Informatics Publishing Limited

Virendra C. Patil ¹, Chetan Galande ¹, Neeraj Desai ¹, Shilpa Patil ¹, Sumit Agrawal ¹

Affiliations
1 Dept. of Medicine, KIMSU Karad, Maharashtra State, IN

Abstract

Background: Alcohol consumption has serious economic, social and medical consequences. Chronic alcohol consumption can lead to serious medical consequences especially neurologic disorder. So far there is scanty of literature about neurological manifestations of alcohol consumption in India and overseas.

Aims&Objectives: To study the various neurological manifestations, clinical profile and prognostic factors of patients admitted with history of alcohol consumption. Material&Method: This was a retrospective, observational study, which included 312 alcoholic patients admitted in the medicine department, during one year period (January 2012 to December 2012). Data was analysed by SPSS statistical package trial version 11.

Results: A total 312 (3.28%) were admitted with significant history of alcohol consumption. All patients were males with age >15 yrs. Out of 312 patients 146 (46.8%) had neurological manifestations at the time of presentation. Out of 146 patients 13 (8.92%) had ischemic stroke, 2 (1.36%) had intracranial hemorrhage and 3 (2.08%) had cortical venous sinus thrombosis. and 10 (6.84 %) with seizures. A total 7 (4.81 %) presented with hypoglycemia, 5 (3.42 %) presented with meningitis, and 2 (1.36%) presented with neuropathy. A total 36 (24.65 %) had alcohol withdrawal syndrome and 38 (26.02 %) patients were admitted with alcohol intoxication and 30 (20.54 %) presented with Wernicke-Korsakoff syndrome. Total 25 (8.01 %) patients succumbed with alcohol consumption. Out of 25 deaths 12 (48 %) deaths were associated with neurological manifestations and 13 (52 %) with non neurological complications. Total deaths were 25 (8.01%) with mean age of 50.96 ± 8.7 yrs. Mortality was associated with increasing age hypoglycemia and seizures in neurological complications ('p'<0.0231).

Conclusions: Half of patients with alcohol consumption had neurological manifestations and associated morbidity and mortality. Alcohol withdrawal syndrome, W-K syndrome and alcohol intoxication were common neurological manifestation. Mortality was more associated with neurological manifestations compared to the non-neurological complication.

Keywords

Wernicke-korsakoff Syndrome, Neurological Manifestations, Alcohol Withdrawal Syndrome, Hypoglycemia, Seizures

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Virendra C. Patil ¹, Chetan Galande ¹, Neeraj Desai ¹, Sumit Agrawal ¹

Affiliations
1 Department of Medicine Krishna Institute of Medical, Sciences University (KIMSU), Dhebewadi Road, Karad Dist: Satara, Maharashtra, IN

Abstract

This is case report of 30 year male, presented with fever and thrombocytopenia, diagnosed as Dengue fever. Worsened neurologically three days after admission and developed subarachnoid hemorrhage. Patient was treated with platelet concentrate transfusion. Patient underwent decompression hemicraniotomy for increased intracranial pressure. Patient had some improvement at the end of 20 days. Although neurological complications reported for dengue fever are unusual, it is reasonable to consider these manifestations for immediate management and better outcome of patient.

Keywords

Dengue Fever, Subarachnoid Hemorrhage, Thrombocytopenia, Neurological Complications

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Yogendra Kumar Jain ¹, Abhishek Kesharwani ¹, Sumit Agrawal ¹, Tirath Prasad Sahu ¹

Affiliations
1 Department of CSE, Samrat Ashok Technological Institute, Vidisha (M.P.), IN

Abstract

Image enhancement is basic problem in the field of image processing & it can be subdivided into many categories like edge enhancement, smoothing, contrast enhancement, bright enhancement, sharpness enhancement etc. The classical approach treats the operations using linear systems which creates many computational problems and also does not match to human visual perception and interpretation logic. In this work we propose a LIP (Logarithmic Image Processing) technique in combination with MDBUTMF (Modified Decision Based Unsymmetric Trimmed Median Filter) for contrast and sharpness enhancement with capability to suppress the noise. LIP uses non-linear operations for image manipulation which are computationally effective. In LIP, image processing specific arithmetic operations are introduced which ensure that there is no loss of information in the form of ―out-of-range‖ pixel values. MDBUTMF is a very efficient median filter and it is capable of de-noising images which are corrupted with high density salt and pepper noise. Thus the combination of these techniques results in an efficient image enhancement algorithm. MDBUTMF is first applied to de-noise the input image. The de-noised image is further processed by LIP based enhancement methods to generate the final output. All the implementation work has been done in MATLAB 10.0 image processing tool box. Simulation results show a marked improvement in performance in terms of removal of noise, contrast, sharpness, detail enhancement, and Overall quality of image as compared to existing algorithms.

Keywords

Image Enhancement, Sharpness Enhancement, Noise Reduction, LIP (Logarithmic Image Processing), Median Filter.

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