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Jaitly, A. K.
- Antihyperglycaemic Activity of Six Edible Plants in Validated Animal Models of Diabetes Mellitus
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Authors
Affiliations
1 Deptt. of Plant Sciences, M.J.P. Rohilkhand Univ., Bareilly, IN
2 Central Drug Research Institute, Lucknow-226001, IN
1 Deptt. of Plant Sciences, M.J.P. Rohilkhand Univ., Bareilly, IN
2 Central Drug Research Institute, Lucknow-226001, IN
Source
Indian Journal of Science and Technology, Vol 2, No 4 (2009), Pagination: 80-86Abstract
The fruits of edible hypoglycaemic plants of Momordica charantia, dried seeds of Syzigium cumini, seed oil of Aegle marmelos and dried fruit powder of Coccinia indica, dried powder of the ischolar_mains and rhizomes of Curcuma longa and seeds of Trigonella foenumgraecum were tested on normoglycaemic as well as streptozotocin-induced diabetic rats for its antihyperglycaemic efficacy. The investigation confirms the traditional claim of antihyperglycaemic activity in these edible plants.Keywords
Antihyperglycaemic Activity, Momordica Charantia, Coccinia Indica, Syzigium Cumini, Aegle Marmelos, Curcuma Longa, Trigonella Foenum-graecumFull Text
References
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- An Approach to overcome Imbalance Datasets of Eukaryotic Genomes during the Analysis by Machine Learning Technique (SVM)
Abstract Views :413 |
PDF Views:99
Authors
Affiliations
1 Department of Plant Sciences, MJP Rohilkhand University Bareilly (U.P), IN
2 Bioinformatics Centre, IVRI, Izatnagar, Bareilly-243122 (U.P), IN
1 Department of Plant Sciences, MJP Rohilkhand University Bareilly (U.P), IN
2 Bioinformatics Centre, IVRI, Izatnagar, Bareilly-243122 (U.P), IN
Source
Indian Journal of Science and Technology, Vol 4, No 5 (2011), Pagination: 520-524Abstract
In biology, Support Vector Machines (SVM) is most frequently used tool for the analysis of gene expression, microarray experiments and other biological applications. In human genome dataset, only a small proportion of the DNA sequences represent genes, and the rest do not. In our work, we highlighted the reasons why, particular SVM, fails and what can be done to overcome this.Keywords
Imbalanced Dataset, BioSVMFull Text
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- Target Binding Hotspot Secrets of mir1 microRNA in Oryza sativa by using Bioinformatics Approaches
Abstract Views :395 |
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Authors
Affiliations
1 Department of Plant Science, M. J. P. Rohilkhand University, Bareilly, IN
2 Bioinformatics Centre, IVRI, Izatnagar, Bareilly, IN
3 Department of Biotechnology, Ministry of Science and Technology, New Delhi, IN
1 Department of Plant Science, M. J. P. Rohilkhand University, Bareilly, IN
2 Bioinformatics Centre, IVRI, Izatnagar, Bareilly, IN
3 Department of Biotechnology, Ministry of Science and Technology, New Delhi, IN
Source
Indian Journal of Science and Technology, Vol 6, No 8 (2013), Pagination: 5058-5064Abstract
Thermodynamic properties and nucleic acid symmetry of upstream nucleotide regions to the binding sites, insertion sites or upstream to the gene regions in the eukaryotic genomes are very significant in revealing the properties of various elements such as microRNA sequence, gene sequence and Promoter sequence etc. They set signals for various microRNA to bind at specific location in the genomes and these sequences also help in gene regulation with microRNA. The miR-1 microRNA is one of the most important and common type of small microRNA precursor that regulates its target protein's expression in the cell of both plants and animals therefore its study is very significant. The main emphasis of this research and whole idea behind this kind of work is to find out upstream sequences which carry hidden properties like Railway signals and track sign board which can alert the drivers that how the way is ahead. MicroRNAs are of approximately 21-nucleotides long and play very significant role in gene regulation in variety of genes of different organisms. MicroRNAs and mRNAs (messenger RNA) constitute an important part of gene regulatory networks, influencing diverse biological phenomena. The mRNA (messengerRNA) translated in to protein by the process of translation but when microRNA binds to specific mRNA sequence it alters the gene regulation process this results the alteration in the resulting protein and its function. The binding mechanism of microRNA at target site is not very clear so the study in this field may reveal some secrets which can be helpful to understand the process of binding of microRNA at different mRNA for regulation in different genes. The analysis of upstream nucleotide sequences to the possible binding sites of microRNA in Oryza sativa untranslated mRNA sequences revealed some significant patterns or signals such as thermodynamic properties signals, sequence architectural signals, and energy consideration which may involve directly or indirectly for the binding of microRNA in Oryza sativa.Keywords
PremicroRNA, RicemicroRNAFull Text
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