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- Somnath Patel
- Ritesh Patel
- Shraddha
- Pushpendra
- Sachin
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- Kuldeep
- Prashant
- Rajesh Patel
- Girish
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- Tomanlal
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- Mukta Agrawal
- Ajazuddin
- D. K. Tripathi
- Amit Alexander
- Umesh Kumar Sahu
- Jyotsana Meshram
- Ranjeeta Kumari
- Harish Sharma
- Gyanesh Kumar Sahu
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Tripathi, Shubham
- A Review on Biocompatible Hydrogel: Formulation Aspect and Evaluation
Abstract Views :514 |
PDF Views:0
Authors
Shubham Tripathi
1,
Somnath Patel
1,
Ritesh Patel
1,
Shraddha
1,
Pushpendra
1,
Sachin
1,
Neetish
1,
Mahendra
1,
Kuldeep
1,
Prashant
1,
Rajesh Patel
1,
Girish
1,
Nitin
1,
Tomanlal
1,
Amrita Thakur
1,
Mukta Agrawal
1,
Ajazuddin
1,
D. K. Tripathi
1,
Amit Alexander
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai - 490024, Chhattisgarh, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 119-122Abstract
Many predefined ways are now a day adopted to interface with biological tissues. One such significant class of biomaterials are hydrogels, which are defined as highly hydrated materials. Hydrogels are designed to absorb a large amount of water or biological fluids due to its three-dimensional, hydrophilic, polymeric network. They closely simulate natural living tissue, more so than any other class of synthetic biomaterials because of their high-water content, porosity,and soft consistency.They are chemically stable but may degrade and gradually disintegrate up to dissolve. Now a day they become more popular because of their unique property of flexibility and biocompatibility. Hydrogels can be produced by both natural and synthetic polymers. These polymers undergo physical and chemical cross-linking to produce hydrogels. Due to their resemblance to the living tissue, they have the immense possibility to use hydrogels in the biomedical field. Some of the well-known use of hydrogels include manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery system and wound dressings. The current review article deals with information about the hydrogels, their various types, preparation methods along with an evaluation of the same.Also, the present study is performed for the motivation of the graduates towards publication and research. Hence, we have encouraged the graduates to prepare an informative article on the present subject.Keywords
Hydrogel, Polymeric Network, Porosity, Biocompatibility, Biomedical.References
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- Dwivedi S, Khatri P, Mehra GR,Kumar V. Hydrogel-A Conceptual Overview. International Journal of Pharmaceutical and Biological Archives. 2011; 2(6): 1588-1597.
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- Formulation and Characterization of Virgin Coconut Oil Emulsion (VCOE) for Treatment of Alzheimer’s Disease
Abstract Views :537 |
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Authors
Shubham Tripathi
1,
Umesh Kumar Sahu
1,
Jyotsana Meshram
1,
Ranjeeta Kumari
1,
D. K. Tripathi
1,
Ajazuddin
1,
Amit Alexander
1,
Harish Sharma
2,
Gyanesh Kumar Sahu
1
Affiliations
1 Rungta College of Pharmaceutical Sciences and Research, Kohka Kurud Road, Bhilai, IN
2 Shri Shankaracharya technical campus, Shri Shankaracharya group of institution, Faculty of Pharmacy, Junwani, Bhilai, IN
1 Rungta College of Pharmaceutical Sciences and Research, Kohka Kurud Road, Bhilai, IN
2 Shri Shankaracharya technical campus, Shri Shankaracharya group of institution, Faculty of Pharmacy, Junwani, Bhilai, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 10, No 2 (2018), Pagination: 49-54Abstract
Alzheimer’s disease, is a somatic disease that affects the brain. It is a progressive disease that destroys memory and other important mental functions. During this disease, accumulation of cerebral extracellular amyloid, which is mostly composed of accumulated amyloid-β (Ab) peptide as well as the accumulation of intracellular neurofibrillary tangles, appears to start up. This results in the loss of connection between nerve cell, and lead to the degeneration of neurons and finally death of brain tissue. Also due to the deficiency of some important chemical messenger in the brain, the signal transmission gets ultimately, affected in the body. The main objective of this study was to prepare the optimized formula of a VCO based emulsion containing Tween 20 as the surfactant for treatment of Alzheimer’s disease which may help to increase the cholesterol level in the brain and to destroy the β amyloid plaque as a result of which the level of chemical messenger will increase in the brain. This study is further aimed to analyze, concentration of drug reaching into the brain and to study its effect in destroying β amyloid plaque.Keywords
Amyloid-β, Chemical Messengers, Neurofibrillary, Tangles, Peptide, Cholesterol.References
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- VaibhavKumar Dapurkar, Harish Sharma, Gyanesh Kumar Sahu, Swati Meshram, Dr. GopalRai, Anti arthritic activity of ischolar_mains extract of boerhaaviadiffusa in adjuvant induced arthritis rats, Scholar academic journal of pharmacy 2013 2(2): 107-109.
- GyaneshKumar Sahu, Harish Sharma, Anshita Gupta, Chanchal Deep Kaur, A review article on advancement in microemulsion based drug delivery system for better therapeutic effect, International journal of pharmaceutical sciences and developmental research , Aug 2015.
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- GyaneshKumar Sahu, Harish Sharma, ChanchalDeep Kaur, A novel approach of magnetic modulated microspheres, Asian J. of research, 2013, vol III, Issue 4, page 220-224.
- Gyaneshkumarsahu, Harish sharma, Dr. GopalRai, Vaibhav Kumar Dapurkar, Development and evaluation of methotreaxate loaded BSA microsphere, International research journal of pharmaceutical and applied science, 2012; 2(5); 9-12.
- Bony R. Shah, DhruboJyotiSen, Rajesh Bahekar. Design, Synthesis and Pharmacological Evaluation of Potent and Selective Dipeptidyl-Derived Inhibitors as New Class of Antidiabetic Drugs. Asian J. Research Chem. 4(1): January 2011; Page 50-54.
- SunitaSoni, Ajay Soni, Sunil Ganatra. Studies on the Optimum Reaction Time for Commercial Cholesterol kits. Asian J. Research Chem. 6(10): October 2013; Page 950-951.
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- Characterization of Different Forms of Chalcopyrite Disease through Fractal Analysis
Abstract Views :218 |
PDF Views:78
Authors
Affiliations
1 Department of Geology, University of Delhi, Delhi 110 007, IN
2 Department of Physics, SGTB Khalsa College, University of Delhi, Delhi 110 007, IN
1 Department of Geology, University of Delhi, Delhi 110 007, IN
2 Department of Physics, SGTB Khalsa College, University of Delhi, Delhi 110 007, IN
Source
Current Science, Vol 117, No 3 (2019), Pagination: 460-469Abstract
Complex shapes that form by natural processes are often difficult to explain using non-Euclidean geometry. Chalcopyrite disease (CD) formation, a replacement texture, demonstrates a nonlinear-fractal geometry. CD samples from three polymetallic deposits were chosen for fractal analysis. CD did not show a fractal value specific to mineralized deposits. However, fractal analysis showed consistent values for a similar form of CD, thus setting a quantitative relationship between varied forms of CD and their condition of formation. The mean fractal dimension calculated for each study area displayed a positive correlation with the peak metamorphic grade of the respective deposit. The statistical analysis (ANOVA) of fractal dimension data further delineated the differences among the three study areas.Keywords
Box Counting Method, Chalcopyrite Disease, Fractal Dimension, Replacement Texture, Statistical Analysis.References
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- Evolution and Dynamics of the Denitrification in the Arabian Sea on Millennial to Million-Year Timescale
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Authors
Affiliations
1 National Centre for Polar and Ocean Research, Ministry of Earth Sciences, Vasco-da-Gama, Goa 403 804, IN
1 National Centre for Polar and Ocean Research, Ministry of Earth Sciences, Vasco-da-Gama, Goa 403 804, IN