Refine your search
Collections
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Saraswathy, A.
- Toxicity Studies on Amukkarac Curanam - a Siddha Poly Herbal Drug
Abstract Views :406 |
PDF Views:484
Authors
Source
Journal of Natural Remedies, Vol 8, No 2 (2008), Pagination: 232-241Abstract
Objective: The effect of Amukkarac curanam (AC), a widely used Siddha medicine was evaluated for acute and chronic toxicity in rats. Material and methods: Amukkarac is botanically equated to Withania somnifera Dunal. Acute dosages were 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 and 5.0 g/kg body weight while the chronic dosage was 500 mg/kg body weight /day. All external morphological, hematological, serum parameters, histopathological, in addition to body weight and vital organ weights were recorded. Results and conclusion: During this investigation no significant mortality was observed. The results showed that AC at the given dose of 500 mg/kg body weight did not produce any significant toxic effect in rats during 90 days period of the treatment.Keywords
Chronic Toxicity, Hematology, Marker Enzymes, Lipid Profile- Control of Urinary Risk Factors of Stones by Padina boergesenii (Allander and Kraft), a Brown Algae in Experimental hyperoxaluria
Abstract Views :472 |
PDF Views:412
Authors
Source
Journal of Natural Remedies, Vol 3, No 2 (2003), Pagination: 189-194Abstract
Objective: In view of the continued screening of seaweeds of the Gulf of Mannar for biological activity Padina boergesenii, the most common species along the Mandapam coast was identified to study the various biological effects. Padina spp, exhibits diuretic effect hence, the antiurolithiatic effect of Padina boergesenii was tested in hyperoxaluric male albino rats. Methodology: Urolithiasis was induced in rats by feeding 3% glycolic acid along with pyridoxine deficient diet. The effect of the seaweed extract (ethanolic) at different doses was determined by comparing with the controls. Results: The ethanolic extract of Padina boergesenii at a dose of (150 & 200mg /kg p.o) significantly reduced the calcium excretion to normal level and significantly decreased oxalate excretion, thus reducing the risk of calcium oxalate super-saturation in urine as compared to the pyridoxine deficient control rats. The extracts also slightly elevated phosphorous, decreased uric acid and raised the magnesium excretion. Protein and creatinine elimination was effectively normalized by the extracts. Conclusion: The antiurolithiatic activity exhibited by the ethanolic extract is related to the chemical constituents in the algae which is discussed.Keywords
Padina boergesenii, Brown Algae, Urolithiatic Activity, Pyridoxine, Magnesium- Hepatoprotective Effect of Amukkarac curanam in Acetaminophen Intoxicated Rats
Abstract Views :580 |
PDF Views:372