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Vasuki, R.
- Studies on Anti-diarrhoeal Activity of Citrus sinensis Peel Extract
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Journal of Natural Remedies, Vol 9, No 1 (2009), Pagination: 51-55Abstract
The methanolic extract of the Citrus sinensis peel was screened for antidiarrhoeal activity using animal models against castor oil induced diarrhoea. The parameters evaluated are small intestine secretion by enteropooling assay, rate of defecation and small intestine transit. The methanolic extract showed significant activity (p<0.05) against castor oil induced diarrhoea and interluminal accumulation of fluid. It also reduced gastrointestinal motility after charcoal meal administration in albino mice. The results indicates that the action of Citrus sinensis peel extract (CSPE) could be through a combination of inhibition of elevated prostaglandin biosynthesis and reduced propulsive movement of the small intestine.Keywords
Citrus Sinensis, Anti Diarrhoeal, Albino Mice, Castor Oil and Charcoal Meal- Invitro and Invivo Anti-Arthritic Activity of Combined Ethanolic Extracts of Calotropis gigantea and Cardiospermum halicacabum in Wistar Rats
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