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Sangavi, T.
- Green Remediation using the Monocot Grass Vetiveria zizanoides (L.) Nash
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Authors
Affiliations
1 PG and Research Department of Botany, Vellalar College for Women (Autonomous), Erode - 638012, Tamil Nadu, IN
1 PG and Research Department of Botany, Vellalar College for Women (Autonomous), Erode - 638012, Tamil Nadu, IN
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ScieXplore: International Journal of Research in Science, Vol 7, No 1-2 (2020), Pagination: 20-25Abstract
Now-a-days our environment is laden with contaminants. Heavy metals are important among them. These are toxic and may cause threat to living organisms and the environment. The conventional methods used for heavy metal removal have their limitations because they are ineffective, economically expensive and produce large quantities of sludge. So, there is a need to develop a cost efficient and eco-friendly method to alleviate this type of pollution. The current study was carried out to evaluate the phytoremediation capacity of Vetiveria zizanoides for heavy metals from polluted water. The objectives of the present research were to grow the test plant in nutrient solution with different concentrations (50, 100, 150 and 200 μM) of Lead acetate for 20 days. Fresh and dry biomass of vegetative parts (above and below ground) was determined and the Bio-concentration and Translocation factor was calculated. Results revealed that most of the lead from the solution was absorbed by Vetiveria zizanoides till the 20th day. The highest lead content was recorded in the root of the plant. Control plants did not record lead content in its tissues.Keywords
Lead and Environment, Phytoremediation, Vetiveria zizanoides.References
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- Development of Silymarin Entrapped Chitosan Phthalate Nanoparticles for Targeting Colon Cancer
Abstract Views :87 |
PDF Views:71
Authors
Affiliations
1 Department of Pharmaceutics, Crescent School of Pharmacy, B. S. Abdur Rahman Crescent Institute of Science and Technology, Chennai - 600048, IN
1 Department of Pharmaceutics, Crescent School of Pharmacy, B. S. Abdur Rahman Crescent Institute of Science and Technology, Chennai - 600048, IN
Source
Journal of Natural Remedies, Vol 22, No 4 (2022), Pagination: 659-671Abstract
The present paper deals with the development of silymarin entrapped Chitosan Phthalate (CP) nanoparticles for targeting colon cancer. The QbD approach is applied to optimize the silymarin loaded chitosan phthalate nanoparticles. DOE was employed to evaluate the dependent variables from the responses of CP nanoparticles. The CP NPs were found to be 140% of mucoadhesivity at pH 7.4, superior to pH 1.2 (10%). The result revealed the chemical or ionic bond formation between the positively charged amino groups of chitosan phthalate and the negatively charged sialic acid residue of mucin present in the mucous membrane. In vitro drug release profiles were carried out under acidic and basic pH conditions. The release of encapsulated silymarin was found to be poor in acidic conditions and maximum in basic conditions. The results suggested that chitosan phthalate nanoparticles could have the potential to enhance the bioavailability of silymarin.Keywords
Chitosan Phthalate, Colon Cancer, Design of Experiments (DOE), Nanoparticles, Quality by Design (QbD), Silymarin.References
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