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Deshmukh, V.
- Anti-nociceptive Activity of Mundulea sericea Leaves
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Journal of Natural Remedies, Vol 4, No 2 (2004), Pagination: 127-130Abstract
Objective: To study the analgesic activity of leaves of Mundulea sericea. Methods: Methanolic extract (30 mg/kg and 70 mg/kg) of Mundulea sericea (Leguminosae, subfamily Papilionaceae) was investigated for analgesic activity using acetic acid-induced writhing and tail immersion method. The extract was studied for its effect on pentobarbitone-induced sleep and on gross behavior. Results: Methanolic extract (30 mg/kg and 70 mg/kg) significantly increased latency to flick tail in tail immersion test and reduced the number of writhings induced by acetic acid. The extract increased the duration of pentobarbitone-induced sleep. No adverse effects were observed upto a dose of 200 mg/kg of the extract. Conclusion: Leaves of Mundulea sericea possess central as well as peripheral analgesic activity.Keywords
Mundulea sericea, Analgesic, Tail Immersion, Writhing- Thyroid Disorders in Pregnancy: Illustrative Cases
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Authors
V. Deshmukh
1,
A. Joshi
2
Affiliations
1 Dinanath Mangeshkar Hospital, Pune, IN
2 Topiwala National Medical College and BYL Nair Hospital, Mumbai, IN
1 Dinanath Mangeshkar Hospital, Pune, IN
2 Topiwala National Medical College and BYL Nair Hospital, Mumbai, IN