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Shouche, Yogesh
- Indian Human Microbiome Initiative:Indian-Ness through the Magnifying Glass
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1 National Centre for Cell Science, Ganeshkhind, Pune 411 007, IN
1 National Centre for Cell Science, Ganeshkhind, Pune 411 007, IN
Source
Current Science, Vol 112, No 02 (2017), Pagination: 207-208Abstract
The quest for the molecular basis of genetic inheritance began with Griffith's experiments in 1928, and by 1944 it was unequivocally established that DNA is the molecule which carries the genetic information. The initial techniques for DNA sequencing developed by Maxam, Gilbert and Sanger were revolutionary and yielded useful information.- Drug Discovery:Mining Microbes for Bioactive Compounds
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PDF Views:138
Authors
Affiliations
1 National Environmental Engineering Research Institute, CSIR, Nehru Marg, Nagpur 440 020, IN
2 National Centre for Microbial Resource, Pune 411 021, IN
3 Omni Active Health Technologies, Mumbai 400 013, IN
1 National Environmental Engineering Research Institute, CSIR, Nehru Marg, Nagpur 440 020, IN
2 National Centre for Microbial Resource, Pune 411 021, IN
3 Omni Active Health Technologies, Mumbai 400 013, IN
Source
Current Science, Vol 113, No 12 (2017), Pagination: 2234-2236Abstract
A collaborative programme involving industry and academia was initiated in September 2007 by the Department of Biotechnology to screen the bacterial diversity from various ecological niches in the country to search for novel bioactive molecules for therapeutic applications. The programme was designed to collect resource samples from the less-explored ecological niches at regular intervals for three years, to ensure a steady supply of microbes for high-throughput screening (HTS). The project had two major components. The first was targeted to generate a repository of 250,000 bacteria in three years by the academic research groups. The other component was preparation of microbial extracts and their screening on HTS platforms in four therapeutic areas followed by chemical profiling of potent extracts. Figure 1 shows the overall project plan.References
- Sharma, A. and Shouche, Y., Indian J. Microbiol., 2014, 54, 129–133.
- Rossello-Moraa, R. and Amann, R., Syst. Appl. Microbiol., 2015, 38, 209–216.
- Cuellar, M. C. and van der Wielen, L. A., Curr. Opin. Biotechnol., 2015, 33, 39–45.
- Harvey, A. L., Edrada-Ebel, R. and Quinn, R. J., Nature Rev. Drug Discovery, 2015, 14, 111–129.
- Forner, D., Berrue, F., Correa, H., Duncan, K. and Kerr, R. G., Anal. Chim. Acta, 2013, 805, 70–79.
- Gaudencio, S. P. and Pereira, F., Nat. Prod. Rep., 2015, 32, 779–810.
- Is Biological Diversity Act Hampering Biodiversity Research?
Abstract Views :563 |
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Authors
Affiliations
1 National Centre for Cell Science, Pune 411 007, IN
1 National Centre for Cell Science, Pune 411 007, IN
Source
Current Science, Vol 117, No 12 (2019), Pagination: 1931-1932Abstract
The Biological Diversity Act 2002 was enacted to meet the obligations of the Convention on Biological Diversity (CBD) and ensure fair and equitable sharing of benefits arising from India’s rich biodiversity. This was followed by the establishment of the National Biodiversity Authority (NBA) which regulates the access of biological resources in the country. The act and the rules that followed were found to be too restrictive by many and even the Department of Biotechnology and the Ministry of AYUSH, Government of India (GoI) have raised several objections to them. The matter was further complicated by the way some provisions are being interpreted by the administering Ministry, i.e. the Ministry of Environment, Forest and Climate Change (MoEFCC), GoI, and the lack of coordination that resulted in different states making their own rules which in some cases are contradictory to the central act.- Sad Status of Microbial Taxonomy Research in India
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Authors
Affiliations
1 National Centre for Cell Science, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune 411 007, IN
1 National Centre for Cell Science, NCCS Complex, University of Pune Campus, Ganeshkhind, Pune 411 007, IN
Source
Current Science, Vol 119, No 6 (2020), Pagination: 887-888Abstract
No Abstract.Keywords
No Keywords.- Anjali Shiras (1962–2020)
Abstract Views :323 |
PDF Views:120
Authors
Affiliations
1 National Centre for Cell Science, Pune 411 007, IN
1 National Centre for Cell Science, Pune 411 007, IN