Journal of Academy of Dental Education

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Aquaporins in Salivary Gland-The Water Fa(u)cet of an Acini?


Affiliations
1 Penang International Dental College, NH-47, Sankari Main Road, Veerapandi Post, Salem – 636308, Tamil Nadu, India
2 Vinayaka Mission's Sankarachariyar Dental College, NH-47, Sankari Main Road, Ariyanoor, Salem – 636308, Tamil Nadu, India
 

Salivary glands are exocrine glands secreting saliva into the oral cavity. The primary function of the saliva is to protect and hydrate the mucosal structures of the oral cavity. The lubrication and hydration of the oral mucosa is provided by the water content of the saliva which forms approximately 99% of its composition. Aquaporins are water channels expressed in acini of salivary glands and play an important role in formation of saliva. Aquaporins are transmembrane water permeable proteins involved in transcellular water flow. In addition to being permeable to water, some Aquaporins can be permeable to small solutes, including cations, glycerol and gases. The present article reviews the basic histology of salivary gland, its ductal system and also physiology of secretion of saliva and highlights the role of Aquaporins in saliva formation.

Keywords

Aquaporins, Clinical Application, Expression, Localization, Salivary Gland, Structure.
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  • Aquaporins in Salivary Gland-The Water Fa(u)cet of an Acini?

Abstract Views: 361  |  PDF Views: 131

Authors

Elvie Lim Chien Hui
Penang International Dental College, NH-47, Sankari Main Road, Veerapandi Post, Salem – 636308, Tamil Nadu, India
Faith Chuah Ci Kim
Penang International Dental College, NH-47, Sankari Main Road, Veerapandi Post, Salem – 636308, Tamil Nadu, India
Nur Khamalin Nalisa Binti Kamaruddin
Penang International Dental College, NH-47, Sankari Main Road, Veerapandi Post, Salem – 636308, Tamil Nadu, India
A. Thentamil
Penang International Dental College, NH-47, Sankari Main Road, Veerapandi Post, Salem – 636308, Tamil Nadu, India
Mathew Jacob
Vinayaka Mission's Sankarachariyar Dental College, NH-47, Sankari Main Road, Ariyanoor, Salem – 636308, Tamil Nadu, India

Abstract


Salivary glands are exocrine glands secreting saliva into the oral cavity. The primary function of the saliva is to protect and hydrate the mucosal structures of the oral cavity. The lubrication and hydration of the oral mucosa is provided by the water content of the saliva which forms approximately 99% of its composition. Aquaporins are water channels expressed in acini of salivary glands and play an important role in formation of saliva. Aquaporins are transmembrane water permeable proteins involved in transcellular water flow. In addition to being permeable to water, some Aquaporins can be permeable to small solutes, including cations, glycerol and gases. The present article reviews the basic histology of salivary gland, its ductal system and also physiology of secretion of saliva and highlights the role of Aquaporins in saliva formation.

Keywords


Aquaporins, Clinical Application, Expression, Localization, Salivary Gland, Structure.

References





DOI: https://doi.org/10.18311/jade%2F2018%2F21450