Medico-Legal Update

Hussam Abbas Dawood ¹, Farah A. Al-Marzook ², Rabab Omran ³

Affiliations
1 PhD Lecturer, Adult Nursing Department, College of Nursing, University of Babylon, IQ
2 PhD Lecturer, College of Nursing, University of Warith Al-anbiya’a, IQ
3 PhD Prof. Department of Biology, College of Science, University of Babylon, IQ

Abstract

Oxidative stresses are affected in an inequality among the creation of reactive oxygen species (ROS) and a biological system’s capability to voluntarily purify responsive intermediates or simply healing the causing destruction. Catalase was an antioxidant enzyme that acting a most important role in monitoring hydrogen peroxide focus at human cells. H₂O₂ is dissolved in H₂O and O₂ by CAT, Protecting the oxidative stress cells. It has proposed which helpful polymorphism moves the enzyme action within the gene coding catalase enzyme, thereby reducing safety against oxidative stress. Between February and October 2018 a total of thirty-five patients and fifteen control subjects were gathered. The genotyping of catalase were achieved consuming polymerase chain reaction (PCR) in addition to restriction fragment length polymorphism (RFLP). We tend to determine no significant difference within the genotype frequencies of catalase among patients with hypertension and controls using the P = 0.06, OR = 7.36 (0.77-69.5)).

Keywords

Hypertension, RFLP, Catalase , SNPs. Polymorphisms.

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Abdulridha Mohammed Al-Asady ¹, Farah A. Al-marzook ², Thoalffakar A. ALhamed ¹

Affiliations
1 Assist.Lecturer, College of Nursing, University of Warith Al-anbiya’a, IQ
2 Lecturer, College of Nursing, University of Warith Al-anbiya’a, IQ

Abstract

Diabetes Mellitus (DM) is a collection of metabolic diseases categorized by hyperglycemia caused by insulin excretion deficiencies, insulin performance, or both DM are categorized into distinct kinds. Type 1 diabetes (T1D) is defined by breakdown of β-cells, generally resulting in complete insulin deficiency. Type 2 diabetes (T2D) is a consequence of peripheral tissue insulin resistance. a complete of fifty patients and fifty control subjects were collected between February to October 2018. The genotyping of catalase were attained consuming polymerase chain reaction (PCR) in addition to restriction fragment length polymorphism (RFLP). We tend to firm vigorous changes within the genotype occurrences of catalase between patients with diabetes and controls using the P=0.038, OR =0.58 (0.48-0.78).

Keywords

Diabetes, RFLP, catalase, SNPs. Polymorphisms

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