International Journal of Physiology

Nandini Agarwal ¹, V K Deshpande , D A Biswas ², Rashmi Babbar ³

Affiliations
1 Senior Resident,Department of Physiology, Maulana Azad Medical College, New Delhi
2 Head of Department of Physiology, Jawaharlal Nehru Medical College, Sawangi, Wardha
3 Head of Department, Department of Physiology, Maulana Azad Medical College, New Delhi

Abstract

Background: Diabetes mellitus is metabolic disorder of multiple etiologies characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects of insulin secretion, insulin action or both. The study was conducted with an aim to evaluate the effect of type II Diabetes mellitus on auditory brainstem response and conduction velocity of median nerve(motor component) and sural nerve (sensory component) and to correlate between auditory neuropathy and peripheral neuropathy due to type II Diabetes mellitus. The present study was undertaken in the Neurophysiology Laboratory, Department of Physiology, Jawaharlal Nehru Medical College Sawangi(Meghe) Wardha. It was a cross sectional case control study and a total of 100 subjects were studied out of which 50 were diabetics and 50 were age and sex matched controls. Effective nerve stimulation was obtained by the stimulus duration of 50μs to 1000μs and 0-100mA. Supramaximal stimulation (10-30% more than the current)was given. Electrode impedence was kept below 5k. BAEPs were recorded with the help of a computerized evoked potential recording system by monoaural stimulation and all the parameters have been compared at 70dBnHL stimulus intensityThe duration of diabetes in the study group with mean+S.D. is 6.92+2.08 years. There was no statistical significant difference in mean age and gender between the control group andstudygroup We founded increase in latency of waveV and interpeak latency III-V. There was decreased conduction velocity in median nerve and sural nerve of upper limb and lower limbfor motor nerve and sensory nerve respectively

Keywords

Diabetes Mellitus, Brainstem Auditory Evoked Potential, Nerve Conduction Velocity

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