Refine your search
Collections
Co-Authors
Journals
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Vihashinee, E.
- Antibacterial and in vitro Anticancer Study of Methanol Extracts of Clitoria ternatea Leaves
Abstract Views :316 |
PDF Views:405
Authors
Arunava Das
1,
G. Shanmuga Priya
1,
S. Soundariya
1,
P. Deepesh
1,
Aileen Rose Edwin
1,
E. Vihashinee
1,
A. Rubiga
1,
S. Megavarthini
1,
R. Eswaran
1,
J. Bindhu
1
Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, IN
Source
Journal of Natural Remedies, Vol 20, No 2 (2020), Pagination: 96-102Abstract
Clitoria ternatea is often known as butterfly pea plant by the natives and is one of the major plants used in Ayurveda and traditional medicine worldwide. It is also used in food and cosmetic industries for various purposes. In this study, methanol leaf extract of Clitoria ternatea was studied for its antibacterial and in vitro anticancer study against human promyelocytic leukemia cells (HL60). Secondary metabolites like alkaloids, phlobatannin, triterpenoids, flavonoids, lipids, steroids, terpenoids, tannins and glycosides are identified in the extract by phytochemical screening. Leaf extract showed the presence of ethers and carboxylic acid groups (GCMS analysis). The leaf extract showed resistance against Salmonella typhi. Thus, from this study it can be concluded Clitoria ternatea leaves methanol extract has bioactive compounds showing anticancer activity against HL60 cells.Keywords
Antibacterial Activity, Anticancer Activity, Clitoria ternatea, GC-MS Analysis, Phytochemical Screening, MTT Assay.References
- Balaji KS, Priyanka S, Preethi SD, Chandrashekara KT, Lokesh S. Angio-suppressive effect of Clitoria ternatea flower extracts is mediated by HIF-1α and down-regulation of VEGF in Murine carcinoma model. Medicinal Chemistry (Los Angeles). 2016; 6:515–20. https://doi.org/10.4172/2161-0444.1000392
- Chakraborthy GS, Kumar V, Gupta S, Kumar A, Gautam N, Kumari L. Phytochemical and pharmacological aspects of Clitoria ternatea-a review. Journal of Applied Pharmaceutical Sciences and Research. 2018:3–9. https://doi.org/10.31069/apsr.v1i2.13061
- Deepika S, Selvaraj I, Anbalagan M. Phytochemical characterization and cancer cell line cytotoxicity of Clitoria ternatea. Bangladesh Journal of Pharmacology. 2018; 13(4):349–52. https://doi.org/10.3329/bjp.v13i4.38612
- Divya A, Anbumalarmathi J, Sharmili SA. Phytochemical analysis, antimicrobial and antioxidant activity of Clitoria ternatea blue and white flowered leaves. Advances in Research. 2018:1–13. https://doi.org/10.9734/AIR/2018/39030
- Lakshmi NDM, Mahitha B, Madhavi T, Sushma NJ. Phytochemical screening and ftir analysis of Clitoria ternatea leaves. International Journal of Scientific and Engineering Research. 2015; 6(2):287–90.
- Jacob L, Latha MS. Anticancer activity of Clitoria ternatea Linn. against Dalton’s lymphoma. International Journal of Pharmacognosy and Phytochemical Research. 2012; 4(4):207–12.
- Jamil N, Zairi MNM, Nasim NAIM, Pa’ee F. Influences of environmental conditions to phytoconstituents in Clitoria ternatea (Butterfly Pea Flower)-A Review. Journal of Science and Technology. 2018; 10(2).
- Kamilla L, Mansor SM, Ramanathan S, Sasidharan S. Effects of Clitoria ternatea leaf extract on growth and morphogenesis of Aspergillus niger. Microscopy and Microanalysis. 2009; 15(4):366–72. https://doi.org/10.1017/S1431927609090783. PMid:19575837
- Kumar D, Dhobi M. Antianxiety and antioxidant profile of blue and white variety of Clitoria ternatea L. Indian Journal of Research in Pharmacy and Biotechnology. 2016; 4(3):90.
- Lijon MB, Meghla NS, Jahedi E, Rahman MA, Hossain I. Phytochemistry and pharmacological activities of Clitoria ternatea. International Journal of Natural and Social Sciences. 2017; 4(1):1–10.
- Mathew N, Anitha MG, Bala TSL, Sivakumar SM, Narmadha R, Kalyanasundaram M. Larvicidal activity of Saracaindica, Nyctanthesarbor-tristis, and Clitoria ternatea extracts against three mosquito vector species. Parasitology Research. 2009; 104(5):1017–25. https://doi.org/10.1007/s00436-008-1284-x. PMid:19039604
- Nguyen KNT, Nguyen GKT, Nguyen PQT, Ang KH, Dedon PC, Tam JP. Immunostimulating and Gram‐negative‐specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea). The FEBS Journal. 2016; 283(11):2067–90. https://doi.org/10.1111/febs.13720. PMid:27007913
- Pasukamonset P, Kwon O, Adisakwattana S. Alginatebased encapsulation of polyphenols from Clitoria ternatea petal flower extract enhances stability and biological activity under simulated gastrointestinal conditions. Food Hydrocolloids. 2016; 61:772–9. https://doi.org/10.1016/j.foodhyd.2016.06.039
- Kumar TR, Kumar S, Anju VS. Phytochemical and antibacterial activities of crude leaf and ischolar_main extracts of Clitoria ternatea varieties (Fabaceae). Journal of Pharmacognosy and Phytochemistry. 2017; 6(6):1104–8.
- Sarumathy K, Rajan MD, Vijay T, Jayakanthi J. Evaluation of phytoconstituents, nephro-protective and antioxidant activities of Clitoria ternatea. Journal of Applied Pharmaceutical Science. 2011; 1(5):164–72.
- Antimicrobial, Antioxidant and Anticancer Activity of the Ethanol Extract of Pleurotus ostreatus
Abstract Views :286 |
PDF Views:248
Authors
J. Bindhu
1,
Arunava Das
1,
E. Vihashinee
1,
A. Rubiga
1,
Aswin Edward
1,
R. Eswaran
1,
G. Shanmuga Priya
1,
S. Soundariya
1,
Aileen Rose Edwin
1
Affiliations
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
1 Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode District, Tamil Nadu, IN
Source
Journal of Natural Remedies, Vol 20, No 2 (2020), Pagination: 110-115Abstract
The current study evaluates antimicrobial, antioxidant and anticancer activity of the ethanol extract of Pleurotus ostreatus. Chemical analysis showed the presence of alcohol, amides, alkanes, ether, phenol and sulphides. Most of the chemical constituents were found to be esters and carboxylic acid derivatives. The extract showed highest resistant against Bacillus cereus. P. ostreatus ethanol extract showed comparable antioxidant activity with ascorbic acid in both DPPH and FRAP method and also showed an IC50 of 39.29 μg/ml against HL60 cells.Keywords
MTT, DPPH, HL-60 Cells, FRAP, GC-MS.References
- Prasad AS, Bao B, Beck FWJ, Kucuk O, Sarkar FH. Antioxidant effect of zinc in humans. Free Radical Biology Medicine. 2004; 37:1182–90. https://doi.org/10.1016/j.freeradbiomed.2004.07.007 PMid:15451058
- Jose N, Ajith TA, Janardhanan KK. Antioxidant, anti-inflammatory and antitumor activities of culinary-medicinal mushroom Pleurotus pufmonanus (Fr.) Quel. (Agaricomycetideae). International Journal of Medicinal Mushrooms. 2002; 4:329–35. https://doi.org/10.1615/IntJMedMushr.v4.i4.60
- Jayakumar T, Ramesh E, Geraldine P. Antioxidant activity of the oyster mushroom Pleurotus ostreatus on CCl4-induced liver injury in rats. Food and chemical toxicology. 2016; 44:1989–96. https://doi.org/10.1016/j.fct.2006.06.025.PMid:16914248
- Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer, Chemical Biological Interaction. 2006; 160:1–40. https://doi.org/10.1016/j.cbi.2005.12.009. PMid:16430879
- Woldegiorgis AZ, Abate D, Haki GD, Ziegler GR. Antioxidant property of edible mushrooms collected from Ethiopia. Food Chemistry. 2014; 157:30–6. https://doi.org/10.1016/j.foodchem.2014.02.014. PMid:24679748
- Michalak A. Phenolic compounds and their antioxidant activity in plants growing under heavy metal stress. Polish Journal of Environmental Studies. 2006; 15:523–30.
- Oyetayo VO, Ariyo OO. Antimicrobial and antioxidant properties of Pleurotus ostreatus (Jacq: Fries) cultivated on different tropical woody substrates. Journal of Waste Conversion, Bioproducts and Biotechnology. 2013; 2:28–32.
- Oboh G, Ademosun AO. Characterization of the antioxidant properties of phenolic extracts from some citrus peels. Journal of Food Science and Technology. 2012; 49:729–36. https://doi.org/10.1007/s13197-010-0222-y. PMid:24293692 PMCid:PMC3550823
- Vishwakarma P, Singh P, Tripathi NN. In-vitro antioxidant activity and nutritional value of four wild oyster mushroom collected from North-Eastern Part of Uttar Pradesh. Mycosphere. 2017; 8:592–602. https://doi.org/10.5943/mycosphere/8/4/8
- Singh V, Pandey R, Vyas D. Antioxidant potentiality of Pleurotus ostreatus (MTCC142) cultivated on different agro wastes. Asian Journal of Plant Science and Research. 2015; 5:22-7.
- Riaz M, Mehmood KT. Selenium in human health and disease. Journal of Postgraduate Medicine. 2012; 26:120–33.