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Dhote, Swati
- Studies on Antigenotoxic Effect of Piper betle Leaves
Abstract Views :367 |
PDF Views:323
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Journal of Natural Remedies, Vol 7, No 2 (2007), Pagination: 247-251Abstract
Objective: To study the antigenotoxic effect of Piper betle leaves in Gamma irradiation and Cyclophosphamide treated animals. Materials and methods: Swiss albino mice were given 50% methanolic extract (100mg/kg body weight.) of Piper betle leaves and antigenotoxic effect was studied after whole body gamma irradiation (4Gy) & cyclophosphamide (50mg/kg body weight.) treatment. Bone marrow protection was studied by scoring aberration in metaphase chromosomes. Results: No drug toxicity was observed at given dose (100mg/kg body weight.) Methanol extract ½ hr prior to irradiation protects animals against Gamma irradiation & Cyclophosphamide treatment.Keywords
Anti-genotoxic Activity, Piper betle, Gamma Irradiation, CyclophosphamideFull Text
- Studies on Anti-genotoxic Effect of Piper betle Leaves
Abstract Views :411 |
PDF Views:362
Authors
Source
Journal of Natural Remedies, Vol 7, No 2 (2007), Pagination: 247-251Abstract
Objective: To study the antigenotoxic effect of Piper betle leaves in Gamma irradiation and Cyclophosphamide treated animals. Materials and methods: Swiss albino mice were given 50% methanolic extract (100mg/kg body weight.) of Piper betle leaves and antigenotoxic effect was studied after whole body gamma irradiation (4Gy) & cyclophosphamide (50mg/kg body weight.) treatment. Bone marrow protection was studied by scoring aberration in metaphase chromosomes. Results: No drug toxicity was observed at given dose (100mg/kg body weight.) Methanol extract ½ hr prior to irradiation protects animals against Gamma irradiation & Cyclophosphamide treatment.Keywords
Anti-genotoxic Activity, Piper betle, Gamma Irradiation, CyclophosphamideFull Text