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Nowadays plants are the traditional product that has little or no side effects in modern medicine. The Thunbergia fragrans belong to the family Acanthaceae which contains more biologically active phytoconstituents. The plant leaves were extracted with different solvents including ethanol, aqueous, hexane and ethyl acetate. These extracts have been subjected to phytochemical study. The results of the qualitative phytochemical analysis indicate that the ethanol extracts provided more phytoconstituents. The phytochemical quantitative analysis showed that the ethanol had a higher amount of flavonoid. The ethanol extract of Thunbergia fragrans contained antioxidant and antibacterial activity. The GCMS study for the compound identification was studi

Keywords

Antioxidant, Antimicrobial, Ethanolic Extract, GCMS, Thunbergia fragrans

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References

Pan SY, Litscher G, Gao SH, Zhou SF, Yu ZL, Chen HQ, et al. Historical perspective of traditional indigenous medi- cal practices: the current renaissance and conservation of herbal resources. Evid Based Complement Alternat Med. 2014; 2014:1–20. https://doi.org/10.1155/2014/525340. PMid:25610481 PMCid:PMC4295149

PayamalleS, Shinde S, Joseph KS, Mutakekar S, Murgude M, Tawadare R, Murthy HN. Chemical properties and fatty acid composition of Thunbergia fragrans Roxb. Seed Oil. J Am Oil Chem Soc. 2015; 93(2):295–7. https://doi. org/10.1007/s11746-015-2767-4

Uddin MJ, Alam MN, Biswas K, Rahman MA. In vitro antioxi- dative and cholinesterase inhibitory properties of Thunbergia grandiflora leaf extract. Cogent Food Agric. 2016; 2(1):1–11. https://doi.org/10.1080/23311932.2016.1256929

Zhao S, Baik OD, Choi YJ, Kim SM. Pretreatments for the Efficient extraction of bioactive compounds from plant-based biomaterials. Crit Rev Food Sci Nutr. 2014; 54(10):1283–97. https://doi.org/10.1080/10408398.2011.632698. PMid:24564586

Nagarasan S, Boominathan M. Perspective pharmacologi- cal activities of Leucas aspera: An indigenous plant species. Indo Am J Pharm. 2016; 6(09):6567–72.

Magel E. Qualitative and quantitative determination of starch by a colorimetric method. Starch-Stärke. 1991; 43(10):384–7. https://doi.org/10.1002/star.19910431003

Fang W, Wu Y, Zhou J, Chen W, Fang Q. Qualitative and quantitative determination of taxol and related compounds in TaxuscuspidataSieb et Zucc. Phytochem Anal. 1993; 4(3):115–19. https://doi.org/10.1002/pca.2800040307

Nagarasan S, Boominathan M. Invitro studies on the primitive pharmacological activities of Adhatoda vasica. Int J Life Sci. 2016; 4(3):379–85.

Gomathi D, Kalaiselvi M, Ravikumar G, Devaki K, Uma C.

GC-MS analysis of bioactive compounds from the whole plant ethanolic extract of Evolvulus alsinoides (L.) L. J Food Sci. Technol. 2013; 52(2):1212–17. https://doi.org/10.1007/ s13197-013-1105-9. PMid:25694742. PMCid:PMC4325072

Sethuraman J, Nehru H, Shanmugam K, Balakrishnanan P. Evaluation of potent phytochemicals and antidiabetic activity of Ficus racemosa L. World J Pharm Res. 2017; 6(15):909–20.

Balakrishnan P, Kumar GS, Ramalingam PS, Nagarasan S, Murugasan V, Shanmugam K. Distinctive pharmacological activities of Eclipta alba and it’s coumestan wedolactone. Indo Am J Pharm. 2018; 5(4): 2996-3002. https://doi. org/10.5281/zenodo.1231062.

Filip S, Vidović S, Vladić S, Pavlić B, Adamović D, Zeković Z. Chemical composition and antioxidant properties of Ocimum basilicum L. extracts obtained by supercritical carbon dioxide extraction: Drug exhausting method. J Supercrit Fluids. 2016; 109:20–5. https://doi.org/10.1016/j.supflu.2015.11.006

Ramalingam PS, Sagayaraj M, Ravichandiran P, Balakrishnanan P, Nagarasan S, Shanmugam K. Lipid peroxidation and anti-obesity activity of Nigella sativa seeds. World J Pharm Res. 2017; 6(10):882–92. https://doi. org/10.20959/wjpr201710-9389

Aruna AP, Balakrishnan P, Shanmugam K, Rajendran K. Biological finger printing of microbial diversity in vermi- compost of different raw materials. Indo Am J Pharm. 2017; 7(04):8497–8501.

Balakrishnan P, Musafargani TA, Subrahmanyam S, Shanmugam K. A perspective on bioactive compounds from Solanum trilobatum. J Chem Pharm. 2015; 7(8):507– 12.

Soni V, Jha AK, Dwivedi J, Soni P. Qualitative and quan- titative determination of phytoconstituents in some antifertility herbs. Indian J Pharm Sci. 2018; 80(1):79–84. https://doi.org/10.4172/pharmaceutical-sciences.1000332

Purushothaman B, Srinivasan RP, Suganthi P, Ranganathan B, Gimbun J, Shanmugam KA. Comprehensive Review on Ocimum basilicum. J Nat Remedies. 2018; 8(3):41–55. https://doi.org/10.18311/jnr/2018/21324

Shanmugam K, Purushothaman B, Suganthi N. Qualitative and quantitative determination of various extracts of Ocimum basilicum L. leaves. J Nat Remedies. 2020; 20(1):53–60. https://doi.org/10.18311/jnr/2020/24113

Marotti M, Piccaglia, R, Giovanelli E. Differences in essen- tial oil composition of Basil (Ocimum basilicum L.) Italian cultivars related to morphological characteristics. J Agric Food Chem. 1996; 44(12):3926–29. https://doi.org/10.1021/ jf9601067

Sundaramoorthy M, Prabaharan C, Balakrishnan P, Saravanan TS. Antibacterial and wound healing effects of semi-purified heart proteins from certain selective slaugh- ter house animals. Indo Am J Pharm. 2014; 4(01).

Rathnasamy S, Rufus AL, Purusothaman. Comparative studies on isolation and characterization of allinase from garlic and onion using Pegylation- A novel method. Asian J Chem. 2014; 26(12):3733–5. https://doi.org/10.14233/ ajchem.2014.17064

Mahdi-Pour B, Jothy SL, Latha LY, Chen Y, Sasidharan S. Antioxidant activity of methanol extracts of different parts of Lantana camara. Asian Pacific Journal of Tropical Biomedicine. 2012; 2(12):960-965. https://doi.org/10.1016/ S2221-1691(13)60007-6

Chan E, Tie P, Soh E, Law Y. Antioxidant and antibacte- rial properties of green, black, and herbal teas of Camellia sinensis. Pharmacogn. Res. 2011; 3(4):266. https://doi. org/10.4103/0974-8490.89748. PMid:22224051. PMCid: PMC3249787

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