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V. Velmurugan ¹, I. Bharathithasan ¹, A. Nirmala Grace ¹

Affiliations
1 Centre for Nanotechnology Research, VIT University, Vellore, IN

Abstract

Nanofluids are nanoscale colloidal suspensions containing condensed nanomaterials. Nanofluids have been found to possess enhanced thermos-physical properties such as thermal conductivity, thermal diffusivity, viscosity, and convective heat transfer coefficients compared to those of base fluids like oil or water. Boron Nitride (BN) nanoparticles - due to its high thermal conductivity, appropriate thermal expansion coefficient, high electrical insulation and high mechanical strength is a promising additive in traditional heat exchange fluids. In this work we synthesised Boron Nitride (BN) nanoparticles by hydrothermal method and the nanoparticles are characterized by XRD, EDAX and SEM. Nanofluids were prepared by different weight fractions of the nanoparticles in different ratio of water and Ethylene Glycol (EG) solution. Physiothermal properties of the fluids at different temperatures were investigated and the same is reported.

Keywords

Boron Nitride, Nanofluid, Nanoparticles, Thermal conductivity, Viscosity.

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V. Velmurugan ¹, T. Sundarrajan ¹, A. Chandran ², G. Arunachalam ²

Affiliations
1 Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, IN
2 PGP College of Pharmaceutical Science and Research Institute, Namakkal, Tamilnadu, IN

Abstract

In this work we studied the diuretic potential of aqueous and ethanolic leaves extract of Cardiospermum halicacabum Linn in experimental Wister rats. The ethanolic extract was done by Continuous Hot Percolation method and the aqueous extract was done by Maceration method. Both aqueous and ethanolic Extract of Cardiospermum halicacabum Linn was tested to check the presence of different active constituents like alkaloids, flavonoids, glycosides, terpenoids and saponins. The aqueous and ethanolic leaves extract Cardiospermum halicacabum Linn was used for diuretic activity at the dose 200 mg/kg was compared with standard drug furosemide (10 mg/kg). Various ion concentrations like Sodium, Potassium, Chloride and urine volume was measured. Urine volume increases in aqueous extract than the ethanolic extract. Both the extract showed more urine volume when compared to control but less than that of standard drug. The significant increases in Sodium, Potassium and Chloride ion concentration in both the extract group.

Keywords

Cardiospermum halicacabum Linn, Continuous Hot Percolation, Diuretic activity, Furosemide.

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