis, 21 (1), 2000, pp. 27–40.

  • H. Hillborg, J.F. Ankner, U.W. Gedde, G.D. Smith; H.K. Yasuda; K. Wikstrom, "Crosslinked polydimethylsiloxane exposed to oxygen plasma studied by neutron reflectometry and other surface specific techniques," Polymer. 41 (18), 2000, pp. 6851–6863.

  • Lee, J. N., Park, C., Whitesides, G. M. "Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices, " Anal. Chem. 75 (23), 2003, pp. 6544–6554.

  • Jesse Greener, Wei Li, Judy Ren, Dan Voicu, Viktoriya Pakharenko, Tian Tang and Eugenia Kumacheva, "Rapid, cost-efficient fabrication of microfluidic reactors in thermoplastic polymers by combining photolithography and hot embossing, " Lab Chip, 2010.

  • Nemani, Krishnamurthy V., Moodie, Karen L., Brennick, Jeoffry B., Su, Alison, Gimi, Barjor, "In vitro and in vivo evaluation of SU-8 biocompatibility," Materials Science and Engineering: C. 33 (7), 2013, pp. 4453–4459.

  • S. Arscott "SU-8 as a material for lab-on-a-chip-based mass spectrometry, "Lab on a Chip, 14(19),2014, pp.3668-3689.


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  • Microfluidics Design by using Soft Lithographic Techniques and Their Applications

Abstract Views: 126  |  PDF Views: 86

Authors

Sudhanshu Singh
Amity University Rajasthan, Jaipur-303002, India
Vandna Singh
Amity University Rajasthan, Jaipur-303002, India

Abstract


The current work described the background of various kinds of lithographic techniques, their properties, advantages, disadvantages, and applications. In this work, we have conducted experimental studies on various kinds of polymers. With the help of these polymers, we have designed micron level channel for the free flow of any kind of liquids, named as micron channel for microfluidics. It may be broadly called as microfluidics design. Also, we have worked for the optimization of the fabricated channel using various polymers. This kind of microfluidics design will be used for various aspects in biomedical engineering applications such as targeted drug delivery, ready to use medical handy kits etc. We are now in the way to design microfluidics channel for a fast and rapid sensor for detection of septic etc.

Keywords


Lithography, Microfluidics, Polymers.

References