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Patil, M. B.
- Wound Healing Activity of the Galls of Quercus infectoria Olivier
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Journal of Natural Remedies, Vol 2, No 1 (2002), Pagination: 54-58Abstract
Objective: To screen the wound healing activity of different extracts of galls of Quercus infectoria on incision, excision and dead space (granulation) wound models in albino rats. Materials and method: Crude aqueous extract of Quercus infectoria galls and its three different crude fractions, petroleum ether (40°-60°C), solvent ether, ethyl acetate were tested for various preliminary phytoconstituents and were screened at dose of 100mg/kg for wound healing properties in incision, excision and dead space (granulation) wound models in albino rats. Results: Tannins, flavonoids, steroids and carbohydrates were found to be present in aqueous extract and its various fractions of galls of Quercus infectoria. In resutured incision wound models aqueous extract and its fractions showed significant (P<0.01) breaking strength compared to control. In excision wound parameters the aqueous extract promotes better wound healing (96.36%) compared to control and organic fractions. Breaking strength of the grass pith induced granuloma studies the results show significant (P<0.01) activity in case of aqueous extract along with solvent ether fraction. Conclusion: From the results obtained, it can be observed that aqueous extract and its fractions of galls of Quercus infectoria have significant wound healing property. Also it can be concluded that flavonoids may be responsible for wound healing activity.Keywords
Quercus infectoria, Wound-healing, Aqueous Extract, Soxhlet Extraction- Effect of Lawsonia alba Leaf Extracts on Carbon tetrachloride-induced Hepatic Damage in Albino Rats
Abstract Views :474 |
PDF Views:407
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Journal of Natural Remedies, Vol 3, No 1 (2003), Pagination: 97-100Abstract
Objectives: To screen the hepatoprotective activity of leaves of Lawsonia alba against carbon tetrachloride induced hepatotoxicity in albino rats. Method: Studies on the hepatoprotective activity of the leaves of Lawsonia alba were carried out in albino rats. The Lawsonia alba leaf ethanolic extract and three different fractions obtained from it were screened for hepatoprotective activity using carbon tetrachloride-induced hepatic damage model in rats. Doses for the different fractions and ethanolic extract were selected based on the results of acute toxicity studies in mice. The effect was assessed by serum enzyme profile, viz., glutamic oxaloacetate transaminase (GOT) and glutamic pyruvate transaminase (GPT) levels, and histopathological changes in liver. Results: Lawsonia alba ethanolic extract significantly protected from biochemical and histological changes induced by carbontetrachloride in rats. Conclusion: Ethanolic extract of Lawsonia alba leaves exhibited a significant protection against carbon tetrachloride-induced hepatic damage in rats.Keywords
Carbon Tetrachloride, Hepatoprotective Activity, Leaves of Lawsonia alba Lam. (Lythraceae), Liv.52 Syrup, Olive Oil, 5% Gum Acacia, SGPOT, SGPT- Anti-diabetic Activity of Holarrhena antidysenterica (Linn.) Wall, Bark on Alloxan Induced Diabetic Rats
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PDF Views:528