Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Primary Non-Hodgkin’s Lymphoma of the Mandible in an Immunocompetent Patient


Affiliations
1 Department of Oral Medicine, Diagnosis and Radiology, SGRD Institute of Dental Sciences and Research, Amritsar, Punjab, India
2 Department of Prosthodontics and Crown and Bridge and Implantology, SGRD Institute of Dental Sciences and Research, Amritsar, Punjab, India
3 Department of Oral Medicine and Radiology, Government Dental College and Hospital, Mumbai, Maharashtra, India
4 Department of Pathology, GMC, Amritsar – 143001, Punjab, India
     

   Subscribe/Renew Journal


Non-Hodgkin’s Lymphoma (NHL) is very commonly associated with immunosuppressive states. Its occurrence in an immunocompetent person is scarcely reported in literature. Although NHL is known to occur in the jaws, mandibular involvement with invasion in bone is an uncommon entity. Dental surgeons should be aware that NHL can present in the oral cavity as a non-tender swelling or ulceration and should be included in the differential diagnosis of oral swellings and ulcers. Histopathological examination, assessment of immune status of the patient and search for primary or metastatic lesions should be a part of the diagnostic work up. A case of NHL of the mandible in an immunocompetent patient with follow up is presented here.


Keywords

Immunocompromised State, Lymphoma, Malignant Lesions of the Jaw, Mandibular Bone Invasion, Non- Hodgkin’s Lymphoma.
User
Subscription Login to verify subscription
Notifications
Font Size

  • Reddy I, Sreenath G, Reddy YR, Prakash AR, Swathi TR. Non-Hodgkin’s lymphoma in buccal vestibule-case report. J Clin Diagn Res. 2014; 8(8):QD01202.
  • Inchingolo F, Tatullo M, Abenavoli FM et al. NonHodgkin lymphoma affecting the tongue: Unusual intra-oral location. Head Neck Oncol. 2011; 3(1):1–5. https://doi.org/10.1186/1758-3284-3-1. PMid:21205320.
  • PMCid:PMC3022892
  • Varun R, Varghese NO, Sivakumar TT, Joseph AP. Extranodal non-hodgkin’s lymphoma of the oral cavity: A case report. Iran J Med Sci. 2017; 42(4):407–11.
  • Nittayananta W, Chungpanich S, Pongpanich S, Mitarnun W. AIDS-related non-Hodgkin’s lymphoma presenting as delayed healing of an extraction wound. Br Dent J. 1996; 181:102–4. https://doi.org/10.1038/sj.bdj.4809172. PMid:8810110
  • Kini R, Saha A, Naik V. Diffuse large B-cell lymphoma of mandible: A case report. Med Oral Patol Oral Cir Bucal. 2009; 14:e421–24.
  • Parrington SJ, Punnia-Moorthy A. Primary non-Hodgkin’s lymphoma of the mandible presenting following tooth extraction. BDJ. 1999; 187:468–70. https://doi.org/10.1038/sj.bdj.4800308. PMid:10729980
  • Longo F, De Maria G, Esposito P, Califano L. Primary nonHodgkin’s lymphoma of the mandible: report of a case. Int J Oral Maxillofac Surg. 2004; 33:801–3. https://doi.org/10.1016/j.ijom.2003.12.003. PMid:15556331
  • Van der Waal RI, Huijgens PC, Van der Valk P, van der Waal I. Characteristics of 40 primary extranodal nonHodgkin lymphomas of the oral cavity in perspective of the new WHO classification and the International Prognostic Index. Int J Oral Maxillofac Surg. 2005; 34:391–5. https://doi.org/10.1016/j.ijom.2004.08.009.
  • PMid:16053848
  • Bhatt VR, Koirala B, Terjanian T. Extranodal natural killer/T cell lymphoma, nasal type presenting as a palatal perforation and naso-oral fistula. BMJ Case Rep. 2011. https://doi.org/10.1136/bcr.11.2010.3511. PMid:22707606. PMCid:PMC3063295
  • Toliusis, Pamerneckas A, Petrulis A, Tamulaitis G, Pilipavicius G, Pijadin A. Primary non-Hodgkin’s lymphoma of bone. Medicina (Kaunas). 2004; 40(4):379–85.

Abstract Views: 177

PDF Views: 0




  • Primary Non-Hodgkin’s Lymphoma of the Mandible in an Immunocompetent Patient

Abstract Views: 177  |  PDF Views: 0

Authors

Preeti Chawla Arora
Department of Oral Medicine, Diagnosis and Radiology, SGRD Institute of Dental Sciences and Research, Amritsar, Punjab, India
Aman Arora
Department of Prosthodontics and Crown and Bridge and Implantology, SGRD Institute of Dental Sciences and Research, Amritsar, Punjab, India
Easwaran Ramaswami
Department of Oral Medicine and Radiology, Government Dental College and Hospital, Mumbai, Maharashtra, India
Saurabh Arora
Department of Pathology, GMC, Amritsar – 143001, Punjab, India

Abstract


Non-Hodgkin’s Lymphoma (NHL) is very commonly associated with immunosuppressive states. Its occurrence in an immunocompetent person is scarcely reported in literature. Although NHL is known to occur in the jaws, mandibular involvement with invasion in bone is an uncommon entity. Dental surgeons should be aware that NHL can present in the oral cavity as a non-tender swelling or ulceration and should be included in the differential diagnosis of oral swellings and ulcers. Histopathological examination, assessment of immune status of the patient and search for primary or metastatic lesions should be a part of the diagnostic work up. A case of NHL of the mandible in an immunocompetent patient with follow up is presented here.


Keywords


Immunocompromised State, Lymphoma, Malignant Lesions of the Jaw, Mandibular Bone Invasion, Non- Hodgkin’s Lymphoma.

References





DOI: https://doi.org/10.18311/%2Fjpfa%2F2020%2F25584