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Paul, Swati

• Achieving Millennium Development Goals by 2015 in Bangladesh: Dream and Reality

Abstract Views :953  |  PDF Views:3

Authors

Muhammad Ridwan Mostafa ¹, Anwar Hossain Choudhury ¹, Swati Paul ², Dibyajyoti Saha ²

Affiliations
1 Department of Sociology, University of Chittagong, Chittagong, BD
2 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD

Source

Research Journal of Humanities and Social Sciences, Vol 4, No 1 (2013), Pagination: 1-11

Abstract

Bangladesh is the signatory country to implement Millennium Development Goals by 2015. Bangladesh has achieved remarkable success in eradicate poverty, primary education, gender equality and reduces child mortality. In all aspect of MDGs indicators, Bangladesh has revealed positive sign to meet the target. By reviewing literature related to MDGs, this paper is an attempt to see the progress of MDGs in Bangladesh in terms of all MDGs Goals, and its indicators. This paper highlights that, whereas Bangladesh is on track and need attention for achieving MDGs.

Keywords

Millennium Development Goals, Bangladesh, Progress, Status

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References

• BRAC.2012. Bangladesh-A Next-11 country in the twenty first century, BRAC Annual Report 2011.Dhaka.
• GED (2005). Bangladesh Unlocking the Potential, National Strategy for Accelerated Poverty Reduction, Dhaka: General Economics Division, Bangladesh Planning Commission, Government of Bangladesh.. p-15.
• Bangladesh. Retrieved August 19, 2012 from http://transition.usaid.gov/bd/bangladesh.html
• GED (2012). Millennium Development Goals, Bangladesh Progress Report 2011. Dhaka: General Economics Division, Bangladesh Planning Commission, Government of Bangladesh.p.7
• MDGs and Bangladesh: Retrieved August 20,2012 from http://www.undp.org.bd/mdgs.php
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• GED (2012). op.cit,p.19
• Titumir, Rashed Al Mahmud,. Rahman,K.M. Mustafizur,2011, Poverty and Inequality in Bangladesh, Unnayan Onneshan-The Innovators, Dhaka, Bangladesh, p.9.
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• GED (2012). op.cit,p.38
• The Daily Star.2012.Gender Equity Index on Bangladesh, the Daily Star, The Daily Star, Dhaka, Mach 08, 2012.
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• GED (2010). Outline Perspective Plan of Bangladesh 2010- 2021: Making vision 2021 a reality, Dhaka: General Economics Division, Bangladesh Planning Commission, Government of Bangladesh. P.20.
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• Bangladesh and development: The path through the fields, Retrieved 03/11/2012 from http://www.economist.com/news/briefing/21565617- bangladesh-has-dysfunctional-politics-and-stunted-privatesector- yet-it-has-been-surprisingly
• Maternal and Neonatal Health in Bangladesh, Retrieved October 08,2012 from http://www.unicef.org/bangladesh/Maternal_and_Neonatal_Hea lth.pdf
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• HIV /AIDS in Bangladesh. Retrieved October 21,2012, from http://en.wikipedia.org/wiki/HIV/AIDS_in_Bangladesh
• Selim,Dr Shajada..(April, 28, 2011). Malaria situation in Bangladesh, The Daily Sun, Dhaka, Bangladesh.
• The Daily Star.(2012).Bangladesh 5th most disaster prone country, The Daily Star, Dhaka, Saturday, October 13, 2012.
• GED (2010).op.cit, p.81.
• GED.(2012).op.cit,p.87
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• Bangladesh : Out of the basket, Retrieved November 3,2012 from http://www.economist.com/news/leaders/21565627- lessons-achievements%E2%80%94yes-reallyachievements% E2%80%94-bangladesh-out-basket

• In Vitro Antioxidant Activity of Methanolic Aerial Part Extract of Mimosa pudica

Abstract Views :309  |  PDF Views:2

Authors

Md. Omar Faruk ¹, Dibyajyoti Saha ², Srikanta Chowdhury ¹, Swati Paul ², Md. Golam Kabir ¹

Affiliations
1 Department of Biochemistry and Molecular Biology, University of Chittagong, Chittagong-4331, BD
2 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD

Source

Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 4 (2012), Pagination: 202-205

Abstract

The methanol crude extracts of the plant parts of Mimosa pudica (Mimosaceae) was screened was screened in vitro for antioxidant activity using the 1, 1-diphenyl-2-picrylhydrazyl-hydrate (DPPH) free radical scavenging assay. On the other hand, the methanol crude extract of the aerial part showed moderate antioxidant activity (IC50 20.512 μg/ml) compared to ascorbic acid (IC50 1.143 μg/ml). The overall experimental results suggest the biologically active constituents present in the methanolic extract of Mimosa pudica and justify its use in folkloric remedies.

Keywords

Mimosa pudica, Mimosaceae, DPPH, Antioxidant Activity.

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References

• Das S, Das S, Pal S, Mujib A, Dey S. (1999) Biotechnology of medicinal plants-Recent advances and potential. 1st Ed. Vol II. pp. 126-139. UK992 Publications, Hydarabad.
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• Ghani A. (2003) Medicinal Plants of Bangladesh, 2nd Ed. pp. 302-303. The Asiatic Society of Bangladesh, Dhaka.
• Genest S, Kerr C, Shah A, Rahman MM, Saif-E-Naser EMM, Nigam P, Nahar L, Sarker SD.(2008) Comparative bioactivity studies on two Mimosa species. Bol. Latinoam Caribe. Plant Med Aromaticus. 7(1): 38-43.
• Yuan K, Jia A, Lu JL, Zhu JX. (2007) Structural identification of new C glycosyl flavones from Mimosa pudica. Chin J An Chem. 35: 739-742.
• Balakrishnan N, Bhasker VH, Jayakar B, Sangameswaran B. (2006) Antibacterial activity of Mimosa pudia, Aegle marmelos and Sida cordifolia. Pharmacog Mag. 2(7): 198-199.
• Dinda B, Gosh B, Arima S, Sato N, Harigaya Y (2006) Steroids and terpinoids from Mimosa pudica ischolar_mains. J Indian Chem. Soc. 83: 1044-1046.
• Bum EN, Dawack DL, Schmutz M, Rakotonorina A, Rakotonorina VS, Portet C, Jeker A, Olpe HR, Herding P. (2004) Anticonvulsant activity of Mimosa pudica decoction.Fitoterapia. 75: 309-314.
• Kirk LF, Moller MV, Christensen J, Steak D, Ekpe P, Jaroszewski KW. (2003) A 5- deoxuflavonol derivatives in Mimosa pudica. Biochem Systamatics Ecol. 31: 103-105.
• Brand-Williams, W., Cuvelier, M.E. and Berset, C. 1995.Use of a free radical method to evaluate antioxidant activity, Lebensmittel-Wissenschaft und-Technologie/Food Science and Technology, 28:25-30.
• Koleva II, Van Beek TA, Linssen JPH, de Gischolar_main A, Evstatieva LN (2002) Screening of plant extracts for antioxidant activity: a comparative study on three testing methods. Phytochemical Analysis 13: 8-17
• Kanatt R. Chander et al, 2007 Antioxidant potential of mint (Mentha spicata L.) in radiation process lamb meat. Food chem. 100: 451-458.
• Aqil, F., I. Ahmad and Z. Mehmood, 2006. Antioxidant and free radical scavenging properties of twelve traditionally used Indian medicinal plants. Turk. J. Biol., 30: 177-183.
• Malencic, D., O. Gasic, M. Popovic and P. Boza, 2000. Screening for antioxidant properties of Salvia reflexa hornem. Phytother. Res., 14: 546-548.
• Stivala, L., M. Savio, O. Cazzalini, R. Pizzala and L. Rehak et al., 1996. Effect of -carotene on cell cycle progression of human fibroblasts. Carcinogenesis, 17: 2395-2401.
• Lee, J.J., Leedale, G.F. and Bradbury, P. 2000. An Illustrated Guide to the Protozoa, Second Edition. Society of Protozoologists, Lawrence, Kansas, U.S.A.
• Rice-Evans C, Sampson J, Bramley PM and Holloway DE (1997). Why do we expect carotenoids to be antioxidants in vivo? Free Radical Research 26: 381–398.

• Pharmacognostic Studies of Aerial Part of Methanolic Extract of Plumbago indica L

Abstract Views :313  |  PDF Views:4

Authors

Dibyajyoti Saha ¹, Swati Paul ²

Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD
2 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong

Source

Asian Journal of Research in Pharmaceutical Sciences, Vol 2, No 3 (2012), Pagination: 88-90

Abstract

The aerial part of Plumbago indica L. (family: Plumbaginaceae) was studied to fix the parameters for pharmacognostical standards. The results of organoleptic study offer a scientific basis for the use of Plumbago indica L. which possess characters like green colour, characteristic odour, mucilaginous and slightly bitter taste. The fluorescence analysis under visible UV light and under UV light by treatment with different chemical reagents showed different colour changes. These created an interest to test the possible phytochemical activity of the plant. In the screening process of Plumbago indica L. indicate the presence of Reducing sugars , Alkaloids, Steroids, Flavonoids and Gums. The Pharmacognostic study was performed by using standard procedure. Further, detailed studies are needed to know whether in-vivo administration of the extracts is beneficial for patients.

Keywords

Organoleptic, Fluorescence, Pharmacognostic Study.

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References

• Reddy, K.J. (2004): Medicinal plant research scenario in India, Info concepts India Inc., pp.25-28.
• Dubey, N.K., Kumar, R. and Tripathi, P. (2004): Global promotion of herbal medicine: India's opportunity, Current Science, 86(1), pp.37-41.
• Gaikwadi, S.S., Vadlamudi, V.P., Waghmaee, S.P., Maral, V.J., Ranteke, V.D. and Dhok, A.P. (2003): Phytochemical analysis of aqueous extract of few medicinal plants, PKV. Res. J., 27(1), pp.91-92.
• Van Der Vijver Lm. Distribution of plumbagin in the Plumbaginaceae. Phytochemistry 1974, Vol 11, Pages 3247- 3248.
• Bala Rathinasabapathi, Walid M. Fouad, and Celia A. Sigua . β- Alanine Betaine Synthesis in the Plumbaginaceae. Purification and Characterization of a Trifunctional, S-Adenosyl-l- Methionine-Dependent N-Methyltransferase from Limonium latifolium Leaves. Plant Physiol. 2001, Vol 126(3), Pages 1241- 1249.
• Jackson, B.P. and Snowdown, D.W. (1968): Powdered vegetable drugs, Cheer Chil Ltd., London, pp.25.
• Kokoshi, G.J., Kokoshi, J.R. and Sharma, F.J. (1958): Fluorescence of powdered vegetable drugs under ultra violet radiation, J. Amer. Pharm. Assn., 38(10), pp.715-717.
• Chase, C.R. and Pratt, R.F. (1949): Fluorescence of powdered vegetable drugs with particular reference to the development of systems of identification, J. American Pharm. Assoc., 38, pp.324- 333.
• Pandey, H.C., Dixit, R.S. and Sharma, H.P. (1984): Addition to the Pharmacognosy of Kalimulri (Curculigo orchioides), Bull. Med. Ethnobot. Res., 5(1-2), pp. 55-56.

• Evaluation of Antimotility Effect of Plumbago indica (L.) on Charcoal Induced Gastrointestinal Motility in Mice

Abstract Views :316  |  PDF Views:4

Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh Chittagong, BD

Source

Asian Journal of Research in Pharmaceutical Sciences, Vol 2, No 3 (2012), Pagination: 95-97

Abstract

Evaluation of antimotility activity was done in intestine of mice treated with methanolic extract of Plumbago indica L. (MEPI).Charcoal was used as a promotility agent. The antimotility activity with the mean defecation period 302.2 and 376.4min at the dose of 250 and 500mg/kg body weight.

Keywords

Plumbago indica L., Gastrointestinal Motility, Chacoal.

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References

• Massee B, McGahey C: A Framework for Action; Child Diarrhea Prevention. Global healthlink, a publication of the Global Health Council, www.globalhealth.org 2001., (111):
• Harrison TR: Diarrhea and Constipation. In Principles of internal medicine. 16th edition. New York: Macgraw Hill; 2005:224-232.
• Hardman JG, Limbird LE: Goodman's and Gilman's: Drugs affecting gastrointestinal function. In The pharmacological basis of therapeutics. 10th edition. New York: Macgraw Hill; 2001:1023-1024.
• Chitme HR, Chandra R, Kaushik S: Studies on anti-diarrhoeal activity of Calotropis gigantea R.Br. in experimental animals. J Pharm Pharmaceut Sci 2004, 7:70-75.
• Van Der Vijver Lm. Distribution of plumbagin in the Plumbaginaceae. Phytochemistry 1974, Vol 11, Pages 3247-3248.
• Bala Rathinasabapathi, Walid M. Fouad, and Celia A. Sigua . β-Alanine Betaine Synthesis in the Plumbaginaceae. Purification and Characterization of a Trifunctional, S-Adenosyl-l-Methionine-Dependent N-Methyltransferase from Limonium latifolium Leaves. Plant Physiol. 2001, Vol 126(3), Pages 1241-1249.
• Herida Regina Nunes Marona and Maria Beatriz Bastos LUCCHESI , (2004) , Protocol ofr Refine Intestinal Motility in mice and rats, 38: 257-260.

• Overview on Water Resources and Pollution

Abstract Views :257  |  PDF Views:1

Authors

Swati Paul ¹, Dibyajyoti Saha ², S. M. Zahid Hosen ², Talha Bin Emran ²

Affiliations
1 Department of Pharmacy, BGC Trust University, Bangladesh, Chittagong, BD
2 Department of Pharmacy, BGC Trust University, Bangladesh, Chittagong, BD

Source

Research Journal of Science and Technology, Vol 4, No 3 (2012), Pagination: 108-114

Abstract

Water resources are sources of water that are useful or potentially useful. Uses of water include agricultural, industrial, household, recreational and environmental activities. Water pollution is the contamination of water bodies (e.g. lakes, rivers, oceans, aquifers and groundwater). Water pollution occurs when pollutants are discharged directly or indirectly into water bodies without adequate treatment to remove harmful compounds. Water pollution affects plants and organisms living in these bodies of water. In almost all cases the effect is damaging not only to individual species and populations, but also to the natural biological communities.

Keywords

Water, Resources, Pollution, Hydrological.

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• Pharmacognostic Studies of Aerial Part of Methanolic Extract of Alpinia conchigera Griff

Abstract Views :246  |  PDF Views:0

Authors

Dibyajyoti Saha ¹, Swati Paul ¹

Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD

Source

Asian Journal of Pharmaceutical Analysis, Vol 2, No 2 (2012), Pagination: 46-48

Abstract

The aerial part of Alpinia conchigera Griff (family: Zingiberaceae,) was studied to fix the parameters for pharmacognostical standards. The results of organoleptic study offer a scientific basis for the use of Alpinia conchigera Griff which possess characters like green colour, characteristic odour, mucilaginous and slightly bitter taste. The fluorescence analysis under visible UV light and under UV light by treatment with different chemical reagents showed different colour changes. These created an interest to test the possible phytochemical activity of the plant. In the screening process of Alpinia conchigera Griff indicate the presence of Reducing sugars, Steroids, Alkaloids, Flavonoids, Saponins and Gums. The Pharmacognostic study was performed by using standard procedure. Further, detailed studies are needed to know whether in-vivo administration of the extracts is beneficial for patients.

Keywords

Organoleptic, Fluorescence, Pharmacognostic Study.

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• Comparative Studies on Sedimentation Parameter of Aluminium Hydroxide and Sodium Bicarbonate, Magnesium Trisilicate, Magnesium Carbonate Suspension

Abstract Views :216  |  PDF Views:0

Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD

Source

Asian Journal of Pharmacy and Technology, Vol 2, No 4 (2012), Pagination: 133-134

Abstract

The sedimentation volume (F) is defined as the ratio of final or ultimate volume to the suspension volume. If the volume of sedimentation in a flocculated suspension equal to the original volume of suspension, then F=1 is pharmaceutically acceptable. When F=0 it means the total drug has sedimented and volume of sediment is negligible. So, more the volume of F more will be therapeutic acceptance. In this study two types of suspension were studied where aluminium hydroxide suspension classed as type-I and sodium-bi-carbonate, magnesium trisilicate, magnesium carbonate suspension classed as ty pe-II suspension. It was observed that the sedimentation volume is more in case of type-I suspension rather than type-II suspension.

Keywords

Sedimentation Volume, Aluminium Hydroxide, Sodium Bi Carbonate, Magnesium Trisilicate, Magnesium Carbonate.

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• Pharmacognostic Studies of Aerial Part of Pouzolzia zeylanica (L.)

Abstract Views :231  |  PDF Views:0

Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD

Source

Asian Journal of Pharmacy and Technology, Vol 2, No 4 (2012), Pagination: 141-142

Abstract

The aerial part of Pouzolzia zeylanica (L.) Benn (fam. Urticaeae) was studied to fix the parameters for pharmacognostical standards. The results of organoleptic study offer a scientific basis for the use of Pouzolzia zeylanica which possess characters like greenish grey colour, characteristic odour and mucilaginous and slightly bitter taste. The fluorescence analysis under visible light and under UV light by treatment with different chemical reagents showed different colour changes. The presence of alkaloids, glycosides, tannins and flavonoids was confirmed during preliminary phytochemical screening.

Keywords

Organoleptic, Fluorescence, Phytochemical, Supernatant.

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• In Vitro Screening of Antifungal Activity of Methanol Extract of Alpinia Conchigera Griff against Some Pathogenic Species of Fungi

Abstract Views :262  |  PDF Views:0

Authors

Dibyajyoti Saha ¹, Swati Paul ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Pharmacy and Technology, Vol 2, No 2 (2012), Pagination: 44-46

Abstract

The main objective of the present study was to determine the methanolic extract of Alpinia conchigera Griff for antifungal activity. To determine the antifungal activitiy agar disc diffusion method was used. The antifungal activity of the extracts was compared with standard drug Fluconazole (500 μg/disc). The methanol extract of Alpinia conchigera Griff showed very good antifungal activity ranging from zone of inhibition (7.0-26) mm and Aspergillus niger was the most susceptible fungal strain of the methanolic extract of Alpinia conchigera Griff. Due to these promising results, further in vivo studies over Alpinia conchigera Griff must be conducted.

Keywords

Alpinia conchigera Griff, Methanol Extract, Antifungal Activity.

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• Cytotoxic Activity of Methanolic Extract of Plumbago Indica L. (Family: Plumbaginaceae)

Abstract Views :219  |  PDF Views:0

Authors

Dibyajyoti Saha ¹, Swati Paul ²

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD
2 Department of Pharmacy, BGC Trust University, Chittagong, IN

Source

Asian Journal of Pharmacy and Technology, Vol 2, No 2 (2012), Pagination: 59-61

Abstract

Investigation with crude methanolic extract of Plumbago indica L. was carried out to evaluate its possible cytotoxic activity. Pharmacological history of this plant promoted us to check the possible cytotoxic activity. By using the brine shrimp lethality bioassay method, the LC50 and LC90 value of Plumbago indica L. was assayed. In this study, DMSO was used as solvent. The extract evidence cytotoxic activity against brine shrimp nauplii and calculated LC₅₀ and LC₉₀ value was 5.0μg/ml and 12 μg/ml respectively.

Keywords

Plumbago indica L. , Cytotoxicity, LC₅₀, Brine Shrimp Lethality Bioassay, LC₉₀.

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• Analgesic Activity of Methanol Extract of Plumbago Indica (L.) by Acetic Acid Induced Writhing Method

Abstract Views :246  |  PDF Views:2

Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Pharmacy and Technology, Vol 2, No 2 (2012), Pagination: 74-76

Abstract

The present study was designed to investigate Analgesic activity of methanolic extract of Plumbago indica (L.) using Acetic Acid Induced Writhing method. Methanolic extract was administered intraperitoneally at doses of 250 mg/kg and 500 mg/kg to Young Swiss-albino mice. Methanol Extract of Plumbago indica (L.) showed significant inhibition in pain response induced by thermal and mechanical stimuli in dose dependent manner. The obtained results provide promising baseline information for the potential use of these crude extract in the treatment of pain.

Keywords

Plumbago indica (L.), Analgesic, Acetic Acid, Writhing Method.

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• Pharmacognostic Studies on Aerial Part of Methanolic Extract of Mimosa Pudica

Abstract Views :216  |  PDF Views:0

Authors

Swati Paul ¹, Dibyajyoti Saha ¹, Srikanta Chowdhury ²

Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD
2 Department of Biochemistry and Molecular Biology, University of Chittagong, BD

Source

Asian Journal of Pharmacy and Technology, Vol 2, No 3 (2012), Pagination: 101-103

Abstract

The aerial part of Mimosa pudica (family: (Mimosaceae)) was studied to fix the parameters for pharmacognostical standards. The results of organoleptic study offer a scientific basis for the use of Mimosa pudica which possess characters like deep green colour, characteristic odour and slightly bitter taste. The fluorescence analysis under visible UV light by treatment with different chemical reagents showed different colour changes. These created an interest to test the possible phytochemical activity of the plant. In the screening process of Mimosa pudica indicate the presence of alkaloids, glycoloids, flavonoids, terpenoids, steroids, phlobatanins, tannins and saponins .The pharmacognostic study was performed by using standard procedure. Further, detailed studies are needed to know whether in-vivo administration of the extracts is beneficial for patients.

Keywords

Organoleptic, Phytochemical, Fluorescence, Mimosa pudica.

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• Pharmacognostic Studies of Aerial Part of Methanolic Extract of Tridax procumbens

Abstract Views :212  |  PDF Views:0

Authors

Dibyajyoti Saha ¹, Swati Paul ¹

Affiliations
1 Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, BD

Source

Asian Journal of Pharmacy and Technology, Vol 2, No 3 (2012), Pagination: 107-109

Abstract

The aerial part of Tridax procumbens(family: Asteraceae) was studied to fix the parameters for pharmacognostical standards.The results of organoleptic study offer a scientific basis for the use of Tridax procumbens which possess characters like green colour, characteristic odour, mucilaginous and slightly bitter taste. The fluorescence analysis under visible UV light and under UV light by treatment with different chemical reagents showed different colour changes. These created an interest to test the possible phytochemical activity of the plant. In the screening process of Tridax procumbens indicate the presence of Reducing sugars, Steroids, Alkaloids, Glycosides, Tannins, Flavonoids and Gums. The Pharmacognostic study was performed by using standard procedure. Further, detailed studies are needed to know whether in-vivo administration of the extracts is beneficial for patients.

Keywords

Organoleptic, Fluorescence, Pharmacognostic Study.

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• Cytotoxic Activity of Ethanol Extract of Leea indica Leaf

Abstract Views :255  |  PDF Views:1

Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Research in Pharmaceutical Sciences, Vol 2, No 4 (2012), Pagination: 137-139

Abstract

The cytotoxic activity of ethanol extract of Leea indica (Burm. f.) Merr., (Family: Leeaceae) leaf has been investigated in the present study. The cytotoxic activity of the L. indica ethanol extract was assessed by brine shrimp lethality bioassay method. In brine shrimp lethality bioassay LC₅₀ value of L. indica ethanol extract was found 2.4771μg/ml with 95% confidence limit where the lower and upper limits were 2.2561 and 2.6981 μg/ml respectively, which indicates that the leaf extract has promising cytotoxic effect. The present study demonstrates that ethanol extract of L. indica leaf has significant cytotoxic effect.

Keywords

Leea indica, Cytotoxic, Brine Shrimp Lethality Bioassay, LC₅₀.

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• In Vitro Screening of Antifungal Activity of Methanol Extract of Plumbago indica L. against some Pathogenic Species of Fungi

Abstract Views :204  |  PDF Views:2

Authors

Dibyajyoti Saha ¹, Swati Paul ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Research in Pharmaceutical Sciences, Vol 2, No 2 (2012), Pagination: 55-57

Abstract

The main objective of the present study was to determine the methanolic extract of Plumbago indica L. for antifungal activity. To determine the antifungal activity, agar disc diffusion method was used. The antifungal activity of the extracts was compared with standard drug Fluconazole (500 μg/disc). The methanol extract of Plumbago indica L. showed very good antifungal activity ranging from zone of inhibition (10.0-27.0) mm and Candida albicans was the most susceptible fungal strain of the methanolic extract of. Plumbago indica L .Due to these promising results, further in vivo studies over Plumbago indica L. must be conducted.

Keywords

Plumbago indica L., Methanol Extract, Antifungal Activity.

Full Text

     

• Analgesic Activity of Methanol Extract of Alpinia conchigera Griff by Acetic Acid Induced Writhing Method

Abstract Views :243  |  PDF Views:2

Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Research in Pharmaceutical Sciences, Vol 2, No 2 (2012), Pagination: 62-65

Abstract

The present study was designed to investigate Analgesic activity of methanolic extract of Alpinia conchigera Griff, using Acetic Acid Induced Writhing method. Methanolic extract was administered intraperitoneally at doses of 250 mg/kg and 500 mg/kg to Young Swiss-albino mice. Methanol Extract of Alpinia conchigera Griff showed significant inhibition in pain response induced by thermal and mechanical stimuli in dose dependent manner. The obtained results provide promising baseline information for the potential use of these crude extract in the treatment of pain.

Keywords

Alpinia conchigera Griff, Analgesic, Acetic Acid, Writhing Method.

Full Text

     

• Pharmacognostic Studies on Methanolic Extract of the Aerial Part of Leucas zeylanica(L.)

Abstract Views :237  |  PDF Views:1

Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Pharmaceutical Research, Vol 2, No 4 (2012), Pagination: 142-143

Abstract

The aerial part of Leucas zeylanica (L.) Benn (Fam. Lamiaceae) was studied to fix the parameters for pharmacognostical standards. The results of organoleptic study offer a scientific basis for the use of Leucas zeylanica which possess characters like deep green colour, characteristic odor and mucilaginous and slightly bitter taste. The fluorescence analysis under visible light and under UV light by treatment with different chemical reagents showed different colour changes. The presence of alkaloids, steroids, tannins, flavonoids and glycosides were confirmed during preliminary phytochemical screening.

Keywords

Organoleptic, Fluorescence, Phytochemical, Supernatant.

Full Text

     

• Pharmacognostic Studies of Aerial Part of Methanolic Extract of Vernonia patula

Abstract Views :235  |  PDF Views:1

Authors

Dibyajyoti Saha ¹, Swati Paul ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Pharmaceutical Research, Vol 2, No 3 (2012), Pagination: 94-96

Abstract

The aerial part of Vernonia patula (family: Asteraceae) was studied to fix the parameters for pharmacognostical standards. The results of organoleptic study offer a scientific basis for the use of Vernonia patula which possess characters like green colour, characteristic odour, mucilaginous and slightly bitter taste. The fluorescence analysis under visible UV light and under UV light by treatment with different chemical reagents showed different colour changes. These created an interest to test the possible phytochemical activity of the plant. In the screening process of Vernonia patula indicate the presence of Reducing sugars, Steroids, Alkaloids, Glycosides, Tannins, and Gums. The Pharmacognostic study was performed by using standard procedure. Further, detailed studies are needed to know whether in-vivo administration of the extracts is beneficial for patients.

Keywords

Organoleptic, Fluorescence, Pharmacognostic Study.

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• Comparative Study of the Efficacy of Barleria prionitis Leaf Extracts against Bacteria

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Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Pharmaceutical Research, Vol 2, No 3 (2012), Pagination: 107-110

Abstract

Bacterial infections are one of the prominent causes of health problems, physical disabilities and mortalities around the world. Symptoms and complications associated with bacterial infections such as fever, chills, headache, nausea, vomiting and organ failures affect patient's life severely. Medicinal plants are a rich source of antimicrobial agents and provide a safer and cost effective way of treating bacterial infections. We report in this work for the first time, the potent antibacterial activity of different leaf extracts of Barleria prionotis L. The objectives of this study were to examine the antibacterial effect using different extract [petroleum ether (40°-60°), chloroform, ethanol (70%)] and column fraction of Barleria prionitis Linn (Acanthaceae) leaf and to determine the minimum inhibitory concentration (MIC) of the different Barleria prionitis Linn (Acanthaceae) leaf extract and column fraction. S. typhi (Ty 2-59) [Chloroform extract, Column fraction]; V. cholerae (DN-6) [Column fraction]; V. cholerae (793) [Chloroform extract]; V. cholerae (813) [Chloroform extract, Column fraction]; M. luteus (ATCC-9341) [Chloroform extract, Column fraction]; L. sporogenus [Chloroform extract] and Citrobacter [Chloroform extract, Column fraction] were inhibited at 5mg/ml level. B. subtils (PI-6633) [Pet. ether extract] inhibited at 3.33mg/ml level. B. cereus (PI-11778) [Column fraction] and Providencia [Chloroform extract, Column fraction] were inhibited at 50mg/ml level.

Keywords

Barleria prionitis, Antibacterial Activity, Minimum Inhibitory Concentration (MIC).

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• Evaluation of Antimotility Effect of Alpinia conchigera Griff on Charcoal Induced Gastrointestinal Motility in Mice

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Authors

Swati Paul ¹, Dibyajyoti Saha ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Pharmaceutical Research, Vol 2, No 2 (2012), Pagination: 71-74

Abstract

Evaluation of antimotility activity was done in intestine of mice treated with methanolic extract of Alpinia conchigera Griff (MEAC). Charcoal was used as a promotility agent. The antimotility activity with the mean defecation period 297.4 and 371.2 min at the dose of 250 and 500mg/kg body weight.

Keywords

Alpinia conchigera Griff, Gastrointestinal Motility, Chacoal.

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• Cytotoxic Activity of Methanolic Extract of Alpinia conchigera Griff (Family:Zingiberaceae)

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Authors

Dibyajyoti Saha ¹, Swati Paul ¹

Affiliations
1 Department of Pharmacy, BGC Trust University, Chittagong, BD

Source

Asian Journal of Pharmaceutical Research, Vol 2, No 2 (2012), Pagination: 86-88

Abstract

Investigation with crude methanolic extract of Alpinia conchigera Griff was carried out to evaluate its possible cytotoxic activity. Pharmacological history of this plant promoted us to check the possible cytotoxic activity. By using the brine shrimp lethality bioassay method, the LC50 and LC90 value of Alpinia conchigera Griff were assayed. In this study, DMSO was used as solvent. The extract evidence cytotoxic activity against brine shrimp nauplii and calculated LC₅₀ and LC₉₀ value was 6.1μg/ml and 12.2 μg/ml respectively.

Keywords

Alpinia conchigera Griff, Cytotoxicity, LC₅₀, Brine Shrimp Lethality Bioassay, LC₉₀.

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